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Abnormal peripheral action potential amplitude

MedGen UID:
868204
Concept ID:
C4022596
Finding
HPO: HP:0030179

Definition

An anomaly in the magnitude of the action potential along a peripheral nerve, that is, of the rapid rise and fall of the electrical membrane potential of the nerve. [from HPO]

Professional guidelines

PubMed

Doneddu PE, Gentile L, Cocito D, Fazio R, Luigetti M, Briani C, Filosto M, Siciliano G, Benedetti L, Antonini G, Matà S, Marfia GA, Inghilleri M, Manganelli F, Cosentino G, Brighina F, Carpo M, Carta F, Mazzeo A, Peci E, Strano C, Romano A, Campagnolo M, Cotti-Piccinelli S, Viola DV, Germano F, Leonardi L, Sperti M, Mataluni G, Ceccanti M, Spina E, Vegezzi E, Di Stefano V, Nobile-Orazio E
Eur J Neurol 2024 May;31(5):e16248. Epub 2024 Feb 20 doi: 10.1111/ene.16248. PMID: 38376074
Ginanneschi F, Mignarri A, Mondelli M, Gallus GN, Del Puppo M, Giorgi S, Federico A, Rossi A, Dotti MT
J Neurol 2013 Jan;260(1):268-74. Epub 2012 Aug 10 doi: 10.1007/s00415-012-6630-3. PMID: 22878431
Oh SJ, Hatanaka Y, Ohira M, Kurokawa K, Claussen GC
Muscle Nerve 2012 Feb;45(2):195-9. doi: 10.1002/mus.22287. PMID: 22246874

Recent clinical studies

Etiology

Stępień J, Pastuszak Ż
J Neurophysiol 2023 Feb 1;129(2):392-398. Epub 2022 Dec 14 doi: 10.1152/jn.00396.2022. PMID: 36515426Free PMC Article
Li Y, Zhang X, Zhao C
Neurol Res 2021 Oct;43(10):793-801. Epub 2021 Jun 8 doi: 10.1080/01616412.2021.1935101. PMID: 34101535
Tsuji Y, Ueda T, Sekiguchi K, Nishiyama M, Kanda F, Nishigori C, Toda T, Matsumoto R
Muscle Nerve 2020 Oct;62(4):534-540. Epub 2020 Aug 10 doi: 10.1002/mus.27028. PMID: 32696477
Ashrafi MR, Mohammadalipoor A, Naeini AR, Amanat M, Tavasoli AR, Heidari M, Badv RS, Mohammadi M, Zamani GR, Rahimi-Dehgolan S, Rahimi R, Akbari MG
J Child Neurol 2020 Jun;35(7):448-455. Epub 2020 Mar 10 doi: 10.1177/0883073820905157. PMID: 32156188
Pérez-Riera AR, Abreu LC, Yanowitz F, Barros RB, Femenía F, McIntyre WF, Baranchuk A
Cardiol J 2012;19(4):337-46. doi: 10.5603/cj.2012.0063. PMID: 22825893

Diagnosis

Doneddu PE, Gentile L, Cocito D, Fazio R, Luigetti M, Briani C, Filosto M, Siciliano G, Benedetti L, Antonini G, Matà S, Marfia GA, Inghilleri M, Manganelli F, Cosentino G, Brighina F, Carpo M, Carta F, Mazzeo A, Peci E, Strano C, Romano A, Campagnolo M, Cotti-Piccinelli S, Viola DV, Germano F, Leonardi L, Sperti M, Mataluni G, Ceccanti M, Spina E, Vegezzi E, Di Stefano V, Nobile-Orazio E
Eur J Neurol 2024 May;31(5):e16248. Epub 2024 Feb 20 doi: 10.1111/ene.16248. PMID: 38376074
Li Y, Zhang X, Zhao C
Neurol Res 2021 Oct;43(10):793-801. Epub 2021 Jun 8 doi: 10.1080/01616412.2021.1935101. PMID: 34101535
Fisher MA
ScientificWorldJournal 2007 Feb 2;7:144-60. doi: 10.1100/tsw.2007.49. PMID: 17334607Free PMC Article
Eisen A
Neurol Clin 1985 Aug;3(3):495-510. PMID: 2995782
Buchthal F, Behse F
Electroencephalogr Clin Neurophysiol Suppl 1978;(34):373-83. PMID: 220006

Therapy

Dalla Torre C, Zambello R, Cacciavillani M, Campagnolo M, Berno T, Salvalaggio A, De March E, Barilà G, Lico A, Lucchetta M, Ermani M, Briani C
Neurology 2016 Sep 13;87(11):1161-6. Epub 2016 Aug 17 doi: 10.1212/WNL.0000000000003093. PMID: 27534712
Sahenk Z, Galloway G, Clark KR, Malik V, Rodino-Klapac LR, Kaspar BK, Chen L, Braganza C, Montgomery C, Mendell JR
Mol Ther 2014 Mar;22(3):511-521. Epub 2013 Oct 28 doi: 10.1038/mt.2013.250. PMID: 24162799Free PMC Article
Gawel M, Jamrozik Z, Szmidt-Salkowska E, Slawek J, Gawel D, Rowińska-Marcińska K, Kaminska A
J Neurol Sci 2013 Jan 15;324(1-2):136-9. Epub 2012 Nov 10 doi: 10.1016/j.jns.2012.10.023. PMID: 23146616
Park SB, Lin CS, Kiernan MC
J Vis Exp 2012 Apr 26;(62) doi: 10.3791/3439. PMID: 22565594Free PMC Article
Sundkvist G, Armstrong FM, Bradbury JE, Chaplin C, Ellis SH, Owens DR, Rosén I, Sönksen P
J Diabetes Complications 1992 Apr-Jun;6(2):123-30. doi: 10.1016/1056-8727(92)90023-e. PMID: 1611136

Prognosis

Papantoniou M, Rentzos M, Zampelis T, Tzavellas E, Paparrigopoulos T, Kokotis P
Alcohol 2024 Jun;117:65-71. Epub 2024 Apr 3 doi: 10.1016/j.alcohol.2024.04.001. PMID: 38580031
Dhanapalaratnam R, Issar T, Poynten AM, Milner KL, Kwai NCG, Krishnan AV
Eur J Neurol 2022 Dec;29(12):3571-3579. Epub 2022 Sep 14 doi: 10.1111/ene.15534. PMID: 36039540Free PMC Article
Lei L, Chen H, Lu Y, Zhu W, Ouyang Y, Duo J, Chen Z, Da Y
J Neurol 2021 Mar;268(3):1050-1058. Epub 2020 Sep 30 doi: 10.1007/s00415-020-10246-2. PMID: 32997296
Karam C, Klein CJ, Dispenzieri A, Dyck PJ, Mandrekar J, D'Souza A, Mauermann ML
Neurology 2015 May 12;84(19):1981-7. Epub 2015 Apr 15 doi: 10.1212/WNL.0000000000001565. PMID: 25878176Free PMC Article
Pérez-Riera AR, Abreu LC, Yanowitz F, Barros RB, Femenía F, McIntyre WF, Baranchuk A
Cardiol J 2012;19(4):337-46. doi: 10.5603/cj.2012.0063. PMID: 22825893

Clinical prediction guides

Stępień J, Pastuszak Ż
J Neurophysiol 2023 Feb 1;129(2):392-398. Epub 2022 Dec 14 doi: 10.1152/jn.00396.2022. PMID: 36515426Free PMC Article
Tsuji Y, Ueda T, Sekiguchi K, Nishiyama M, Kanda F, Nishigori C, Toda T, Matsumoto R
Muscle Nerve 2020 Oct;62(4):534-540. Epub 2020 Aug 10 doi: 10.1002/mus.27028. PMID: 32696477
Ashrafi MR, Mohammadalipoor A, Naeini AR, Amanat M, Tavasoli AR, Heidari M, Badv RS, Mohammadi M, Zamani GR, Rahimi-Dehgolan S, Rahimi R, Akbari MG
J Child Neurol 2020 Jun;35(7):448-455. Epub 2020 Mar 10 doi: 10.1177/0883073820905157. PMID: 32156188
Ohashi N, Kodaira M, Morita H, Sekijima Y
Amyloid 2019 Mar;26(1):15-23. Epub 2019 Jan 26 doi: 10.1080/13506129.2018.1564903. PMID: 30688105
Pérez-Riera AR, Abreu LC, Yanowitz F, Barros RB, Femenía F, McIntyre WF, Baranchuk A
Cardiol J 2012;19(4):337-46. doi: 10.5603/cj.2012.0063. PMID: 22825893

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