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Facial muscle hypertrophy

MedGen UID:
868297
•Concept ID:
C4022691
•
Finding
Synonyms: Hyperplasia of facial muscles; Increased size of facial muscles; Large facial muscles
 
HPO: HP:0012892

Definition

Hypertrophy of one or more muscles innervated by the facial nerve (the seventh cranial nerve). [from HPO]

Term Hierarchy

CClinical test,  RResearch test,  OOMIM,  GGeneReviews,  VClinVar  
  • CROGVFacial muscle hypertrophy

Professional guidelines

PubMed

International Consensus Recommendations on the Aesthetic Usage of Ready-to-Use AbobotulinumtoxinA (Alluzience).
Ascher B, Rzany BJ, Kestemont P, Redaelli A, Hendrickx B, Iozzo I, Martschin C, Milotich A, Molina B, Cartier H, Picaut P, Prygova I
Aesthet Surg J 2024 Jan 16;44(2):192-202. doi: 10.1093/asj/sjad222. PMID: 37490767Free PMC Article
Phenotype Genotype Characterization of FKRP-related Muscular Dystrophy among Indian Patients.
Unnikrishnan G, Polavarapu K, Bardhan M, Nashi S, Vengalil S, Preethish-Kumar V, Valasani RK, Huddar A, Nishadham V, Nandeesh BN, Nalini A
J Neuromuscul Dis 2023;10(4):615-626. doi: 10.3233/JND-221618. PMID: 37154180Free PMC Article
Lower facial remodeling with botulinum toxin type A for the treatment of masseter hypertrophy.
Klein FH, Brenner FM, Sato MS, Robert FM, Helmer KA
An Bras Dermatol 2014 Nov-Dec;89(6):878-84. doi: 10.1590/abd1806-4841.20143200. PMID: 25387491Free PMC Article

Recent clinical studies

Etiology

Are lower urinary tract conditions more common in children with sleep bruxism?
Ceyhan E, Hasirci E, Gezgin O, Senirkentli GB, Aygun YC
J Pediatr Urol 2023 Apr;19(2):176.e1-176.e6. Epub 2022 Dec 1 doi: 10.1016/j.jpurol.2022.11.024. PMID: 36522240
Alternative Clinical Indications of Botulinum Toxin.
Alster TS, Harrison IS
Am J Clin Dermatol 2020 Dec;21(6):855-880. doi: 10.1007/s40257-020-00532-0. PMID: 32651806
The Masseter Muscle and Its Role in Facial Contouring, Aging, and Quality of Life: A Literature Review.
Almukhtar RM, Fabi SG
Plast Reconstr Surg 2019 Jan;143(1):39e-48e. doi: 10.1097/PRS.0000000000005083. PMID: 30303926
Association between signs and symptoms of bruxism and presence of tori: a systematic review.
Bertazzo-Silveira E, Stuginski-Barbosa J, Porporatti AL, Dick B, Flores-Mir C, Manfredini D, De Luca Canto G
Clin Oral Investig 2017 Dec;21(9):2789-2799. Epub 2017 Feb 17 doi: 10.1007/s00784-017-2081-7. PMID: 28213765
Botulinum toxin for masseter hypertrophy.
Fedorowicz Z, van Zuuren EJ, Schoones J
Cochrane Database Syst Rev 2013 Sep 9;2013(9):CD007510. doi: 10.1002/14651858.CD007510.pub3. PMID: 24018587Free PMC Article

Diagnosis

Deep Neck Lift: Defining Anatomical Problems and Choosing Appropriate Treatment Strategies.
Marten T, Elyassnia D
Facial Plast Surg 2022 Dec;38(6):630-649. Epub 2022 Dec 23 doi: 10.1055/s-0042-1757729. PMID: 36563673
Botulinum Toxin Injections for Masseter Reduction in East Asians.
Cheng J, Hsu SH, McGee JS
Dermatol Surg 2019 Apr;45(4):566-572. doi: 10.1097/DSS.0000000000001859. PMID: 30883483
Association between signs and symptoms of bruxism and presence of tori: a systematic review.
Bertazzo-Silveira E, Stuginski-Barbosa J, Porporatti AL, Dick B, Flores-Mir C, Manfredini D, De Luca Canto G
Clin Oral Investig 2017 Dec;21(9):2789-2799. Epub 2017 Feb 17 doi: 10.1007/s00784-017-2081-7. PMID: 28213765
Evaluation of the upper airway in obstructive sleep apnoea.
Togeiro SM, Chaves CM Jr, Palombini L, Tufik S, Hora F, Nery LE
Indian J Med Res 2010 Feb;131:230-5. PMID: 20308748
Mandibular angloplasty.
Kim HC, Kameyama T
Kurume Med J 1992;39(3):147-51. doi: 10.2739/kurumemedj.39.147. PMID: 1491548

Therapy

Botulinum Toxin for Treating Temporomandibular Disorders: What is the Evidence?
Delcanho R, Val M, Guarda Nardini L, Manfredini D
J Oral Facial Pain Headache 2022 Winter;36(1):6-20. doi: 10.11607/ofph.3023. PMID: 35298571Free PMC Article
The Masseter Muscle and Its Role in Facial Contouring, Aging, and Quality of Life: A Literature Review.
Almukhtar RM, Fabi SG
Plast Reconstr Surg 2019 Jan;143(1):39e-48e. doi: 10.1097/PRS.0000000000005083. PMID: 30303926
Overview of Botulinum Toxins for Aesthetic Uses.
Gart MS, Gutowski KA
Clin Plast Surg 2016 Jul;43(3):459-71. Epub 2016 May 4 doi: 10.1016/j.cps.2016.03.003. PMID: 27363760
Bilateral hypertrophy of masseteric and temporalis muscles, our fifteen patients and review of literature.
Graziano P, Dell'Aversana Orabona G, Astarita F, Ponzo LM, Nunziata R, Salzano G, Maglitto F, Solari D, Santella A, Cappabianca M, Iaconetta G, Califano L
Eur Rev Med Pharmacol Sci 2016;20(1):7-11. PMID: 26813447
Botulinum toxin for masseter hypertrophy.
Fedorowicz Z, van Zuuren EJ, Schoones J
Cochrane Database Syst Rev 2013 Sep 9;2013(9):CD007510. doi: 10.1002/14651858.CD007510.pub3. PMID: 24018587Free PMC Article

Prognosis

Assessment of Electromyographic Changes in a Patient with Masseter Hypertrophy and Muscle Pain after Botulinum Injections: A Case Report and 5 Months Follow-up.
Bianco E, Tagliabue R, Mirabelli L, Maddalone M
J Contemp Dent Pract 2022 Feb 1;23(2):226-231. PMID: 35748454
Temporal volume increase after reduction of masseteric hypertrophy utilizing incobotulinumtoxin type A.
Nikolis A, Enright KM, Rudolph C, Cotofana S
J Cosmet Dermatol 2020 Jun;19(6):1294-1300. Epub 2020 Apr 27 doi: 10.1111/jocd.13434. PMID: 32338450Free PMC Article
Somatic GNAQ mutation in different structures of port-wine macrocheilia.
Ma G, Yu Z, Liu F, Wang L, Yu W, Zhu J, Gu H, Liu Y, Cai R, Lin X
Br J Dermatol 2018 Nov;179(5):1109-1114. Epub 2018 Aug 14 doi: 10.1111/bjd.16830. PMID: 29878304
Muscular and functional changes following adenotonsillectomy in children.
Bueno Dde A, Grechi TH, Trawitzki LV, Anselmo-Lima WT, Felício CM, Valera FC
Int J Pediatr Otorhinolaryngol 2015 Apr;79(4):537-40. Epub 2015 Jan 28 doi: 10.1016/j.ijporl.2015.01.024. PMID: 25669724
Temporalis muscle hypertrophy and reduced skull eccentricity in Duchenne muscular dystrophy.
Straathof CS, Doorenweerd N, Wokke BH, Dumas EM, van den Bergen JC, van Buchem MA, Hendriksen JG, Verschuuren JJ, Kan HE
J Child Neurol 2014 Oct;29(10):1344-8. Epub 2014 Mar 19 doi: 10.1177/0883073813518106. PMID: 24646504

Clinical prediction guides

Orbicularis Oculi Muscle Immunohistochemical, Metabolic, and Morphometric Differences in Affected and Nonaffected Sides in Hemifacial Spasm vs Healthy Subjects.
Osaki TH, Gameiro GR, Osaki MH, Osaki T, Campos ED, Belfort R Jr, Marie SKN
J Neuroophthalmol 2023 Sep 1;43(3):410-416. Epub 2022 Nov 25 doi: 10.1097/WNO.0000000000001770. PMID: 36730142
Are lower urinary tract conditions more common in children with sleep bruxism?
Ceyhan E, Hasirci E, Gezgin O, Senirkentli GB, Aygun YC
J Pediatr Urol 2023 Apr;19(2):176.e1-176.e6. Epub 2022 Dec 1 doi: 10.1016/j.jpurol.2022.11.024. PMID: 36522240
Gravitational forces, negative pressure and facial structure in the genesis of airway dysfunction during sleep: a review of the paradigm.
Stupak HD, Park SY
Sleep Med 2018 Nov;51:125-132. Epub 2018 Jul 6 doi: 10.1016/j.sleep.2018.06.016. PMID: 30165336
Association between signs and symptoms of bruxism and presence of tori: a systematic review.
Bertazzo-Silveira E, Stuginski-Barbosa J, Porporatti AL, Dick B, Flores-Mir C, Manfredini D, De Luca Canto G
Clin Oral Investig 2017 Dec;21(9):2789-2799. Epub 2017 Feb 17 doi: 10.1007/s00784-017-2081-7. PMID: 28213765
Mandibular angle resection and masticatory muscle hypertrophy - a technical note and morphological optimization.
Andreishchev AR, Nicot R, Ferri J
Rev Stomatol Chir Maxillofac Chir Orale 2014 Nov;115(5):301-7. Epub 2014 Jul 4 doi: 10.1016/j.revsto.2014.06.002. PMID: 25001550

Recent systematic reviews

Association between signs and symptoms of bruxism and presence of tori: a systematic review.
Bertazzo-Silveira E, Stuginski-Barbosa J, Porporatti AL, Dick B, Flores-Mir C, Manfredini D, De Luca Canto G
Clin Oral Investig 2017 Dec;21(9):2789-2799. Epub 2017 Feb 17 doi: 10.1007/s00784-017-2081-7. PMID: 28213765
Botulinum toxin for masseter hypertrophy.
Fedorowicz Z, van Zuuren EJ, Schoones J
Cochrane Database Syst Rev 2013 Sep 9;2013(9):CD007510. doi: 10.1002/14651858.CD007510.pub3. PMID: 24018587Free PMC Article
Botulinum toxin for masseter hypertrophy.
Al-Muharraqi MA, Fedorowicz Z, Al Bareeq J, Al Bareeq R, Nasser M
Cochrane Database Syst Rev 2009 Jan 21;(1):CD007510. doi: 10.1002/14651858.CD007510.pub2. PMID: 19160335

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