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Focal T2 hypointense thalamic lesion

MedGen UID:
868381
Concept ID:
C4022775
Finding
HPO: HP:0012691

Definition

A darker than expected T2 signal on magnetic resonance imaging (MRI) of the thalamus. This term refers to a localized hypointensity affecting a particular region of the thalamus. [from HPO]

Term Hierarchy

CClinical test,  RResearch test,  OOMIM,  GGeneReviews,  VClinVar  
  • CROGVFocal T2 hypointense thalamic lesion

Recent clinical studies

Etiology

Parry A, Clare S, Jenkinson M, Smith S, Palace J, Matthews PM
J Neurol 2002 Sep;249(9):1279-86. doi: 10.1007/s00415-002-0837-7. PMID: 12242554
Chan S, Kartha K, Yoon SS, Desmond DW, Hilal SK
AJNR Am J Neuroradiol 1996 Nov-Dec;17(10):1821-7. PMID: 8933864Free PMC Article
Kuenzle C, Baenziger O, Martin E, Thun-Hohenstein L, Steinlin M, Good M, Fanconi S, Boltshauser E, Largo RH
Neuropediatrics 1994 Aug;25(4):191-200. doi: 10.1055/s-2008-1073021. PMID: 7824091
Chamberlain MC, Press GA, Hesselink JR
AJNR Am J Neuroradiol 1989 May-Jun;10(3):491-6. PMID: 2501980Free PMC Article

Diagnosis

Soni N, Agarwal A, Ajmera P, Mehta P, Gupta V, Vibhute M, Gubbiotti M, Mark IT, Messina SA, Mohan S, Bathla G
AJNR Am J Neuroradiol 2024 Apr 8;45(4):468-474. doi: 10.3174/ajnr.A8166. PMID: 38485198
Yuen CA, Mastrianni J, Ali S, Pytel P, Park DM, Rezania K
Medicine (Baltimore) 2020 Sep 18;99(38):e22062. doi: 10.1097/MD.0000000000022062. PMID: 32957327Free PMC Article
Wendel C, Kaech DL, Woodtli M
J Neurol Surg A Cent Eur Neurosurg 2018 Jul;79(4):344-352. Epub 2018 Apr 12 doi: 10.1055/s-0038-1639504. PMID: 29649851
Pantano P, Caramia F, Pierallini A
Ital J Neurol Sci 1999;20(5 Suppl):S250-3. doi: 10.1007/s100729970006. PMID: 10662960
Kuenzle C, Baenziger O, Martin E, Thun-Hohenstein L, Steinlin M, Good M, Fanconi S, Boltshauser E, Largo RH
Neuropediatrics 1994 Aug;25(4):191-200. doi: 10.1055/s-2008-1073021. PMID: 7824091

Therapy

Yuen CA, Mastrianni J, Ali S, Pytel P, Park DM, Rezania K
Medicine (Baltimore) 2020 Sep 18;99(38):e22062. doi: 10.1097/MD.0000000000022062. PMID: 32957327Free PMC Article

Prognosis

Soni N, Agarwal A, Ajmera P, Mehta P, Gupta V, Vibhute M, Gubbiotti M, Mark IT, Messina SA, Mohan S, Bathla G
AJNR Am J Neuroradiol 2024 Apr 8;45(4):468-474. doi: 10.3174/ajnr.A8166. PMID: 38485198
Wendel C, Kaech DL, Woodtli M
J Neurol Surg A Cent Eur Neurosurg 2018 Jul;79(4):344-352. Epub 2018 Apr 12 doi: 10.1055/s-0038-1639504. PMID: 29649851
Kuenzle C, Baenziger O, Martin E, Thun-Hohenstein L, Steinlin M, Good M, Fanconi S, Boltshauser E, Largo RH
Neuropediatrics 1994 Aug;25(4):191-200. doi: 10.1055/s-2008-1073021. PMID: 7824091

Clinical prediction guides

Parry A, Clare S, Jenkinson M, Smith S, Palace J, Matthews PM
J Neurol 2002 Sep;249(9):1279-86. doi: 10.1007/s00415-002-0837-7. PMID: 12242554
Kuenzle C, Baenziger O, Martin E, Thun-Hohenstein L, Steinlin M, Good M, Fanconi S, Boltshauser E, Largo RH
Neuropediatrics 1994 Aug;25(4):191-200. doi: 10.1055/s-2008-1073021. PMID: 7824091

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