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EEG with temporal focal spikes

MedGen UID:
868670
•Concept ID:
C4023073
•
Finding
HPO: HP:0012018

Definition

EEG with focal sharp transient waves of a duration less than 80 msec in the temporal region. [from HPO]

Term Hierarchy

CClinical test,  RResearch test,  OOMIM,  GGeneReviews,  VClinVar  
  • EEG with temporal focal spikes

Conditions with this feature

Intellectual disability, autosomal dominant 42
MedGen UID:
934741
•Concept ID:
C4310774
•
Mental or Behavioral Dysfunction
GNB1 encephalopathy (GNB1-E) is characterized by moderate-to-severe developmental delay / intellectual disability, structural brain abnormalities, and often infantile hypotonia and seizures. Other less common findings include dystonia, reduced vision, behavior issues, growth delay, gastrointestinal (GI) problems, genitourinary (GU) abnormalities in males, and cutaneous mastocytosis.
See: Condition Record
Intellectual disability, autosomal dominant 42

Professional guidelines

PubMed

On the clinical utility of on-scalp MEG: A modeling study of epileptic activity source estimation.
Westin K, Beniczky S, Pfeiffer C, Hämäläinen M, Lundqvist D
Clin Neurophysiol 2023 Dec;156:143-155. Epub 2023 Oct 31 doi: 10.1016/j.clinph.2023.10.006. PMID: 37951041
Epileptic encephalopathy with electrical status epilepticus during slow sleep: evaluation of treatment response from a tertiary center.
Kılıç B, Acar M, Topçu Y, Turanlı G
Turk J Pediatr 2022;64(2):302-311. doi: 10.24953/turkjped.2020.2558. PMID: 35611419
Is there a place for surgical treatment of nonpharmacoresistant epilepsy?
Steinhoff BJ, Staack AM
Epilepsy Behav 2019 Feb;91:4-8. Epub 2018 Jun 28 doi: 10.1016/j.yebeh.2018.05.025. PMID: 29960857

Recent clinical studies

Etiology

Surgery for epilepsy.
West S, Nevitt SJ, Cotton J, Gandhi S, Weston J, Sudan A, Ramirez R, Newton R
Cochrane Database Syst Rev 2019 Jun 25;6(6):CD010541. doi: 10.1002/14651858.CD010541.pub3. PMID: 31237346Free PMC Article
Is there a place for surgical treatment of nonpharmacoresistant epilepsy?
Steinhoff BJ, Staack AM
Epilepsy Behav 2019 Feb;91:4-8. Epub 2018 Jun 28 doi: 10.1016/j.yebeh.2018.05.025. PMID: 29960857
Surgery for epilepsy.
West S, Nolan SJ, Cotton J, Gandhi S, Weston J, Sudan A, Ramirez R, Newton R
Cochrane Database Syst Rev 2015 Jul 1;(7):CD010541. doi: 10.1002/14651858.CD010541.pub2. PMID: 26130264
Idiopathic focal epilepsies.
Vigevano F, Specchio N, Fejerman N
Handb Clin Neurol 2013;111:591-604. doi: 10.1016/B978-0-444-52891-9.00061-0. PMID: 23622206
Unusual EEG patterns.
Westmoreland BF, Klass DW
J Clin Neurophysiol 1990 Apr;7(2):209-28. doi: 10.1097/00004691-199004000-00005. PMID: 2187021

Diagnosis

Surgery for epilepsy.
West S, Nevitt SJ, Cotton J, Gandhi S, Weston J, Sudan A, Ramirez R, Newton R
Cochrane Database Syst Rev 2019 Jun 25;6(6):CD010541. doi: 10.1002/14651858.CD010541.pub3. PMID: 31237346Free PMC Article
Is there a place for surgical treatment of nonpharmacoresistant epilepsy?
Steinhoff BJ, Staack AM
Epilepsy Behav 2019 Feb;91:4-8. Epub 2018 Jun 28 doi: 10.1016/j.yebeh.2018.05.025. PMID: 29960857
Surgery for epilepsy.
West S, Nolan SJ, Cotton J, Gandhi S, Weston J, Sudan A, Ramirez R, Newton R
Cochrane Database Syst Rev 2015 Jul 1;(7):CD010541. doi: 10.1002/14651858.CD010541.pub2. PMID: 26130264
Idiopathic focal epilepsies.
Vigevano F, Specchio N, Fejerman N
Handb Clin Neurol 2013;111:591-604. doi: 10.1016/B978-0-444-52891-9.00061-0. PMID: 23622206
Magnetoencephalography in epilepsy.
Knowlton RC, Shih J
Epilepsia 2004;45 Suppl 4:61-71. doi: 10.1111/j.0013-9580.2004.04012.x. PMID: 15281961

Therapy

Neurosteroids and Focal Epileptic Disorders.
Lévesque M, Biagini G, Avoli M
Int J Mol Sci 2020 Dec 10;21(24) doi: 10.3390/ijms21249391. PMID: 33321734Free PMC Article
Surgery for epilepsy.
West S, Nevitt SJ, Cotton J, Gandhi S, Weston J, Sudan A, Ramirez R, Newton R
Cochrane Database Syst Rev 2019 Jun 25;6(6):CD010541. doi: 10.1002/14651858.CD010541.pub3. PMID: 31237346Free PMC Article
Is there a place for surgical treatment of nonpharmacoresistant epilepsy?
Steinhoff BJ, Staack AM
Epilepsy Behav 2019 Feb;91:4-8. Epub 2018 Jun 28 doi: 10.1016/j.yebeh.2018.05.025. PMID: 29960857
Surgery for epilepsy.
West S, Nolan SJ, Cotton J, Gandhi S, Weston J, Sudan A, Ramirez R, Newton R
Cochrane Database Syst Rev 2015 Jul 1;(7):CD010541. doi: 10.1002/14651858.CD010541.pub2. PMID: 26130264
Occipital lobe seizures and epilepsies.
Adcock JE, Panayiotopoulos CP
J Clin Neurophysiol 2012 Oct;29(5):397-407. doi: 10.1097/WNP.0b013e31826c98fe. PMID: 23027097

Prognosis

Surgery for epilepsy.
West S, Nevitt SJ, Cotton J, Gandhi S, Weston J, Sudan A, Ramirez R, Newton R
Cochrane Database Syst Rev 2019 Jun 25;6(6):CD010541. doi: 10.1002/14651858.CD010541.pub3. PMID: 31237346Free PMC Article
Is there a place for surgical treatment of nonpharmacoresistant epilepsy?
Steinhoff BJ, Staack AM
Epilepsy Behav 2019 Feb;91:4-8. Epub 2018 Jun 28 doi: 10.1016/j.yebeh.2018.05.025. PMID: 29960857
Surgery for epilepsy.
West S, Nolan SJ, Cotton J, Gandhi S, Weston J, Sudan A, Ramirez R, Newton R
Cochrane Database Syst Rev 2015 Jul 1;(7):CD010541. doi: 10.1002/14651858.CD010541.pub2. PMID: 26130264
Idiopathic focal epilepsies.
Vigevano F, Specchio N, Fejerman N
Handb Clin Neurol 2013;111:591-604. doi: 10.1016/B978-0-444-52891-9.00061-0. PMID: 23622206
Occipital lobe seizures and epilepsies.
Adcock JE, Panayiotopoulos CP
J Clin Neurophysiol 2012 Oct;29(5):397-407. doi: 10.1097/WNP.0b013e31826c98fe. PMID: 23027097

Clinical prediction guides

Surgery for epilepsy.
West S, Nevitt SJ, Cotton J, Gandhi S, Weston J, Sudan A, Ramirez R, Newton R
Cochrane Database Syst Rev 2019 Jun 25;6(6):CD010541. doi: 10.1002/14651858.CD010541.pub3. PMID: 31237346Free PMC Article
Surgery for epilepsy.
West S, Nolan SJ, Cotton J, Gandhi S, Weston J, Sudan A, Ramirez R, Newton R
Cochrane Database Syst Rev 2015 Jul 1;(7):CD010541. doi: 10.1002/14651858.CD010541.pub2. PMID: 26130264
How to establish causality in epilepsy surgery.
Asano E, Brown EC, Juhász C
Brain Dev 2013 Sep;35(8):706-20. Epub 2013 May 15 doi: 10.1016/j.braindev.2013.04.004. PMID: 23684007Free PMC Article
Occipital lobe seizures and epilepsies.
Adcock JE, Panayiotopoulos CP
J Clin Neurophysiol 2012 Oct;29(5):397-407. doi: 10.1097/WNP.0b013e31826c98fe. PMID: 23027097
Current trends in electroencephalography.
Blume WT
Curr Opin Neurol 2001 Apr;14(2):193-7. doi: 10.1097/00019052-200104000-00010. PMID: 11262735

Recent systematic reviews

Spatio-temporal dynamics of interictal activity in musicogenic epilepsy: Two case reports and a systematic review of the literature.
Nuara A, Mirandola L, Fabbri-Destro M, Giovannini G, Vecchiato G, Vaudano AE, Tassinari CA, Avanzini P, Meletti S
Clin Neurophysiol 2020 Oct;131(10):2393-2401. Epub 2020 Jul 18 doi: 10.1016/j.clinph.2020.06.028. PMID: 32828042
Surgery for epilepsy.
West S, Nevitt SJ, Cotton J, Gandhi S, Weston J, Sudan A, Ramirez R, Newton R
Cochrane Database Syst Rev 2019 Jun 25;6(6):CD010541. doi: 10.1002/14651858.CD010541.pub3. PMID: 31237346Free PMC Article
Surgery for epilepsy.
West S, Nolan SJ, Cotton J, Gandhi S, Weston J, Sudan A, Ramirez R, Newton R
Cochrane Database Syst Rev 2015 Jul 1;(7):CD010541. doi: 10.1002/14651858.CD010541.pub2. PMID: 26130264
Comparison of antiepileptic drugs, no treatment, or placebo for children with benign epilepsy with centro temporal spikes.
Tan HJ, Singh J, Gupta R, de Goede C
Cochrane Database Syst Rev 2014 Sep 5;2014(9):CD006779. doi: 10.1002/14651858.CD006779.pub2. PMID: 25190506Free PMC Article

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