U.S. flag

An official website of the United States government

Format

Send to:

Choose Destination

Single ventricle of indeterminate morphology

MedGen UID:
868823
Concept ID:
C4023233
Congenital Abnormality
HPO: HP:0011680

Term Hierarchy

CClinical test,  RResearch test,  OOMIM,  GGeneReviews,  VClinVar  
  • CROGVSingle ventricle of indeterminate morphology

Conditions with this feature

Congenital heart defects, multiple types, 9
MedGen UID:
1841003
Concept ID:
C5830367
Congenital Abnormality
Multiple types of congenital heart defects-9 (CHTD9) is characterized by common arterial trunk (truncus arteriosus communis) in most patients, associated with other cardiac defects, including tetralogy of Fallot, interrupted aortic arch, right aortic arch, ventricular hypoplasia, and hypoplastic left heart, as well as other vascular and valvular anomalies (Ta-Shma et al., 2013; Guimier et al., 2023). For a general phenotypic description and discussion of genetic heterogeneity of multiple types of congenital heart defects, see CHTD1 (see 306955).

Professional guidelines

PubMed

Böckenhoff P, Hellmund A, Gottschalk I, Berg C, Herberg U, Geipel A, Gembruch U
Ultraschall Med 2023 Oct;44(5):e226-e240. Epub 2022 Jul 1 doi: 10.1055/a-1866-4538. PMID: 35777369Free PMC Article

Recent clinical studies

Etiology

Lillitos PJ, Nolan O, Cave DGW, Lomax C, Barwick S, Bentham JR, Seale AN
Arch Dis Child Fetal Neonatal Ed 2024 Jun 19;109(4):384-390. doi: 10.1136/archdischild-2023-326213. PMID: 38123956
Böckenhoff P, Hellmund A, Gottschalk I, Berg C, Herberg U, Geipel A, Gembruch U
Ultraschall Med 2023 Oct;44(5):e226-e240. Epub 2022 Jul 1 doi: 10.1055/a-1866-4538. PMID: 35777369Free PMC Article
Chaosuwannakit N, Makarawate P
J Cardiothorac Surg 2018 May 16;13(1):39. doi: 10.1186/s13019-018-0729-2. PMID: 29769130Free PMC Article
Kamata M, Stiver C, Naguib A, Tumin D, Tobias JD
J Cardiothorac Vasc Anesth 2017 Feb;31(1):128-133. Epub 2016 Jul 19 doi: 10.1053/j.jvca.2016.07.024. PMID: 27720490
Margossian RE, Solowiejczyk D, Bourlon F, Apfel H, Gersony WM, Hordof AJ, Quaegebeur J
J Thorac Cardiovasc Surg 2002 Sep;124(3):442-7. doi: 10.1067/mtc.2002.122299. PMID: 12202859

Diagnosis

Lee FT, Sun L, Szabo A, Milligan N, Saini A, Chetan D, Hunt JL, Macgowan CK, Freud L, Jaeggi E, Van Mieghem T, Kingdom J, Miller SP, Seed M
Ultrasound Obstet Gynecol 2024 Oct;64(4):493-503. doi: 10.1002/uog.27657. PMID: 38629477
Lillitos PJ, Nolan O, Cave DGW, Lomax C, Barwick S, Bentham JR, Seale AN
Arch Dis Child Fetal Neonatal Ed 2024 Jun 19;109(4):384-390. doi: 10.1136/archdischild-2023-326213. PMID: 38123956
Böckenhoff P, Hellmund A, Gottschalk I, Berg C, Herberg U, Geipel A, Gembruch U
Ultraschall Med 2023 Oct;44(5):e226-e240. Epub 2022 Jul 1 doi: 10.1055/a-1866-4538. PMID: 35777369Free PMC Article
Margossian RE, Solowiejczyk D, Bourlon F, Apfel H, Gersony WM, Hordof AJ, Quaegebeur J
J Thorac Cardiovasc Surg 2002 Sep;124(3):442-7. doi: 10.1067/mtc.2002.122299. PMID: 12202859
Shiraishi H, Silverman NH
J Am Coll Cardiol 1990 May;15(6):1401-8. doi: 10.1016/s0735-1097(10)80031-2. PMID: 2329242

Therapy

Lee FT, Sun L, Szabo A, Milligan N, Saini A, Chetan D, Hunt JL, Macgowan CK, Freud L, Jaeggi E, Van Mieghem T, Kingdom J, Miller SP, Seed M
Ultrasound Obstet Gynecol 2024 Oct;64(4):493-503. doi: 10.1002/uog.27657. PMID: 38629477
Kamata M, Stiver C, Naguib A, Tumin D, Tobias JD
J Cardiothorac Vasc Anesth 2017 Feb;31(1):128-133. Epub 2016 Jul 19 doi: 10.1053/j.jvca.2016.07.024. PMID: 27720490

Prognosis

Böckenhoff P, Hellmund A, Gottschalk I, Berg C, Herberg U, Geipel A, Gembruch U
Ultraschall Med 2023 Oct;44(5):e226-e240. Epub 2022 Jul 1 doi: 10.1055/a-1866-4538. PMID: 35777369Free PMC Article
Cieplucha A, Trojnarska O, Bartczak A, Kramer L, Grajek S
BMC Cardiovasc Disord 2013 Apr 3;13:26. doi: 10.1186/1471-2261-13-26. PMID: 23552339Free PMC Article
Truong UT, Li X, Broberg CS, Houle H, Schaal M, Ashraf M, Kilner P, Sheehan FH, Sable CA, Ge S, Sahn DJ
Am J Cardiol 2010 May 15;105(10):1465-9. Epub 2010 Mar 30 doi: 10.1016/j.amjcard.2009.12.074. PMID: 20451696
Margossian RE, Solowiejczyk D, Bourlon F, Apfel H, Gersony WM, Hordof AJ, Quaegebeur J
J Thorac Cardiovasc Surg 2002 Sep;124(3):442-7. doi: 10.1067/mtc.2002.122299. PMID: 12202859
Julsrud PR, Weigel TJ, Edwards WD
Pediatr Cardiol 1997 May-Jun;18(3):208-12. doi: 10.1007/s002469900152. PMID: 9142711

Clinical prediction guides

Lee FT, Sun L, Szabo A, Milligan N, Saini A, Chetan D, Hunt JL, Macgowan CK, Freud L, Jaeggi E, Van Mieghem T, Kingdom J, Miller SP, Seed M
Ultrasound Obstet Gynecol 2024 Oct;64(4):493-503. doi: 10.1002/uog.27657. PMID: 38629477
Cieplucha A, Trojnarska O, Bartczak A, Kramer L, Grajek S
BMC Cardiovasc Disord 2013 Apr 3;13:26. doi: 10.1186/1471-2261-13-26. PMID: 23552339Free PMC Article
Julsrud PR, Weigel TJ, Edwards WD
Pediatr Cardiol 1997 May-Jun;18(3):208-12. doi: 10.1007/s002469900152. PMID: 9142711
Sahn DJ, Harder JR, Freedom RM, Duncan WJ, Rowe RD, Allen HD, Valdes-Cruz L, Goldberg SJ
Circulation 1982 Nov;66(5):1070-7. doi: 10.1161/01.cir.66.5.1070. PMID: 7127691
Anderson RH, Tynan M, Freedom RM, Quero-Jiménez M, Macartney FJ, Shinebourne EA, Wilkinson JL, Becker AE
Herz 1979 Apr;4(2):184-97. PMID: 447181

Supplemental Content

Table of contents

    Clinical resources

    Practice guidelines

    • PubMed
      See practice and clinical guidelines in PubMed. The search results may include broader topics and may not capture all published guidelines. See the FAQ for details.

    Consumer resources

    Recent activity

    Your browsing activity is empty.

    Activity recording is turned off.

    Turn recording back on

    See more...