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Focal EEG discharges with secondary generalization

MedGen UID:
869068
•Concept ID:
C4023486
•
Finding
Synonym: Focal EEG discharges with secondary generalisation
 
HPO: HP:0011188

Definition

Focal EEG discharges that secondarily spread to both hemispheres and can then be recorded over the entire scalp. [from HPO]

Term Hierarchy

CClinical test,  RResearch test,  OOMIM,  GGeneReviews,  VClinVar  
  • CROGVFocal EEG discharges with secondary generalization

Professional guidelines

PubMed

Treatment and outcome in patients with febrile convulsion associated with epileptiform discharges on electroencephalography.
Okumura A, Ishiguro Y, Sofue A, Suzuki Y, Maruyama K, Kubota T, Negoro T, Watanabe K
Brain Dev 2004 Jun;26(4):241-4. doi: 10.1016/S0387-7604(03)00161-X. PMID: 15130690
Predictors in the treatment of difficult-to-control seizures by electrical stimulation of the centromedian thalamic nucleus.
Velasco F, Velasco M, Jiménez F, Velasco AL, Brito F, Rise M, Carrillo-Ruiz JD
Neurosurgery 2000 Aug;47(2):295-304; discussion 304-5. doi: 10.1097/00006123-200008000-00007. PMID: 10942002

Recent clinical studies

Etiology

Epileptogenicity in tuberous sclerosis complex: A stereoelectroencephalographic study.
Neal A, Ostrowsky-Coste K, Jung J, Lagarde S, Maillard L, Kahane P, Touraine R, Catenoix H, Montavont A, Isnard J, Arzimanoglou A, Bartolomei F, Guenot M, Rheims S
Epilepsia 2020 Jan;61(1):81-95. Epub 2019 Dec 20 doi: 10.1111/epi.16410. PMID: 31860139
Surgery for epilepsy.
West S, Nevitt SJ, Cotton J, Gandhi S, Weston J, Sudan A, Ramirez R, Newton R
Cochrane Database Syst Rev 2019 Jun 25;6(6):CD010541. doi: 10.1002/14651858.CD010541.pub3. PMID: 31237346Free PMC Article
Lateralized periodic discharges frequency correlates with glucose metabolism.
Subramaniam T, Jain A, Hall LT, Cole AJ, Westover MB, Rosenthal ES, Struck AF
Neurology 2019 Feb 12;92(7):e670-e674. Epub 2019 Jan 11 doi: 10.1212/WNL.0000000000006903. PMID: 30635488Free PMC Article
Spike-related haemodynamic responses overlap with high frequency oscillations in patients with focal epilepsy.
González Otárula KA, Khoo HM, von Ellenrieder N, Hall JA, Dubeau F, Gotman J
Brain 2018 Mar 1;141(3):731-743. doi: 10.1093/brain/awx383. PMID: 29360943Free PMC Article
Surgery for epilepsy.
West S, Nolan SJ, Cotton J, Gandhi S, Weston J, Sudan A, Ramirez R, Newton R
Cochrane Database Syst Rev 2015 Jul 1;(7):CD010541. doi: 10.1002/14651858.CD010541.pub2. PMID: 26130264

Diagnosis

The spectrum of sepsis-associated encephalopathy: a clinical perspective.
Sonneville R, Benghanem S, Jeantin L, de Montmollin E, Doman M, Gaudemer A, Thy M, Timsit JF
Crit Care 2023 Oct 5;27(1):386. doi: 10.1186/s13054-023-04655-8. PMID: 37798769Free PMC Article
Recognition of interictal and ictal discharges on EEG. Focal vs generalized epilepsy.
Andrade-Machado R, Benjumea Cuartas V, Muhammad IK
Epilepsy Behav 2021 Apr;117:107830. Epub 2021 Feb 25 doi: 10.1016/j.yebeh.2021.107830. PMID: 33639439
Surgery for epilepsy.
West S, Nevitt SJ, Cotton J, Gandhi S, Weston J, Sudan A, Ramirez R, Newton R
Cochrane Database Syst Rev 2019 Jun 25;6(6):CD010541. doi: 10.1002/14651858.CD010541.pub3. PMID: 31237346Free PMC Article
Surgery for epilepsy.
West S, Nolan SJ, Cotton J, Gandhi S, Weston J, Sudan A, Ramirez R, Newton R
Cochrane Database Syst Rev 2015 Jul 1;(7):CD010541. doi: 10.1002/14651858.CD010541.pub2. PMID: 26130264
Neurophysiology of spasms.
Vigevano F, Fusco L, Pachatz C
Brain Dev 2001 Nov;23(7):467-72. doi: 10.1016/s0387-7604(01)00284-4. PMID: 11701240

Therapy

Sex-related differences in adult patients with status epilepticus: a seven-year two-center observation.
Baumann SM, De Stefano P, Kliem PSC, Grzonka P, Gebhard CE, Sarbu OE, De Marchis GM, Hunziker S, Rüegg S, Kleinschmidt A, Pugin J, Quintard H, Marsch S, Seeck M, Sutter R
Crit Care 2023 Aug 5;27(1):308. doi: 10.1186/s13054-023-04592-6. PMID: 37543625Free PMC Article
Surgery for epilepsy.
West S, Nevitt SJ, Cotton J, Gandhi S, Weston J, Sudan A, Ramirez R, Newton R
Cochrane Database Syst Rev 2019 Jun 25;6(6):CD010541. doi: 10.1002/14651858.CD010541.pub3. PMID: 31237346Free PMC Article
Audiogenic kindling and secondary subcortico-cortical epileptogenesis: Behavioral correlates and electrographic features.
Vinogradova LV
Epilepsy Behav 2017 Jun;71(Pt B):142-153. Epub 2015 Jul 3 doi: 10.1016/j.yebeh.2015.06.014. PMID: 26148984
Surgery for epilepsy.
West S, Nolan SJ, Cotton J, Gandhi S, Weston J, Sudan A, Ramirez R, Newton R
Cochrane Database Syst Rev 2015 Jul 1;(7):CD010541. doi: 10.1002/14651858.CD010541.pub2. PMID: 26130264
Landau-Kleffner syndrome is not an eponymic badge of ignorance.
Hirsch E, Valenti MP, Rudolf G, Seegmuller C, de Saint Martin A, Maquet P, Wioland N, Metz-Lutz MN, Marescaux C, Arzimanoglou A
Epilepsy Res 2006 Aug;70 Suppl 1:S239-47. Epub 2006 Jun 27 doi: 10.1016/j.eplepsyres.2006.02.010. PMID: 16806832

Prognosis

The spectrum of sepsis-associated encephalopathy: a clinical perspective.
Sonneville R, Benghanem S, Jeantin L, de Montmollin E, Doman M, Gaudemer A, Thy M, Timsit JF
Crit Care 2023 Oct 5;27(1):386. doi: 10.1186/s13054-023-04655-8. PMID: 37798769Free PMC Article
Sex-related differences in adult patients with status epilepticus: a seven-year two-center observation.
Baumann SM, De Stefano P, Kliem PSC, Grzonka P, Gebhard CE, Sarbu OE, De Marchis GM, Hunziker S, Rüegg S, Kleinschmidt A, Pugin J, Quintard H, Marsch S, Seeck M, Sutter R
Crit Care 2023 Aug 5;27(1):308. doi: 10.1186/s13054-023-04592-6. PMID: 37543625Free PMC Article
Surgery for epilepsy.
West S, Nevitt SJ, Cotton J, Gandhi S, Weston J, Sudan A, Ramirez R, Newton R
Cochrane Database Syst Rev 2019 Jun 25;6(6):CD010541. doi: 10.1002/14651858.CD010541.pub3. PMID: 31237346Free PMC Article
Surgery for epilepsy.
West S, Nolan SJ, Cotton J, Gandhi S, Weston J, Sudan A, Ramirez R, Newton R
Cochrane Database Syst Rev 2015 Jul 1;(7):CD010541. doi: 10.1002/14651858.CD010541.pub2. PMID: 26130264
Landau-Kleffner syndrome is not an eponymic badge of ignorance.
Hirsch E, Valenti MP, Rudolf G, Seegmuller C, de Saint Martin A, Maquet P, Wioland N, Metz-Lutz MN, Marescaux C, Arzimanoglou A
Epilepsy Res 2006 Aug;70 Suppl 1:S239-47. Epub 2006 Jun 27 doi: 10.1016/j.eplepsyres.2006.02.010. PMID: 16806832

Clinical prediction guides

Clinical spectrum of pediatric drug refractory epilepsy secondary to parieto-occipital gliosis.
Ray S, Kenchaiah R, Asranna A, Padmanabha H, Kulanthaivelu K, Mundlamuri RC, Viswanathan LG, Chatterjee A, Thennarasu K, Sinha S
Epilepsy Res 2021 Dec;178:106804. Epub 2021 Nov 2 doi: 10.1016/j.eplepsyres.2021.106804. PMID: 34753071
Sensitivity of magnetoencephalography as a diagnostic tool for epilepsy: a prospective study.
Koster I, Ossenblok P, Brekelmans GJ, van der Linden I, Hillebrand A, Wijnen BF, Colon AJ
Epileptic Disord 2020 Jun 1;22(3):264-272. doi: 10.1684/epd.2020.1160. PMID: 32554358
Surgery for epilepsy.
West S, Nevitt SJ, Cotton J, Gandhi S, Weston J, Sudan A, Ramirez R, Newton R
Cochrane Database Syst Rev 2019 Jun 25;6(6):CD010541. doi: 10.1002/14651858.CD010541.pub3. PMID: 31237346Free PMC Article
Surgery for epilepsy.
West S, Nolan SJ, Cotton J, Gandhi S, Weston J, Sudan A, Ramirez R, Newton R
Cochrane Database Syst Rev 2015 Jul 1;(7):CD010541. doi: 10.1002/14651858.CD010541.pub2. PMID: 26130264
Neurophysiology of spasms.
Vigevano F, Fusco L, Pachatz C
Brain Dev 2001 Nov;23(7):467-72. doi: 10.1016/s0387-7604(01)00284-4. PMID: 11701240

Recent systematic reviews

Surgery for epilepsy.
West S, Nevitt SJ, Cotton J, Gandhi S, Weston J, Sudan A, Ramirez R, Newton R
Cochrane Database Syst Rev 2019 Jun 25;6(6):CD010541. doi: 10.1002/14651858.CD010541.pub3. PMID: 31237346Free PMC Article
Surgery for epilepsy.
West S, Nolan SJ, Cotton J, Gandhi S, Weston J, Sudan A, Ramirez R, Newton R
Cochrane Database Syst Rev 2015 Jul 1;(7):CD010541. doi: 10.1002/14651858.CD010541.pub2. PMID: 26130264

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