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Focal behavior arrest seizure

MedGen UID:
869080
•Concept ID:
C4023498
•
Disease or Syndrome
Synonyms: Focal behaviour arrest seizure; Focal hypokinetic seizure; Focal onset behavior arrest epileptic seizure; Focal onset behavior arrest seizure; Focal-onset behavior arrest epileptic seizure; Hypokinetic seizure; Hypokinetic seizures; Localised seizure with behavioral arrest; Localised seizure with behavioural arrest; Localized seizure with behavioral arrest; Partial hypokinetic seizure; Partial seizure with behavior arrest; Partial seizure with behaviour arrest
SNOMED CT: Focal onset behavior arrest epileptic seizure (1281831009); Focal onset behavior arrest seizure (1281831009); Focal-onset behavior arrest epileptic seizure (1281831009); Focal behavior arrest seizure (1281831009)
 
HPO: HP:0011173

Definition

A type of focal non-motor seizure characterized by an arrest or pause of activities, freezing, or immobilization as the predominant semiological feature throughout the seizure. [from HPO]

Term Hierarchy

CClinical test,  RResearch test,  OOMIM,  GGeneReviews,  VClinVar  
  • CROGVFocal behavior arrest seizure

Professional guidelines

PubMed

Evaluation of absences and myoclonic seizures in adults with genetic (idiopathic) generalized epilepsy: a comparison between self-evaluation and objective evaluation based on home video-EEG telemetry.
Elmali AD, Begley K, Chester H, Cooper J, Moreira C, Sharma S, Whelan A, Leschziner G, Richardson MP, Stern W, Koutroumanidis M
Epileptic Disord 2021 Oct 1;23(5):719-732. doi: 10.1684/epd.2021.1325. PMID: 34612815
Management and long-term outcome in patients presenting with ictal asystole or bradycardia.
Strzelczyk A, Cenusa M, Bauer S, Hamer HM, Mothersill IW, Grunwald T, Hillenbrand B, Ebner A, Steinhoff BJ, Krämer G, Rosenow F
Epilepsia 2011 Jun;52(6):1160-7. Epub 2011 Feb 14 doi: 10.1111/j.1528-1167.2010.02961.x. PMID: 21320110
The role of nonpharmaceutic conservative interventions in the treatment and secondary prevention of epilepsy.
Wolf P
Epilepsia 2002;43 Suppl 9:2-5. doi: 10.1046/j.1528-1157.43.s.9.2.x. PMID: 12383271

Recent clinical studies

Etiology

Panayiotopoulos syndrome: Unusual clinical manifestations.
Semprino M, Galicchio S, Espeche A, Cersosimo R, Chacon S, Gamboni B, Adi J, Fasulo L, Fortini S, Cachia P, Gallo A, Caraballo RH
Epilepsy Behav 2022 Mar;128:108552. Epub 2022 Jan 18 doi: 10.1016/j.yebeh.2022.108552. PMID: 35063695
Self-limited epilepsy of childhood with affective seizures: A well-defined epileptic syndrome?
Espeche A, Galicchio S, Cersósimo R, Chacon S, Gamboni B, Adi J, Fasulo L, Semprino M, Fortini S, Cachia P, Caraballo RH
Epilepsy Behav 2021 Apr;117:107885. Epub 2021 Mar 11 doi: 10.1016/j.yebeh.2021.107885. PMID: 33714932
The ILAE classification of seizures and the epilepsies: Modification for seizures in the neonate. Position paper by the ILAE Task Force on Neonatal Seizures.
Pressler RM, Cilio MR, Mizrahi EM, Moshé SL, Nunes ML, Plouin P, Vanhatalo S, Yozawitz E, de Vries LS, Puthenveettil Vinayan K, Triki CC, Wilmshurst JM, Yamamoto H, Zuberi SM
Epilepsia 2021 Mar;62(3):615-628. Epub 2021 Feb 1 doi: 10.1111/epi.16815. PMID: 33522601
Seizure ending signs in patients with dyscognitive focal seizures.
Gavvala JR, Gerard EE, Macken M, Schuele SU
Epileptic Disord 2015 Sep;17(3):255-62. doi: 10.1684/epd.2015.0763. PMID: 26271680
The epidemiology of methamphetamine use and harm in Australia.
Degenhardt L, Roxburgh A, Black E, Bruno R, Campbell G, Kinner S, Fetherston J
Drug Alcohol Rev 2008 May;27(3):243-52. doi: 10.1080/09595230801950572. PMID: 18368605

Diagnosis

"Generalized-to-focal" epilepsy: stereotactic EEG and high-frequency oscillation patterns.
von Ellenrieder N, Dubeau F, Dudley RWR, Dufresne D, Gotman J, Baillet S, Moreau JT, Bernasconi N, Bernasconi A, Osterman B, Simard-Tremblay E, Myers KA
Epileptic Disord 2022 Dec 1;24(6):1087-1094. doi: 10.1684/epd.2022.1489. PMID: 36190316
Panayiotopoulos syndrome: Unusual clinical manifestations.
Semprino M, Galicchio S, Espeche A, Cersosimo R, Chacon S, Gamboni B, Adi J, Fasulo L, Fortini S, Cachia P, Gallo A, Caraballo RH
Epilepsy Behav 2022 Mar;128:108552. Epub 2022 Jan 18 doi: 10.1016/j.yebeh.2022.108552. PMID: 35063695
The ILAE classification of seizures and the epilepsies: Modification for seizures in the neonate. Position paper by the ILAE Task Force on Neonatal Seizures.
Pressler RM, Cilio MR, Mizrahi EM, Moshé SL, Nunes ML, Plouin P, Vanhatalo S, Yozawitz E, de Vries LS, Puthenveettil Vinayan K, Triki CC, Wilmshurst JM, Yamamoto H, Zuberi SM
Epilepsia 2021 Mar;62(3):615-628. Epub 2021 Feb 1 doi: 10.1111/epi.16815. PMID: 33522601
The new classification of seizures: an overview for the general physician.
Liyanagedera S, Williams RP
J R Coll Physicians Edinb 2017 Dec;47(4):336-338. doi: 10.4997/JRCPE.2017.406. PMID: 29537403
Operational classification of seizure types by the International League Against Epilepsy: Position Paper of the ILAE Commission for Classification and Terminology.
Fisher RS, Cross JH, French JA, Higurashi N, Hirsch E, Jansen FE, Lagae L, Moshé SL, Peltola J, Roulet Perez E, Scheffer IE, Zuberi SM
Epilepsia 2017 Apr;58(4):522-530. Epub 2017 Mar 8 doi: 10.1111/epi.13670. PMID: 28276060

Therapy

Anti-GABA-A Receptor Antibody-Mediated Epilepsia Partialis Continua After Treatment With Alemtuzumab: A Case Report.
Ratuszny D, Skripuletz T, Stüber T, Valizada E, Gehring K, Ertl P, Müller JA, Wattjes MP, Feuerhake F, Sühs KW
Neurol Neuroimmunol Neuroinflamm 2023 Jul;10(4) Epub 2023 May 18 doi: 10.1212/NXI.0000000000200123. PMID: 37202183Free PMC Article
Functional definition of seizure provides new insight into post-traumatic epileptogenesis.
D'Ambrosio R, Hakimian S, Stewart T, Verley DR, Fender JS, Eastman CL, Sheerin AH, Gupta P, Diaz-Arrastia R, Ojemann J, Miller JW
Brain 2009 Oct;132(Pt 10):2805-21. Epub 2009 Sep 15 doi: 10.1093/brain/awp217. PMID: 19755519Free PMC Article
Dravet syndrome: from electroclinical characteristics to molecular biology.
Arzimanoglou A
Epilepsia 2009 Sep;50 Suppl 8:3-9. doi: 10.1111/j.1528-1167.2009.02228.x. PMID: 19702726
The epidemiology of methamphetamine use and harm in Australia.
Degenhardt L, Roxburgh A, Black E, Bruno R, Campbell G, Kinner S, Fetherston J
Drug Alcohol Rev 2008 May;27(3):243-52. doi: 10.1080/09595230801950572. PMID: 18368605
The development of epilepsy in the paediatric brain.
Velísková J, Velísek L, Sperber EF, Haas KZ, Moshé SL
Seizure 1994 Dec;3(4):263-70. doi: 10.1016/s1059-1311(05)80173-6. PMID: 7894836

Prognosis

Self-limited epilepsy with centro-temporal spikes: A study of 46 patients with unusual clinical manifestations.
Galicchio S, Espeche A, Cersosimo R, Chacon S, Gamboni B, Adi J, Fasulo L, Semprino M, Fortini S, Cachia P, Caraballo RH
Epilepsy Res 2021 Jan;169:106507. Epub 2020 Nov 21 doi: 10.1016/j.eplepsyres.2020.106507. PMID: 33296810
Seizures with paroxysmal arousals in sleep-related hypermotor epilepsy (SHE): Dissecting epilepsy from NREM parasomnias.
Loddo G, Baldassarri L, Zenesini C, Licchetta L, Bisulli F, Cirignotta F, Mondini S, Tinuper P, Provini F
Epilepsia 2020 Oct;61(10):2194-2202. Epub 2020 Sep 19 doi: 10.1111/epi.16659. PMID: 32949468
Prevalence, clinical characteristics, and seizure outcomes of epilepsy due to calcific clinical stage of neurocysticercosis: Study in a rural community in south India.
Murthy JMK, Seshadri V
Epilepsy Behav 2019 Sep;98(Pt A):168-172. Epub 2019 Jul 31 doi: 10.1016/j.yebeh.2019.07.024. PMID: 31376678
Clinical and Electrographic Correlates of Bilateral Independent Periodic Discharges.
Freund B, Gugger JJ, Reynolds A, Tatum WO, Claassen J, Kaplan PW
J Clin Neurophysiol 2018 May;35(3):234-241. doi: 10.1097/WNP.0000000000000472. PMID: 29547472
The brain-heart connection: implications for understanding sudden unexpected death in epilepsy.
Scorza FA, Arida RM, Cysneiros RM, Terra VC, Sonoda EY, de Albuquerque M, Cavalheiro EA
Cardiol J 2009;16(5):394-9. PMID: 19753516

Clinical prediction guides

Self-limited epilepsy of childhood with affective seizures: A well-defined epileptic syndrome?
Espeche A, Galicchio S, Cersósimo R, Chacon S, Gamboni B, Adi J, Fasulo L, Semprino M, Fortini S, Cachia P, Caraballo RH
Epilepsy Behav 2021 Apr;117:107885. Epub 2021 Mar 11 doi: 10.1016/j.yebeh.2021.107885. PMID: 33714932
Prevalence, clinical characteristics, and seizure outcomes of epilepsy due to calcific clinical stage of neurocysticercosis: Study in a rural community in south India.
Murthy JMK, Seshadri V
Epilepsy Behav 2019 Sep;98(Pt A):168-172. Epub 2019 Jul 31 doi: 10.1016/j.yebeh.2019.07.024. PMID: 31376678
The prevalence and clinical features of epileptic seizures in a memory clinic population.
Baker J, Libretto T, Henley W, Zeman A
Seizure 2019 Oct;71:83-92. Epub 2019 Jun 12 doi: 10.1016/j.seizure.2019.06.016. PMID: 31226566
Epileptological aspects of juvenile neuronal ceroid lipofuscinosis (CLN3 disease) through the lifespan.
Arntsen V, Strandheim J, Helland IB, Sand T, Brodtkorb E
Epilepsy Behav 2019 May;94:59-64. Epub 2019 Mar 16 doi: 10.1016/j.yebeh.2019.02.020. PMID: 30884409
Clinical and Electrographic Correlates of Bilateral Independent Periodic Discharges.
Freund B, Gugger JJ, Reynolds A, Tatum WO, Claassen J, Kaplan PW
J Clin Neurophysiol 2018 May;35(3):234-241. doi: 10.1097/WNP.0000000000000472. PMID: 29547472

Recent systematic reviews

Systematic review of EEG findings in 617 patients diagnosed with COVID-19.
Antony AR, Haneef Z
Seizure 2020 Dec;83:234-241. Epub 2020 Oct 19 doi: 10.1016/j.seizure.2020.10.014. PMID: 33121875Free PMC Article

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