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Agenesis of permanent maxillary lateral incisor

MedGen UID:
869147
•Concept ID:
C4023567
•
Finding
Synonyms: Absence of permanent maxillary lateral incisor; Agenesis of permanent upper lateral incisor; Failure of development of permanent maxillary lateral incisor; Failure of development of permanent upper lateral incisor; Missing permanent maxillary lateral incisor; Missing permanent upper lateral incisor
 
HPO: HP:0011050

Definition

Agenesis of one or more upper lateral secondary incisor. [from HPO]

Term Hierarchy

CClinical test,  RResearch test,  OOMIM,  GGeneReviews,  VClinVar  
  • CROGVAgenesis of permanent maxillary lateral incisor

Professional guidelines

PubMed

Utilising Digital Dentistry for the Management of Patients With Hypodontia of Lateral Incisers.
Pirmohamed S, Bomfim DI
Prim Dent J 2018 Summer;7(2):50-5. PMID: 30095883
Hypodontia: An Update on Its Etiology, Classification, and Clinical Management.
Al-Ani AH, Antoun JS, Thomson WM, Merriman TR, Farella M
Biomed Res Int 2017;2017:9378325. Epub 2017 Mar 19 doi: 10.1155/2017/9378325. PMID: 28401166Free PMC Article
Pattern of agenesis in the primary dentition: a radiographic study of 193 cases.
Daugaard-Jensen J, Nodal M, Kjaer I
Int J Paediatr Dent 1997 Mar;7(1):3-7. doi: 10.1111/j.1365-263x.1997.tb00265.x. PMID: 9524465

Recent clinical studies

Etiology

Patterns of nonsyndromic tooth agenesis and sexual dimorphism.
Kanchanasevee C, Chantarangsu S, Pittayapat P, Porntaveetus T
BMC Oral Health 2023 Jan 23;23(1):37. doi: 10.1186/s12903-023-02753-1. PMID: 36691053Free PMC Article
Skeletal and dentoalveolar characteristics of maxillary lateral incisor agenesis patients: a comparative cross-sectional study.
Tageldin MA, Yacout YM, Marzouk ES
BMC Oral Health 2022 Dec 15;22(1):608. doi: 10.1186/s12903-022-02656-7. PMID: 36522742Free PMC Article
Position and Eruption of Permanent Maxillary Canines in Cases of Maxillary Lateral Incisor Agenesis in Mixed Dentition.
Lamas C, Lavall A, Pinho T
J Clin Pediatr Dent 2018;42(3):240-246. Epub 2018 Apr 26 doi: 10.17796/1053-4628-42.3.14. PMID: 29698144
Prosthetic replacement vs space closure for maxillary lateral incisor agenesis: A systematic review.
Silveira GS, de Almeida NV, Pereira DM, Mattos CT, Mucha JN
Am J Orthod Dentofacial Orthop 2016 Aug;150(2):228-37. doi: 10.1016/j.ajodo.2016.01.018. PMID: 27476355
Prevalence of peg-shaped maxillary permanent lateral incisors: A meta-analysis.
Hua F, He H, Ngan P, Bouzid W
Am J Orthod Dentofacial Orthop 2013 Jul;144(1):97-109. doi: 10.1016/j.ajodo.2013.02.025. PMID: 23810051

Diagnosis

Molar incisor hypomineralization: Analysis of asymmetry of lesions.
Biondi AM, Córtese SG, Babino L, Toscano MA
Acta Odontol Latinoam 2019 Apr 1;32(1):44-48. PMID: 31206574
Prevalence and patterns of permanent tooth agenesis in individuals with Down syndrome: a meta-analysis.
Palaska PK, Antonarakis GS
Eur J Oral Sci 2016 Aug;124(4):317-28. Epub 2016 Jun 17 doi: 10.1111/eos.12282. PMID: 27311636
Prevalence and distribution of anomalies of permanent dentition in 9584 Japanese high school students.
Hagiwara Y, Uehara T, Narita T, Tsutsumi H, Nakabayashi S, Araki M
Odontology 2016 Sep;104(3):380-9. Epub 2015 Nov 26 doi: 10.1007/s10266-015-0225-2. PMID: 26612080
A study of prevalence and distribution of tooth agenesis.
Bozga A, Stanciu RP, Mănuc D
J Med Life 2014 Oct-Dec;7(4):551-4. PMID: 25713620Free PMC Article
Agenesis of maxillary lateral incisors: a global overview of the clinical problem.
Kavadia S, Papadiochou S, Papadiochos I, Zafiriadis L
Orthodontics (Chic.) 2011 Winter;12(4):296-317. PMID: 22299104

Therapy

Prosthetic replacement vs space closure for maxillary lateral incisor agenesis: A systematic review.
Silveira GS, de Almeida NV, Pereira DM, Mattos CT, Mucha JN
Am J Orthod Dentofacial Orthop 2016 Aug;150(2):228-37. doi: 10.1016/j.ajodo.2016.01.018. PMID: 27476355
Clinical and Radiographic Evaluation of a Small-Diameter Dental Implant Used for the Restoration of Patients with Permanent Tooth Agenesis (Hypodontia) in the Maxillary Lateral Incisor and Mandibular Incisor Regions: A 36-Month Follow-Up.
King P, Maiorana C, Luthardt RG, Sondell K, Øland J, Galindo-Moreno P, Nilsson P
Int J Prosthodont 2016 Mar-Apr;29(2):147-53. doi: 10.11607/ijp.4444. PMID: 26929953
Prevalence of peg-shaped maxillary permanent lateral incisors: A meta-analysis.
Hua F, He H, Ngan P, Bouzid W
Am J Orthod Dentofacial Orthop 2013 Jul;144(1):97-109. doi: 10.1016/j.ajodo.2013.02.025. PMID: 23810051
Patterns of third-molar agenesis and associated dental anomalies in an orthodontic population.
Celikoglu M, Bayram M, Nur M
Am J Orthod Dentofacial Orthop 2011 Dec;140(6):856-60. doi: 10.1016/j.ajodo.2011.05.021. PMID: 22133951
Prevalence of hypodontia and developmental malformation of permanent teeth in Saudi Arabian schoolchildren.
al-Emran S
Br J Orthod 1990 May;17(2):115-8. doi: 10.1179/bjo.17.2.115. PMID: 2192761

Prognosis

Hypodontia: An Update on Its Etiology, Classification, and Clinical Management.
Al-Ani AH, Antoun JS, Thomson WM, Merriman TR, Farella M
Biomed Res Int 2017;2017:9378325. Epub 2017 Mar 19 doi: 10.1155/2017/9378325. PMID: 28401166Free PMC Article
Prevalence and patterns of permanent tooth agenesis in individuals with Down syndrome: a meta-analysis.
Palaska PK, Antonarakis GS
Eur J Oral Sci 2016 Aug;124(4):317-28. Epub 2016 Jun 17 doi: 10.1111/eos.12282. PMID: 27311636
Clinical and Radiographic Evaluation of a Small-Diameter Dental Implant Used for the Restoration of Patients with Permanent Tooth Agenesis (Hypodontia) in the Maxillary Lateral Incisor and Mandibular Incisor Regions: A 36-Month Follow-Up.
King P, Maiorana C, Luthardt RG, Sondell K, Øland J, Galindo-Moreno P, Nilsson P
Int J Prosthodont 2016 Mar-Apr;29(2):147-53. doi: 10.11607/ijp.4444. PMID: 26929953
Retrospective Study of Association between Displacement of Maxillary Canine and Tooth Agenesis.
Jang E, Lee K, An S, Song J, Ra J
J Clin Pediatr Dent 2015 Fall;39(5):488-92. doi: 10.17796/1053-4628-39.5.488. PMID: 26551375
Permanent Tooth Agenesis and Maxillary Hypoplasia in Patients with Unilateral Cleft Lip and Palate.
Antonarakis GS, Fisher DM
Plast Reconstr Surg 2015 Nov;136(5):648e-656e. doi: 10.1097/PRS.0000000000001694. PMID: 26505722

Clinical prediction guides

Patterns of nonsyndromic tooth agenesis and sexual dimorphism.
Kanchanasevee C, Chantarangsu S, Pittayapat P, Porntaveetus T
BMC Oral Health 2023 Jan 23;23(1):37. doi: 10.1186/s12903-023-02753-1. PMID: 36691053Free PMC Article
Molar incisor hypomineralization: Analysis of asymmetry of lesions.
Biondi AM, Córtese SG, Babino L, Toscano MA
Acta Odontol Latinoam 2019 Apr 1;32(1):44-48. PMID: 31206574
Hypodontia: An Update on Its Etiology, Classification, and Clinical Management.
Al-Ani AH, Antoun JS, Thomson WM, Merriman TR, Farella M
Biomed Res Int 2017;2017:9378325. Epub 2017 Mar 19 doi: 10.1155/2017/9378325. PMID: 28401166Free PMC Article
Prosthetic replacement vs space closure for maxillary lateral incisor agenesis: A systematic review.
Silveira GS, de Almeida NV, Pereira DM, Mattos CT, Mucha JN
Am J Orthod Dentofacial Orthop 2016 Aug;150(2):228-37. doi: 10.1016/j.ajodo.2016.01.018. PMID: 27476355
Prevalence of hypodontia and developmental malformation of permanent teeth in Saudi Arabian schoolchildren.
al-Emran S
Br J Orthod 1990 May;17(2):115-8. doi: 10.1179/bjo.17.2.115. PMID: 2192761

Recent systematic reviews

Atypical Radicular Anatomy in Permanent Human Teeth: A Systematic Review.
Nino-Barrera J, Alzate-Mendoza D, Olaya-Abril C, Gamboa-Martinez LF, Guamán-Laverde M, Lagos-Rosero N, Romero-Diaz AC, Duran N, Vanegas-Hoyose L
Crit Rev Biomed Eng 2022;50(1):19-34. doi: 10.1615/CritRevBiomedEng.2022043742. PMID: 35997108
Association between superior labial frenum and maxillary midline diastema - a systematic review.
Tadros S, Ben-Dov T, Catháin ÉÓ, Anglin C, April MM
Int J Pediatr Otorhinolaryngol 2022 May;156:111063. Epub 2022 Feb 26 doi: 10.1016/j.ijporl.2022.111063. PMID: 35248905
Orthodontic canine substitution vs. implant-supported prosthetic replacement for maxillary permanent lateral incisor agenesis: A systematic review.
Šikšnelytė J, Guntulytė R, Lopatienė K
Stomatologija 2021;23(4):106-113. PMID: 35635522
Prosthetic replacement vs space closure for maxillary lateral incisor agenesis: A systematic review.
Silveira GS, de Almeida NV, Pereira DM, Mattos CT, Mucha JN
Am J Orthod Dentofacial Orthop 2016 Aug;150(2):228-37. doi: 10.1016/j.ajodo.2016.01.018. PMID: 27476355
Management of non-syndromic double tooth affecting permanent maxillary central incisors: a systematic review.
Smail-Faugeron V, Terradot J, Muller Bolla M, Courson F
BMJ Case Rep 2016 Jun 15;2016 doi: 10.1136/bcr-2016-215482. PMID: 27307427Free PMC Article

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