U.S. flag

An official website of the United States government

Format

Send to:

Choose Destination

Prominent nasal septum

MedGen UID:
870759
Concept ID:
C4025216
Finding
Synonyms: Low hanging nasal septum; Low hanging septum of nose; Prominent septum of nose; Visible nasal septum; Visible septum of nose
 
HPO: HP:0005322

Term Hierarchy

CClinical test,  RResearch test,  OOMIM,  GGeneReviews,  VClinVar  
  • CROGVProminent nasal septum

Conditions with this feature

Zimmermann-Laband syndrome 2
MedGen UID:
897567
Concept ID:
C4225321
Disease or Syndrome
Zimmerman-Laband syndrome is a developmental disorder characterized by facial dysmorphism with gingival enlargement, bulbous soft nose, and think floppy ears, nail aplasia or hypoplasia, hypertrichosis, joint hypertextensibility, hepato(spleno)megaly, and impaired intellectual development with or without epilepsy (summary by Kortum et al., 2015). For a general phenotypic description and a discussion of genetic heterogeneity of Zimmermann-Laband syndrome, see ZLS1 (135500).

Recent clinical studies

Etiology

Peng S, Huang X, Gu T, Liang Y, Yu L, Wu J, Guo Z, Lin J
J Craniofac Surg 2023 Oct 1;34(7):2082-2086. Epub 2023 May 31 doi: 10.1097/SCS.0000000000009391. PMID: 37254241
Kaya H, Kurt E, Koparal M, Tibilli H, Hosoglu Y, Kafadar S, Suner A, Türkmen S
Braz J Otorhinolaryngol 2022 Jul-Aug;88(4):589-593. Epub 2020 Sep 26 doi: 10.1016/j.bjorl.2020.08.004. PMID: 33067133Free PMC Article
Afolabi OA, Alabi BS
Niger J Med 2010 Oct-Dec;19(4):348-51. doi: 10.4314/njm.v19i4.61955. PMID: 21526619
Higuera S, Lee EI, Cole P, Hollier LH Jr, Stal S
Plast Reconstr Surg 2007 Dec;120(7 Suppl 2):64S-75S. doi: 10.1097/01.prs.0000260722.91183.50. PMID: 18090730
Mehta U, Brunworth J, Lewis RA, Sindwani R
Am J Rhinol 2007 Jan-Feb;21(1):55-8. doi: 10.2500/ajr.2007.21.2989. PMID: 17283562

Diagnosis

Lou ZC, Lou ZH
J Laryngol Otol 2019 Apr;133(4):309-312. Epub 2019 Apr 1 doi: 10.1017/S0022215119000562. PMID: 30929656
Aslan G, Uzun L, Ugur MB, Uckurt YS, Sagun OF, Yazicilar O
Am J Rhinol Allergy 2013 Jul-Aug;27(4):255-9. doi: 10.2500/ajra.2013.27.3918. PMID: 23883804
Higuera S, Lee EI, Cole P, Hollier LH Jr, Stal S
Plast Reconstr Surg 2007 Dec;120(7 Suppl 2):64S-75S. doi: 10.1097/01.prs.0000260722.91183.50. PMID: 18090730
Mehta U, Brunworth J, Lewis RA, Sindwani R
Am J Rhinol 2007 Jan-Feb;21(1):55-8. doi: 10.2500/ajr.2007.21.2989. PMID: 17283562
Touraine RL, Zeniou M, Hanauer A
Eur J Pediatr 2002 Apr;161(4):179-87. doi: 10.1007/s00431-001-0904-6. PMID: 12014383

Therapy

Kaya H, Kurt E, Koparal M, Tibilli H, Hosoglu Y, Kafadar S, Suner A, Türkmen S
Braz J Otorhinolaryngol 2022 Jul-Aug;88(4):589-593. Epub 2020 Sep 26 doi: 10.1016/j.bjorl.2020.08.004. PMID: 33067133Free PMC Article
Ferraz MBJ, Sella GCP
Facial Plast Surg 2021 Feb;37(1):45-52. Epub 2021 Mar 14 doi: 10.1055/s-0041-1725154. PMID: 33715148
Davis RE
Facial Plast Surg 2012 Jun;28(3):294-302. Epub 2012 Jun 21 doi: 10.1055/s-0032-1312700. PMID: 22723230
Amin M, Glynn F, Phelan S, Sheahan P, Crotty P, McShane D
Clin Otolaryngol 2007 Jun;32(3):197-9. doi: 10.1111/j.1365-2273.2007.01409.x. PMID: 17550512
Holt GR, Garner ET, McLarey D
Otolaryngol Clin North Am 1987 Nov;20(4):853-76. PMID: 3320872

Prognosis

Feng Z, Si M, Fan H, Zhang Y, Yuan R, Hao Z
Clin Oral Investig 2023 Dec 22;28(1):14. doi: 10.1007/s00784-023-05430-3. PMID: 38129341Free PMC Article
Greene BJ, Topf MC, Meyers SP, Man LX
JAMA Otolaryngol Head Neck Surg 2014 Feb;140(2):177-8. doi: 10.1001/jamaoto.2013.5885. PMID: 24309710
Aslan G, Uzun L, Ugur MB, Uckurt YS, Sagun OF, Yazicilar O
Am J Rhinol Allergy 2013 Jul-Aug;27(4):255-9. doi: 10.2500/ajra.2013.27.3918. PMID: 23883804
Afolabi OA, Alabi BS
Niger J Med 2010 Oct-Dec;19(4):348-51. doi: 10.4314/njm.v19i4.61955. PMID: 21526619
Mehta U, Brunworth J, Lewis RA, Sindwani R
Am J Rhinol 2007 Jan-Feb;21(1):55-8. doi: 10.2500/ajr.2007.21.2989. PMID: 17283562

Clinical prediction guides

Feng Z, Si M, Fan H, Zhang Y, Yuan R, Hao Z
Clin Oral Investig 2023 Dec 22;28(1):14. doi: 10.1007/s00784-023-05430-3. PMID: 38129341Free PMC Article
Kaya H, Kurt E, Koparal M, Tibilli H, Hosoglu Y, Kafadar S, Suner A, Türkmen S
Braz J Otorhinolaryngol 2022 Jul-Aug;88(4):589-593. Epub 2020 Sep 26 doi: 10.1016/j.bjorl.2020.08.004. PMID: 33067133Free PMC Article
Liu L, Bu Z, Fan J, Tian J, Gan C, Yang Z, Jiao H
Plast Reconstr Surg 2017 Dec;140(6):1163-1166. doi: 10.1097/PRS.0000000000003874. PMID: 28806289
Aslan G, Uzun L, Ugur MB, Uckurt YS, Sagun OF, Yazicilar O
Am J Rhinol Allergy 2013 Jul-Aug;27(4):255-9. doi: 10.2500/ajra.2013.27.3918. PMID: 23883804
Hinderer UT
Clin Plast Surg 1991 Jan;18(1):87-105. PMID: 2015752

Supplemental Content

Table of contents

    Clinical resources

    Practice guidelines

    • Bookshelf
      See practice and clinical guidelines in NCBI Bookshelf. The search results may include broader topics and may not capture all published guidelines. See the FAQ for details.

    Consumer resources

    Recent activity

    Your browsing activity is empty.

    Activity recording is turned off.

    Turn recording back on

    See more...