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Abnormality of the nasolabial region

MedGen UID:
870766
•Concept ID:
C4025223
•
Anatomical Abnormality
Synonyms: Anomaly of the nasolabial region; Deformity of the nasolabial region; Malformation of the nasolabial region
 
HPO: HP:0005289

Term Hierarchy

CClinical test,  RResearch test,  OOMIM,  GGeneReviews,  VClinVar  
  • CROGVAbnormality of the nasolabial region

Professional guidelines

PubMed

Aesthetic Assessment of Infants With Different Cleft Types Before, During, and After Orthopedic Treatment.
Nur Yilmaz RB, Germeç Çakan D, Nalbantgil D
J Craniofac Surg 2018 Nov;29(8):2081-2087. doi: 10.1097/SCS.0000000000004888. PMID: 30334916
Photometric evaluation of bilateral cleft lip and palate patients after primary columella lengthening.
Meazzini MC, Rossetti G, Morabito A, Garattini G, Brusati R
Cleft Palate Craniofac J 2010 Jan;47(1):58-65. doi: 10.1597/08-240.1. PMID: 19860518
Nasal malformations associated with unilateral cleft lip. Accurate diagnosis and management.
Talmant JC
Scand J Plast Reconstr Surg Hand Surg 1993 Sep;27(3):183-91. doi: 10.3109/02844319309078110. PMID: 8272769

Recent clinical studies

Etiology

Is the Nasolabial Region Symmetric in Individuals With Cleft Lip and Palate?
Dindaroglu F, Dogan E, Dogan S
Cleft Palate Craniofac J 2024 Jan;61(1):12-19. Epub 2022 Aug 1 doi: 10.1177/10556656221116535. PMID: 35912442
3D assessment of the nasolabial region in cleft models comparing an intraoral and a facial scanner to a validated baseline.
Olmos M, Matta R, Buchbender M, Jaeckel F, Nobis CP, Weber M, Kesting M, Lutz R
Sci Rep 2023 Jul 27;13(1):12216. doi: 10.1038/s41598-023-39352-7. PMID: 37500683Free PMC Article
The effect of botulinum toxin A in unilateral cleft lip scar: comparison of results with different sites of injection.
Lu TC, Bhandari K, Yao CF, Chen PK
Int J Oral Maxillofac Surg 2022 Jul;51(7):900-905. Epub 2022 Jan 7 doi: 10.1016/j.ijom.2021.12.007. PMID: 35012827
Evaluation of nasolabial aesthetics by different groups in operated unilateral cleft lip and palate.
Dogan E, Tiftikcioglu Y, Dogan S
J Stomatol Oral Maxillofac Surg 2020 Dec;121(6):672-679. Epub 2020 Jan 30 doi: 10.1016/j.jormas.2020.01.005. PMID: 32007634
A Novel Hypothesis of Visual Loss Secondary to Cosmetic Facial Filler Injection.
Li X, Du L, Lu JJ
Ann Plast Surg 2015 Sep;75(3):258-60. doi: 10.1097/SAP.0000000000000572. PMID: 26207560Free PMC Article

Diagnosis

Cleft Lip and Palate in Ectodermal Dysplasia.
Ganske IM, Irwin T, Langa O, Upton J 3rd, Tan WH, Mulliken JB
Cleft Palate Craniofac J 2021 Feb;58(2):237-243. Epub 2020 Aug 30 doi: 10.1177/1055665620949124. PMID: 32864997
Evaluation of nasolabial aesthetics by different groups in operated unilateral cleft lip and palate.
Dogan E, Tiftikcioglu Y, Dogan S
J Stomatol Oral Maxillofac Surg 2020 Dec;121(6):672-679. Epub 2020 Jan 30 doi: 10.1016/j.jormas.2020.01.005. PMID: 32007634
Identification of a novel pathogenic mutation of the MYH3 gene in a family with distal arthrogryposis type 2B.
Wang WB, Kong LC, Zuo RT, Kang QL
Mol Med Rep 2020 Jan;21(1):438-444. Epub 2019 Nov 15 doi: 10.3892/mmr.2019.10820. PMID: 31746383
Assessment of regional asymmetry of the face before and after surgical correction of unilateral cleft lip.
Al-Rudainy D, Ju X, Stanton S, Mehendale FV, Ayoub A
J Craniomaxillofac Surg 2018 Jun;46(6):974-978. Epub 2018 Apr 6 doi: 10.1016/j.jcms.2018.03.023. PMID: 29752048
Anthropometry for syndromology.
Lakshminarayana P, Janardhan K, David HS
Indian J Pediatr 1991 Mar-Apr;58(2):253-8. doi: 10.1007/BF02751131. PMID: 1879907

Therapy

The effect of botulinum toxin A in unilateral cleft lip scar: comparison of results with different sites of injection.
Lu TC, Bhandari K, Yao CF, Chen PK
Int J Oral Maxillofac Surg 2022 Jul;51(7):900-905. Epub 2022 Jan 7 doi: 10.1016/j.ijom.2021.12.007. PMID: 35012827
Judgment of Nasolabial Esthetics in Cleft Lip and Palate Is Not Influenced by Overall Facial Attractiveness.
Kocher K, Kowalski P, Kolokitha OE, Katsaros C, Fudalej PS
Cleft Palate Craniofac J 2016 May;53(3):e45-52. Epub 2015 May 1 doi: 10.1597/14-019. PMID: 25932752
A Novel Hypothesis of Visual Loss Secondary to Cosmetic Facial Filler Injection.
Li X, Du L, Lu JJ
Ann Plast Surg 2015 Sep;75(3):258-60. doi: 10.1097/SAP.0000000000000572. PMID: 26207560Free PMC Article
Nasolabial aesthetics.
Mitchell C, Oeltjen J, Panthaki Z, Thaller SR
J Craniofac Surg 2007 Jul;18(4):756-65. doi: 10.1097/scs.0b013e3180684360. PMID: 17667661
Suction-assisted lipectomy for lipodystrophy syndromes attributed to HIV-protease inhibitor use.
Wolfort FG, Cetrulo CL Jr, Nevarre DR
Plast Reconstr Surg 1999 Nov;104(6):1814-20; discussion 1821-2. PMID: 10541186

Prognosis

Cleft Lip and Palate in Ectodermal Dysplasia.
Ganske IM, Irwin T, Langa O, Upton J 3rd, Tan WH, Mulliken JB
Cleft Palate Craniofac J 2021 Feb;58(2):237-243. Epub 2020 Aug 30 doi: 10.1177/1055665620949124. PMID: 32864997
An Analysis of Aesthetic Refinements in 120 Secondary Cleft Rhinoplasties.
Kehrer A, Nijhuis THJ, Lonic D, Heidekrueger PI, Kehrer M, Taeger CD, Willemsen S, Prantl L, van der Meulen JJJNM
Ann Plast Surg 2019 Oct;83(4):429-435. doi: 10.1097/SAP.0000000000002045. PMID: 31524737
Dynamic Nasolabial Growth After Primary Surgery for Patients With Bilateral Cleft Lip: A Five-Year Follow-Up Study.
Wei Y, Zhong T, Yin X, Shi B, Zheng Q, Li J
J Oral Maxillofac Surg 2019 Oct;77(10):2125.e1-2125.e10. Epub 2019 May 30 doi: 10.1016/j.joms.2019.05.013. PMID: 31238020
Active Presurgical Infant Orthopedics for Unilateral Cleft Lip and Palate: Intercenter Outcome Comparison of Latham, Modified McNeil, and Nasoalveolar Molding.
Kornbluth M, Campbell RE, Daskalogiannakis J, Ross EJ, Glick PH, Russell KA, Doucet JC, Hathaway RR, Long RE Jr, Sitzman TJ
Cleft Palate Craniofac J 2018 May;55(5):639-648. Epub 2018 Feb 20 doi: 10.1177/1055665618757367. PMID: 29461877Free PMC Article
A retrospective evaluation of the aesthetics of the nasolabial complex after unilateral cleft lip repair using the Tennison-Randall technique: a study of 44 cases treated in a single cleft center.
Iliopoulos C, Mitsimponas K, Lazaridou D, Neukam FW, Stelzle F
J Craniomaxillofac Surg 2014 Dec;42(8):1679-83. Epub 2014 May 24 doi: 10.1016/j.jcms.2014.05.013. PMID: 24962045

Clinical prediction guides

The Validation of an Innovative Method for 3D Capture and Analysis of the Nasolabial Region in Cleft Cases.
Ayoub A, Khan A, Aldhanhani A, Alnaser H, Naudi K, Ju X, Gillgrass T, Mossey P
Cleft Palate Craniofac J 2021 Jan;58(1):98-104. Epub 2020 Aug 12 doi: 10.1177/1055665620946987. PMID: 32783457Free PMC Article
Evaluation of nasolabial aesthetics by different groups in operated unilateral cleft lip and palate.
Dogan E, Tiftikcioglu Y, Dogan S
J Stomatol Oral Maxillofac Surg 2020 Dec;121(6):672-679. Epub 2020 Jan 30 doi: 10.1016/j.jormas.2020.01.005. PMID: 32007634
Assessment of regional asymmetry of the face before and after surgical correction of unilateral cleft lip.
Al-Rudainy D, Ju X, Stanton S, Mehendale FV, Ayoub A
J Craniomaxillofac Surg 2018 Jun;46(6):974-978. Epub 2018 Apr 6 doi: 10.1016/j.jcms.2018.03.023. PMID: 29752048
Methods of assessment of cleft-related facial deformity: a review.
Al-Omari I, Millett DT, Ayoub AF
Cleft Palate Craniofac J 2005 Mar;42(2):145-56. doi: 10.1597/02-149.1. PMID: 15748105
Suction-assisted lipectomy for lipodystrophy syndromes attributed to HIV-protease inhibitor use.
Wolfort FG, Cetrulo CL Jr, Nevarre DR
Plast Reconstr Surg 1999 Nov;104(6):1814-20; discussion 1821-2. PMID: 10541186

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