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Abnormal nasolabial region morphology

MedGen UID:
870766
•Concept ID:
C4025223
•
Anatomical Abnormality
Synonyms: Abnormality of the nasolabial region; Anomaly of the nasolabial region; Deformity of the nasolabial region; Malformation of the nasolabial region
 
HPO: HP:0005289

Term Hierarchy

CClinical test,  RResearch test,  OOMIM,  GGeneReviews,  VClinVar  
  • CROGVAbnormal nasolabial region morphology

Professional guidelines

PubMed

Single-Stage Posterior Vomerine Ostectomy and Primary Cheiloplasty in Patients with Bilateral Cleft Lip & Palate and Protuberant Premaxilla.
Hamdan US, Younan RA, Haddad M, Melhem AM, Najjar W, Hussein S, Kantar RS, Annan B, Johnson A, Liau J
Cleft Palate Craniofac J 2024 Oct;61(10):1670-1678. Epub 2023 May 30 doi: 10.1177/10556656231179609. PMID: 37253459
Nasal malformations associated with unilateral cleft lip. Accurate diagnosis and management.
Talmant JC
Scand J Plast Reconstr Surg Hand Surg 1993 Sep;27(3):183-91. doi: 10.3109/02844319309078110. PMID: 8272769

Recent clinical studies

Etiology

Is the Nasolabial Region Symmetric in Individuals With Cleft Lip and Palate?
Dindaroglu F, Dogan E, Dogan S
Cleft Palate Craniofac J 2024 Jan;61(1):12-19. Epub 2022 Aug 1 doi: 10.1177/10556656221116535. PMID: 35912442
Submental intubation in orthognathic surgery: initial experience.
Chandu A, Witherow H, Stewart A
Br J Oral Maxillofac Surg 2008 Oct;46(7):561-3. Epub 2008 Jun 27 doi: 10.1016/j.bjoms.2008.02.021. PMID: 18584927
A peculiar malformation of the upper lip: report of six cases.
Tange I
Cleft Palate Craniofac J 1997 Jan;34(1):73-8. doi: 10.1597/1545-1569_1997_034_0073_apmotu_2.3.co_2. PMID: 9003916
A six-center international study of treatment outcome in patients with clefts of the lip and palate: Part 4. Assessment of nasolabial appearance.
Asher-McDade C, Brattström V, Dahl E, McWilliam J, Mølsted K, Plint DA, Prahl-Andersen B, Semb G, Shaw WC, The RP
Cleft Palate Craniofac J 1992 Sep;29(5):409-12. doi: 10.1597/1545-1569_1992_029_0409_asciso_2.3.co_2. PMID: 1472518
Management of maxillary hypoplasia by Le Fort I osteotomy of the maxilla.
Bromige MR
Ann Acad Med Singap 1988 Jul;17(3):407-14. PMID: 3064703

Diagnosis

Identification of a novel pathogenic mutation of the MYH3 gene in a family with distal arthrogryposis type 2B.
Wang WB, Kong LC, Zuo RT, Kang QL
Mol Med Rep 2020 Jan;21(1):438-444. Epub 2019 Nov 15 doi: 10.3892/mmr.2019.10820. PMID: 31746383
Three-dimensional assessment of facial asymmetry in preschool patients with orofacial clefts after neonatal cheiloplasty.
Moslerová V, Dadáková M, Dupej J, Hoffmannova E, Borský J, Černý M, Bejda P, Kočandrlová K, Velemínská J
Int J Pediatr Otorhinolaryngol 2018 May;108:40-45. Epub 2018 Feb 16 doi: 10.1016/j.ijporl.2018.02.023. PMID: 29605363
Nasal changes after orthognathic surgery for patients with prognathism and Class III malocclusion: analysis using three-dimensional photogrammetry.
Worasakwutiphong S, Chuang YF, Chang HW, Lin HH, Lin PJ, Lo LJ
J Formos Med Assoc 2015 Feb;114(2):112-23. Epub 2014 Dec 20 doi: 10.1016/j.jfma.2014.10.003. PMID: 25534453
Clinical presentation and differential diagnosis of nasolabial cyst.
Nixdorf DR, Peters E, Lung KE
J Can Dent Assoc 2003 Mar;69(3):146-9. PMID: 12622877
Anthropometry for syndromology.
Lakshminarayana P, Janardhan K, David HS
Indian J Pediatr 1991 Mar-Apr;58(2):253-8. doi: 10.1007/BF02751131. PMID: 1879907

Therapy

Three-dimensional assessment of facial asymmetry in preschool patients with orofacial clefts after neonatal cheiloplasty.
Moslerová V, Dadáková M, Dupej J, Hoffmannova E, Borský J, Černý M, Bejda P, Kočandrlová K, Velemínská J
Int J Pediatr Otorhinolaryngol 2018 May;108:40-45. Epub 2018 Feb 16 doi: 10.1016/j.ijporl.2018.02.023. PMID: 29605363
Judgment of Nasolabial Esthetics in Cleft Lip and Palate Is Not Influenced by Overall Facial Attractiveness.
Kocher K, Kowalski P, Kolokitha OE, Katsaros C, Fudalej PS
Cleft Palate Craniofac J 2016 May;53(3):e45-52. Epub 2015 May 1 doi: 10.1597/14-019. PMID: 25932752
Nasal changes after orthognathic surgery for patients with prognathism and Class III malocclusion: analysis using three-dimensional photogrammetry.
Worasakwutiphong S, Chuang YF, Chang HW, Lin HH, Lin PJ, Lo LJ
J Formos Med Assoc 2015 Feb;114(2):112-23. Epub 2014 Dec 20 doi: 10.1016/j.jfma.2014.10.003. PMID: 25534453
Aesthetic evaluation of the nasolabial region in children with unilateral cleft lip and palate comparing expert versus nonexperience health professionals.
Paiva TS, Andre M, Paiva WS, Mattos BS
Biomed Res Int 2014;2014:460106. Epub 2014 Jul 13 doi: 10.1155/2014/460106. PMID: 25126560Free PMC Article
Nasolabial aesthetics.
Mitchell C, Oeltjen J, Panthaki Z, Thaller SR
J Craniofac Surg 2007 Jul;18(4):756-65. doi: 10.1097/scs.0b013e3180684360. PMID: 17667661

Prognosis

Dynamic Nasolabial Growth After Primary Surgery for Patients With Bilateral Cleft Lip: A Five-Year Follow-Up Study.
Wei Y, Zhong T, Yin X, Shi B, Zheng Q, Li J
J Oral Maxillofac Surg 2019 Oct;77(10):2125.e1-2125.e10. Epub 2019 May 30 doi: 10.1016/j.joms.2019.05.013. PMID: 31238020
The Eurocleft study: intercenter study of treatment outcome in patients with complete cleft lip and palate. Part 2: craniofacial form and nasolabial appearance.
Brattström V, Mølsted K, Prahl-Andersen B, Semb G, Shaw WC
Cleft Palate Craniofac J 2005 Jan;42(1):69-77. doi: 10.1597/02-119.2.1. PMID: 15643918
Clinical presentation and differential diagnosis of nasolabial cyst.
Nixdorf DR, Peters E, Lung KE
J Can Dent Assoc 2003 Mar;69(3):146-9. PMID: 12622877
A peculiar malformation of the upper lip: report of six cases.
Tange I
Cleft Palate Craniofac J 1997 Jan;34(1):73-8. doi: 10.1597/1545-1569_1997_034_0073_apmotu_2.3.co_2. PMID: 9003916
Management of maxillary hypoplasia by Le Fort I osteotomy of the maxilla.
Bromige MR
Ann Acad Med Singap 1988 Jul;17(3):407-14. PMID: 3064703

Clinical prediction guides

The Validation of an Innovative Method for 3D Capture and Analysis of the Nasolabial Region in Cleft Cases.
Ayoub A, Khan A, Aldhanhani A, Alnaser H, Naudi K, Ju X, Gillgrass T, Mossey P
Cleft Palate Craniofac J 2021 Jan;58(1):98-104. Epub 2020 Aug 12 doi: 10.1177/1055665620946987. PMID: 32783457Free PMC Article
Judgment of Nasolabial Esthetics in Cleft Lip and Palate Is Not Influenced by Overall Facial Attractiveness.
Kocher K, Kowalski P, Kolokitha OE, Katsaros C, Fudalej PS
Cleft Palate Craniofac J 2016 May;53(3):e45-52. Epub 2015 May 1 doi: 10.1597/14-019. PMID: 25932752
Methods of assessment of cleft-related facial deformity: a review.
Al-Omari I, Millett DT, Ayoub AF
Cleft Palate Craniofac J 2005 Mar;42(2):145-56. doi: 10.1597/02-149.1. PMID: 15748105
A peculiar malformation of the upper lip: report of six cases.
Tange I
Cleft Palate Craniofac J 1997 Jan;34(1):73-8. doi: 10.1597/1545-1569_1997_034_0073_apmotu_2.3.co_2. PMID: 9003916
Use of standardized video recordings to assess cleft surgery outcome.
Morrant DG, Shaw WC
Cleft Palate Craniofac J 1996 Mar;33(2):134-42. doi: 10.1597/1545-1569_1996_033_0134_uosvrt_2.3.co_2. PMID: 8695621

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