U.S. flag

An official website of the United States government

Format

Send to:

Choose Destination

Abnormal cerebral ventricle morphology

MedGen UID:
871242
•Concept ID:
C4025724
•
Anatomical Abnormality
Synonym: Abnormality of the cerebral ventricles
 
HPO: HP:0002118

Definition

Any structural abnormality of the cerebral ventricles. [from HPO]

Professional guidelines

PubMed

Prenatal diagnosis and outcome of fetuses with isolated agenesis of septum pellucidum: cohort study and meta-analysis.
Di Pasquo E, Kuleva M, Arthuis C, Morganelli G, Ormitti F, Millischer AE, Grevent D, Ville Y, Ghi T, Salomon LJ
Ultrasound Obstet Gynecol 2022 Feb;59(2):153-161. Epub 2022 Jan 18 doi: 10.1002/uog.23759. PMID: 34396620
Society for Maternal-Fetal Medicine Consult Series #57: Evaluation and management of isolated soft ultrasound markers for aneuploidy in the second trimester: (Replaces Consults #10, Single umbilical artery, October 2010; #16, Isolated echogenic bowel diagnosed on second-trimester ultrasound, August 2011; #17, Evaluation and management of isolated renal pelviectasis on second-trimester ultrasound, December 2011; #25, Isolated fetal choroid plexus cysts, April 2013; #27, Isolated echogenic intracardiac focus, August 2013).
Society for Maternal-Fetal Medicine (SMFM). Electronic address: pubs@smfm.org, Prabhu M, Kuller JA, Biggio JR
Am J Obstet Gynecol 2021 Oct;225(4):B2-B15. Epub 2021 Jun 23 doi: 10.1016/j.ajog.2021.06.079. PMID: 34171388
Agenesis of the septum pellucidum: Prenatal diagnosis and outcome.
Borkowski-Tillman T, Garcia-Rodriguez R, Viñals F, Branco M, Kradjen-Haratz K, Ben-Sira L, Lerman-Sagie T, Malinger G
Prenat Diagn 2020 May;40(6):674-680. Epub 2020 Mar 31 doi: 10.1002/pd.5663. PMID: 32037567

Recent clinical studies

Etiology

Fetal cerebral ventriculomegaly: What do we tell the prospective parents?
Giorgione V, Haratz KK, Constantini S, Birnbaum R, Malinger G
Prenat Diagn 2022 Dec;42(13):1674-1681. Epub 2022 Nov 21 doi: 10.1002/pd.6266. PMID: 36371614Free PMC Article
Cerebrospinal fluid and the early brain development of autism.
Shen MD
J Neurodev Disord 2018 Dec 13;10(1):39. doi: 10.1186/s11689-018-9256-7. PMID: 30541429Free PMC Article
The Ventricular System of the Brain: Anatomy and Normal Variations.
Stratchko L, Filatova I, Agarwal A, Kanekar S
Semin Ultrasound CT MR 2016 Apr;37(2):72-83. Epub 2016 Jan 29 doi: 10.1053/j.sult.2016.01.004. PMID: 27063657
Towards the understanding of Down syndrome using mouse models.
Yamakawa K
Congenit Anom (Kyoto) 2012 Jun;52(2):67-71. doi: 10.1111/j.1741-4520.2012.00367.x. PMID: 22639990
MR signal abnormalities at 1.5 T in Alzheimer's dementia and normal aging.
Fazekas F, Chawluk JB, Alavi A, Hurtig HI, Zimmerman RA
AJR Am J Roentgenol 1987 Aug;149(2):351-6. doi: 10.2214/ajr.149.2.351. PMID: 3496763

Diagnosis

Machine learning in prenatal MRI predicts postnatal ventricular abnormalities in fetuses with isolated ventriculomegaly.
Chen X, Xu D, Gu X, Li Z, Zhang Y, Wu P, Huang Z, Zhang J, Li Y
Eur Radiol 2024 Nov;34(11):7115-7124. Epub 2024 May 10 doi: 10.1007/s00330-024-10785-6. PMID: 38730032
Fetal cerebral ventriculomegaly: What do we tell the prospective parents?
Giorgione V, Haratz KK, Constantini S, Birnbaum R, Malinger G
Prenat Diagn 2022 Dec;42(13):1674-1681. Epub 2022 Nov 21 doi: 10.1002/pd.6266. PMID: 36371614Free PMC Article
The Ventricular System of the Brain: Anatomy and Normal Variations.
Stratchko L, Filatova I, Agarwal A, Kanekar S
Semin Ultrasound CT MR 2016 Apr;37(2):72-83. Epub 2016 Jan 29 doi: 10.1053/j.sult.2016.01.004. PMID: 27063657
Colpocephaly in adults.
Esenwa CC, Leaf DE
BMJ Case Rep 2013 May 22;2013 doi: 10.1136/bcr-2013-009505. PMID: 23704444Free PMC Article
Interhemispheric and quadrigeminal cysts.
Spennato P, Ruggiero C, Aliberti F, Buonocore MC, Trischitta V, Cinalli G
World Neurosurg 2013 Feb;79(2 Suppl):S20.e1-7. Epub 2012 Feb 10 doi: 10.1016/j.wneu.2012.02.010. PMID: 22381822

Therapy

Choroid plexus and perivascular space enlargement in neuropsychiatric systemic lupus erythematosus.
Gueye M, Preziosa P, Ramirez GA, Bozzolo EP, Canti V, Margoni M, Meani A, Moiola L, Rovere-Querini P, Manfredi AA, Filippi M, Rocca MA
Mol Psychiatry 2024 Feb;29(2):359-368. Epub 2023 Nov 30 doi: 10.1038/s41380-023-02332-4. PMID: 38036603
Vascular Behçet's syndrome: an update.
Emmi G, Bettiol A, Silvestri E, Di Scala G, Becatti M, Fiorillo C, Prisco D
Intern Emerg Med 2019 Aug;14(5):645-652. Epub 2018 Nov 29 doi: 10.1007/s11739-018-1991-y. PMID: 30499073
Intraventricular neuroendoscopy: complication avoidance and management.
Chowdhry SA, Cohen AR
World Neurosurg 2013 Feb;79(2 Suppl):S15.e1-10. Epub 2012 Feb 10 doi: 10.1016/j.wneu.2012.02.030. PMID: 22381833
Spontaneous intracranial hypotension.
Mokri B
Curr Neurol Neurosci Rep 2001 Mar;1(2):109-17. doi: 10.1007/s11910-001-0005-y. PMID: 11898506
Spontaneous intracranial hypotension.
Mokri B
Curr Pain Headache Rep 2001 Jun;5(3):284-91. doi: 10.1007/s11916-001-0045-7. PMID: 11309218

Prognosis

Machine learning in prenatal MRI predicts postnatal ventricular abnormalities in fetuses with isolated ventriculomegaly.
Chen X, Xu D, Gu X, Li Z, Zhang Y, Wu P, Huang Z, Zhang J, Li Y
Eur Radiol 2024 Nov;34(11):7115-7124. Epub 2024 May 10 doi: 10.1007/s00330-024-10785-6. PMID: 38730032
Fetal cerebral ventriculomegaly: What do we tell the prospective parents?
Giorgione V, Haratz KK, Constantini S, Birnbaum R, Malinger G
Prenat Diagn 2022 Dec;42(13):1674-1681. Epub 2022 Nov 21 doi: 10.1002/pd.6266. PMID: 36371614Free PMC Article
Dandy-Walker Malformation.
Society for Maternal-Fetal Medicine (SMFM), Monteagudo A
Am J Obstet Gynecol 2020 Dec;223(6):B38-B41. Epub 2020 Nov 7 doi: 10.1016/j.ajog.2020.08.184. PMID: 33168220
Endoscopic aqueductoplasty and stenting.
Fritsch MJ, Schroeder HW
World Neurosurg 2013 Feb;79(2 Suppl):S20.e15-8. Epub 2012 Feb 10 doi: 10.1016/j.wneu.2012.02.013. PMID: 22381819
Neurocutaneous melanosis.
Di Rocco F, Sabatino G, Koutzoglou M, Battaglia D, Caldarelli M, Tamburrini G
Childs Nerv Syst 2004 Jan;20(1):23-8. Epub 2003 Oct 24 doi: 10.1007/s00381-003-0835-9. PMID: 14576958

Clinical prediction guides

Fetal cerebral ventriculomegaly: What do we tell the prospective parents?
Giorgione V, Haratz KK, Constantini S, Birnbaum R, Malinger G
Prenat Diagn 2022 Dec;42(13):1674-1681. Epub 2022 Nov 21 doi: 10.1002/pd.6266. PMID: 36371614Free PMC Article
Periventricular magnetisation transfer abnormalities in early multiple sclerosis.
Pirpamer L, Kincses B, Kincses ZT, Kiss C, Damulina A, Khalil M, Stollberger R, Schmidt R, Enzinger C, Ropele S
Neuroimage Clin 2022;34:103012. Epub 2022 Apr 20 doi: 10.1016/j.nicl.2022.103012. PMID: 35487133Free PMC Article
Development of brain ventricular system.
Korzh V
Cell Mol Life Sci 2018 Feb;75(3):375-383. Epub 2017 Aug 5 doi: 10.1007/s00018-017-2605-y. PMID: 28780589Free PMC Article
Management of colloid cyst of third ventricle.
Yadav YR, Yadav N, Parihar V, Kher Y, Ratre S
Turk Neurosurg 2015;25(3):362-71. doi: 10.5137/1019-5149.JTN.11086-14.1. PMID: 26037175
MR signal abnormalities at 1.5 T in Alzheimer's dementia and normal aging.
Fazekas F, Chawluk JB, Alavi A, Hurtig HI, Zimmerman RA
AJR Am J Roentgenol 1987 Aug;149(2):351-6. doi: 10.2214/ajr.149.2.351. PMID: 3496763

Recent systematic reviews

An eye on the future for defeating hydrocephalus, ciliary dyskinesia-related hydrocephalus: review article.
Hasanain AA, Soliman MAR, Elwy R, Ezzat AAM, Abdel-Bari SH, Marx S, Jenkins A, El Refaee E, Zohdi A
Br J Neurosurg 2022 Jun;36(3):329-339. Epub 2022 May 17 doi: 10.1080/02688697.2022.2074373. PMID: 35579079
Familial colloid cysts: not a chance occurrence.
Giantini-Larsen AM, Garton ALA, Villamater FN, Kuzan-Fischer CM, Savage NJ, Cunniff CM, Ross ME, Christos PJ, Stieg PE, Souweidane MM
J Neurooncol 2022 Apr;157(2):321-332. Epub 2022 Mar 3 doi: 10.1007/s11060-022-03966-0. PMID: 35243591
Outcome of fetuses with prenatal diagnosis of isolated severe bilateral ventriculomegaly: systematic review and meta-analysis.
Carta S, Kaelin Agten A, Belcaro C, Bhide A
Ultrasound Obstet Gynecol 2018 Aug;52(2):165-173. doi: 10.1002/uog.19038. PMID: 29484752
Neurodevelopmental outcome in isolated mild fetal ventriculomegaly: systematic review and meta-analysis.
Pagani G, Thilaganathan B, Prefumo F
Ultrasound Obstet Gynecol 2014 Sep;44(3):254-60. Epub 2014 Jul 21 doi: 10.1002/uog.13364. PMID: 24623452
Brainstem cavernous malformations.
Gross BA, Batjer HH, Awad IA, Bendok BR
Neurosurgery 2009 May;64(5):E805-18; discussion E818. doi: 10.1227/01.NEU.0000343668.44288.18. PMID: 19404127

Supplemental Content

Table of contents

    Clinical resources

    Practice guidelines

    • PubMed
      See practice and clinical guidelines in PubMed. The search results may include broader topics and may not capture all published guidelines. See the FAQ for details.
    • Bookshelf
      See practice and clinical guidelines in NCBI Bookshelf. The search results may include broader topics and may not capture all published guidelines. See the FAQ for details.

    Consumer resources

    Reviews

    Related information

    • PMC Articles
      Related information in PubMed Central Links
    • PubMed
      Related literature resources in PubMed

    Recent activity

    Clear Turn Off Turn On

    Your browsing activity is empty.

    Activity recording is turned off.

    Turn recording back on

    See more...