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Fibroepithelial polyp of the anus

MedGen UID:
87519
•Concept ID:
C0345903
•
Anatomical Abnormality
Synonyms: Anal Fibroepithelial Polyp; anal fibroepithelial polyp; Anal Fibrous Polyp; anal fibrous polyp; Anal skin tag; Anal Tag; Anal tag; anal tag; anus skin tag; Fibroepithelial Polyp of Anus; fibroepithelial polyp of anus; Fibroepithelial Polyp of the Anus; fibroepithelial polyp of the anus; Fibrous polyp of anus; Fibrous Polyp of Anus; fibrous polyp of anus; Fibrous Polyp of the Anus; fibrous polyp of the anus; skin tag of anus
SNOMED CT: Anal skin tag (195469007); Anal tag (195469007); Fibrous polyp of anus (195469007)
 
Monarch Initiative: MONDO:0006549

Definition

A non-neoplastic polypoid lesion that arises from the anal canal or perianal skin. It is composed of dense fibrous stroma and it is covered by squamous epithelium. [from NCI]

Term Hierarchy

CClinical test,  RResearch test,  OOMIM,  GGeneReviews,  VClinVar  
  • CROGVFibroepithelial polyp of the anus

Recent clinical studies

Etiology

Giant Anal Fibroepithelial Polyp in a Healthy Teenage Boy: A Case Report and Literature Review.
Park K, Abbas P, Langenburg S, Poulik J, Hanan A, Shehata BM
Fetal Pediatr Pathol 2022 Jun;41(3):493-498. Epub 2020 Nov 9 doi: 10.1080/15513815.2020.1843575. PMID: 33164595
Benign anal and perianal polypoid neoplasms and tumor-like lesions.
AbdullGaffar B, Keloth T, Al-Hattawi M, Al Marzouqi M, ElTayeb Y
Pathol Res Pract 2012 Dec 15;208(12):719-25. Epub 2012 Oct 22 doi: 10.1016/j.prp.2012.09.004. PMID: 23089289
P16/CDKN2A and Ki-67 enhance the detection of anal intraepithelial neoplasia and condyloma and correlate with human papillomavirus detection by polymerase chain reaction.
Pirog EC, Quint KD, Yantiss RK
Am J Surg Pathol 2010 Oct;34(10):1449-55. doi: 10.1097/PAS.0b013e3181f0f52a. PMID: 20871219
Verrucous carcinoma masquerading as a giant fibroepithelial polyp.
Mercer SE, Khalil D, Emanuel PO, Goldenberg G
Int J Surg Pathol 2010 Oct;18(5):347-51. Epub 2010 Jul 28 doi: 10.1177/1066896910377786. PMID: 20667928
HPV prevalence in anal warts tested with the MY09/MY11 SHARP Signal system.
Strand A, Andersson S, Zehbe I, Wilander E
Acta Derm Venereol 1999 May;79(3):226-9. doi: 10.1080/000155599750011048. PMID: 10384924

Diagnosis

Giant Anal Fibroepithelial Polyp in a Healthy Teenage Boy: A Case Report and Literature Review.
Park K, Abbas P, Langenburg S, Poulik J, Hanan A, Shehata BM
Fetal Pediatr Pathol 2022 Jun;41(3):493-498. Epub 2020 Nov 9 doi: 10.1080/15513815.2020.1843575. PMID: 33164595
Anal Fibroepithelial Polyp With Epithelial Vascular Pseudoinvasion.
Fellegara G, Di Mari N
Int J Surg Pathol 2020 Oct;28(7):764-767. Epub 2020 May 21 doi: 10.1177/1066896920925919. PMID: 32434434
P16/CDKN2A and Ki-67 enhance the detection of anal intraepithelial neoplasia and condyloma and correlate with human papillomavirus detection by polymerase chain reaction.
Pirog EC, Quint KD, Yantiss RK
Am J Surg Pathol 2010 Oct;34(10):1449-55. doi: 10.1097/PAS.0b013e3181f0f52a. PMID: 20871219
Verrucous carcinoma masquerading as a giant fibroepithelial polyp.
Mercer SE, Khalil D, Emanuel PO, Goldenberg G
Int J Surg Pathol 2010 Oct;18(5):347-51. Epub 2010 Jul 28 doi: 10.1177/1066896910377786. PMID: 20667928
Obstructive ileus due to a giant fibroepithelial polyp of the anus.
Galanis I, Dragoumis D, Tsolakis M, Zarampoukas K, Zarampoukas T, Atmatzidis K
World J Gastroenterol 2009 Aug 7;15(29):3687-90. doi: 10.3748/wjg.15.3687. PMID: 19653351Free PMC Article

Therapy

HPV prevalence in anal warts tested with the MY09/MY11 SHARP Signal system.
Strand A, Andersson S, Zehbe I, Wilander E
Acta Derm Venereol 1999 May;79(3):226-9. doi: 10.1080/000155599750011048. PMID: 10384924

Prognosis

P16/CDKN2A and Ki-67 enhance the detection of anal intraepithelial neoplasia and condyloma and correlate with human papillomavirus detection by polymerase chain reaction.
Pirog EC, Quint KD, Yantiss RK
Am J Surg Pathol 2010 Oct;34(10):1449-55. doi: 10.1097/PAS.0b013e3181f0f52a. PMID: 20871219

Clinical prediction guides

P16/CDKN2A and Ki-67 enhance the detection of anal intraepithelial neoplasia and condyloma and correlate with human papillomavirus detection by polymerase chain reaction.
Pirog EC, Quint KD, Yantiss RK
Am J Surg Pathol 2010 Oct;34(10):1449-55. doi: 10.1097/PAS.0b013e3181f0f52a. PMID: 20871219

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