U.S. flag

An official website of the United States government

Format

Send to:

Choose Destination

Focal Segmental Glomerulosclerosis Tip Lesion Variant

MedGen UID:
885369
Concept ID:
C4054943
Disease or Syndrome

Definition

A variant of FSGS characterized by scarring of the glomerulus adjacent to the origin of the proximal convoluted tubule; this occurs in the absence of collapsing and perihilar FSGS. (D''Agati VD, et al. ""Pathologic Classification of Focal Segmental Glomerulosclerosis: A Working Proposal."" Am J Kidney Dis 43.2 (2004): 368-82.) [from NCI]

Term Hierarchy

CClinical test,  RResearch test,  OOMIM,  GGeneReviews,  VClinVar  
  • CROGVFocal Segmental Glomerulosclerosis Tip Lesion Variant

Professional guidelines

PubMed

Laurin LP, Gasim AM, Poulton CJ, Hogan SL, Jennette JC, Falk RJ, Foster BJ, Nachman PH
Clin J Am Soc Nephrol 2016 Mar 7;11(3):386-94. Epub 2016 Feb 16 doi: 10.2215/CJN.07110615. PMID: 26912551Free PMC Article
Meehan SM, Kim L, Chang A
Virchows Arch 2012 Apr;460(4):429-35. Epub 2012 Mar 3 doi: 10.1007/s00428-012-1213-3. PMID: 22388441

Recent clinical studies

Etiology

Peng Y, Gao C, Xu C, Wu H, Wang M, Wang R, Wei Y, Li X, Ju T, Xia Z, Zhang P
J Nephrol 2023 Jul;36(6):1581-1590. Epub 2023 Apr 7 doi: 10.1007/s40620-023-01631-x. PMID: 37027095
Wang H, Wan C, Jiang M, Zhang C
Curr Med Sci 2022 Oct;42(5):1007-1014. Epub 2022 Sep 30 doi: 10.1007/s11596-022-2628-y. PMID: 36178577
Mungan S, Turkmen E, Aydin MC, Saglam AE, Baydar DE
Ren Fail 2015 Jun;37(5):858-65. Epub 2015 Apr 10 doi: 10.3109/0886022X.2015.1033635. PMID: 25857429
Stokes MB, D'Agati VD
Adv Chronic Kidney Dis 2014 Sep;21(5):400-7. doi: 10.1053/j.ackd.2014.02.010. PMID: 25168828
Arias LF, Franco-Alzate C, Rojas SL
Nephrol Dial Transplant 2011 Jul;26(7):2215-21. Epub 2010 Nov 10 doi: 10.1093/ndt/gfq668. PMID: 21068139

Diagnosis

Wang H, Wan C, Jiang M, Zhang C
Curr Med Sci 2022 Oct;42(5):1007-1014. Epub 2022 Sep 30 doi: 10.1007/s11596-022-2628-y. PMID: 36178577
Han MH, Kim YJ
Biomed Res Int 2016;2016:9375753. Epub 2016 May 9 doi: 10.1155/2016/9375753. PMID: 27247945Free PMC Article
Mungan S, Turkmen E, Aydin MC, Saglam AE, Baydar DE
Ren Fail 2015 Jun;37(5):858-65. Epub 2015 Apr 10 doi: 10.3109/0886022X.2015.1033635. PMID: 25857429
Howie AJ
Pediatr Nephrol 2011 Aug;26(8):1197-205. Epub 2010 Dec 2 doi: 10.1007/s00467-010-1701-0. PMID: 21125407
Arias LF, Franco-Alzate C, Rojas SL
Nephrol Dial Transplant 2011 Jul;26(7):2215-21. Epub 2010 Nov 10 doi: 10.1093/ndt/gfq668. PMID: 21068139

Therapy

Sedlacek M, Pettus JR
CEN Case Rep 2022 May;11(2):225-230. Epub 2021 Nov 5 doi: 10.1007/s13730-021-00658-y. PMID: 34741283Free PMC Article
Mungan S, Turkmen E, Aydin MC, Saglam AE, Baydar DE
Ren Fail 2015 Jun;37(5):858-65. Epub 2015 Apr 10 doi: 10.3109/0886022X.2015.1033635. PMID: 25857429
Swarnalatha G, Ram R, Ismal KM, Vali S, Sahay M, Dakshinamurty KV
Saudi J Kidney Dis Transpl 2015 Jan;26(1):173-81. doi: 10.4103/1319-2442.148772. PMID: 25579744
Kwon YE, Han SH, Kie JH, An SY, Kim YL, Park KS, Nam KH, Leem AY, Oh HJ, Park JT, Chang TI, Kang EW, Kang SW, Choi KH, Lim BJ, Jeong HJ, Yoo TH
BMC Nephrol 2014 Mar 25;15:52. doi: 10.1186/1471-2369-15-52. PMID: 24666814Free PMC Article
Taneda S, Honda K, Uchida K, Nitta K, Yumura W, Oda H, Nagata M
Int Urol Nephrol 2012 Feb;44(1):183-96. Epub 2011 Mar 19 doi: 10.1007/s11255-011-9932-y. PMID: 21424374Free PMC Article

Prognosis

Wang H, Wan C, Jiang M, Zhang C
Curr Med Sci 2022 Oct;42(5):1007-1014. Epub 2022 Sep 30 doi: 10.1007/s11596-022-2628-y. PMID: 36178577
Han MH, Kim YJ
Biomed Res Int 2016;2016:9375753. Epub 2016 May 9 doi: 10.1155/2016/9375753. PMID: 27247945Free PMC Article
Mungan S, Turkmen E, Aydin MC, Saglam AE, Baydar DE
Ren Fail 2015 Jun;37(5):858-65. Epub 2015 Apr 10 doi: 10.3109/0886022X.2015.1033635. PMID: 25857429
Stokes MB, D'Agati VD
Adv Chronic Kidney Dis 2014 Sep;21(5):400-7. doi: 10.1053/j.ackd.2014.02.010. PMID: 25168828
Arias LF, Franco-Alzate C, Rojas SL
Nephrol Dial Transplant 2011 Jul;26(7):2215-21. Epub 2010 Nov 10 doi: 10.1093/ndt/gfq668. PMID: 21068139

Clinical prediction guides

Peng Y, Gao C, Xu C, Wu H, Wang M, Wang R, Wei Y, Li X, Ju T, Xia Z, Zhang P
J Nephrol 2023 Jul;36(6):1581-1590. Epub 2023 Apr 7 doi: 10.1007/s40620-023-01631-x. PMID: 37027095
Wang H, Wan C, Jiang M, Zhang C
Curr Med Sci 2022 Oct;42(5):1007-1014. Epub 2022 Sep 30 doi: 10.1007/s11596-022-2628-y. PMID: 36178577
Mungan S, Turkmen E, Aydin MC, Saglam AE, Baydar DE
Ren Fail 2015 Jun;37(5):858-65. Epub 2015 Apr 10 doi: 10.3109/0886022X.2015.1033635. PMID: 25857429
Swarnalatha G, Ram R, Ismal KM, Vali S, Sahay M, Dakshinamurty KV
Saudi J Kidney Dis Transpl 2015 Jan;26(1):173-81. doi: 10.4103/1319-2442.148772. PMID: 25579744
Tang X, Xu F, Chen DM, Zeng CH, Liu ZH
Clin Nephrol 2013 Aug;80(2):130-9. doi: 10.5414/CN107607. PMID: 23380386

Supplemental Content

Table of contents

    Practice guidelines

    • PubMed
      See practice and clinical guidelines in PubMed. The search results may include broader topics and may not capture all published guidelines. See the FAQ for details.
    • Bookshelf
      See practice and clinical guidelines in NCBI Bookshelf. The search results may include broader topics and may not capture all published guidelines. See the FAQ for details.

    Recent activity

    Your browsing activity is empty.

    Activity recording is turned off.

    Turn recording back on

    See more...