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Abnormal lactate dehydrogenase level

MedGen UID:
892640
•Concept ID:
C4073168
•
Finding
Synonym: Abnormal lactate dehydrogenase activity
 
HPO: HP:0045040

Definition

A deviation from the normal serum concentration/activity of lactate dehydrogenase (LDH), which catalyzes the reduction of pyruvate to form lactate. [from HPO]

Term Hierarchy

CClinical test,  RResearch test,  OOMIM,  GGeneReviews,  VClinVar  
  • Abnormal lactate dehydrogenase level

Professional guidelines

PubMed

Diagnosis and Management of Multiple Myeloma: A Review.
Cowan AJ, Green DJ, Kwok M, Lee S, Coffey DG, Holmberg LA, Tuazon S, Gopal AK, Libby EN
JAMA 2022 Feb 1;327(5):464-477. doi: 10.1001/jama.2022.0003. PMID: 35103762
Epidemiology, Staging, and Management of Multiple Myeloma.
Padala SA, Barsouk A, Barsouk A, Rawla P, Vakiti A, Kolhe R, Kota V, Ajebo GH
Med Sci (Basel) 2021 Jan 20;9(1) doi: 10.3390/medsci9010003. PMID: 33498356Free PMC Article
Hemolytic Anemia: Evaluation and Differential Diagnosis.
Phillips J, Henderson AC
Am Fam Physician 2018 Sep 15;98(6):354-361. PMID: 30215915

Recent clinical studies

Etiology

Clinicopathologic implications of tissue inhibitor of metalloproteinase-1-positive diffuse large B-cell lymphoma.
Choi JW, An JS, Lee JH, Lee ES, Kim KH, Kim YS
Mod Pathol 2006 Jul;19(7):963-73. Epub 2006 Apr 28 doi: 10.1038/modpathol.3800615. PMID: 16648868

Prognosis

Clinicopathologic implications of tissue inhibitor of metalloproteinase-1-positive diffuse large B-cell lymphoma.
Choi JW, An JS, Lee JH, Lee ES, Kim KH, Kim YS
Mod Pathol 2006 Jul;19(7):963-73. Epub 2006 Apr 28 doi: 10.1038/modpathol.3800615. PMID: 16648868

Clinical prediction guides

Clinicopathologic implications of tissue inhibitor of metalloproteinase-1-positive diffuse large B-cell lymphoma.
Choi JW, An JS, Lee JH, Lee ES, Kim KH, Kim YS
Mod Pathol 2006 Jul;19(7):963-73. Epub 2006 Apr 28 doi: 10.1038/modpathol.3800615. PMID: 16648868

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