U.S. flag

An official website of the United States government

Format

Send to:

Choose Destination

Bowel diverticulosis

MedGen UID:
892687
Concept ID:
C1395674
Disease or Syndrome
Synonym: Bowel diverticula
 
HPO: HP:0005222

Definition

The presence of multiple diverticula of the intestine. [from HPO]

Conditions with this feature

Ehlers-Danlos syndrome, classic type, 1
MedGen UID:
78660
Concept ID:
C0268335
Disease or Syndrome
Classic Ehlers-Danlos syndrome (cEDS) is a connective tissue disorder characterized by skin hyperextensibility, atrophic scarring, and generalized joint hypermobility (GJH). The skin is soft and doughy to the touch, and hyperextensible, extending easily and snapping back after release (unlike lax, redundant skin, as in cutis laxa). The skin is fragile, as manifested by splitting of the dermis following relatively minor trauma, especially over pressure points (knees, elbows) and areas prone to trauma (shins, forehead, chin). Wound healing is poor, and stretching of scars after apparently successful primary wound healing is characteristic. Complications of joint hypermobility, such as dislocations of the shoulder, patella, digits, hip, radius, and clavicle, usually resolve spontaneously or are easily managed by the affected individual. Other features include hypotonia with delayed motor development, fatigue and muscle cramps, and easy bruising. Mitral valve prolapse can occur infrequently, but tends to be of little clinical consequence. Aortic root dilatation has been reported, appears to be more common in young individuals, and rarely progresses.

Professional guidelines

PubMed

Rangan V, Lamont JT
Curr Gastroenterol Rep 2020 Jan 15;22(1):4. doi: 10.1007/s11894-019-0741-2. PMID: 31940112
Harbi H, Kardoun N, Fendri S, Dammak N, Toumi N, Guirat A, Mzali R
Presse Med 2017 Dec;46(12 Pt 1):1139-1143. Epub 2017 Nov 11 doi: 10.1016/j.lpm.2017.08.009. PMID: 29133083

Recent clinical studies

Etiology

Horesh N, Klang E, Gravetz A, Nevo Y, Amiel I, Amitai MM, Rosin D, Gutman M, Zmora O
J Laparoendosc Adv Surg Tech A 2016 Aug;26(8):596-9. Epub 2016 May 16 doi: 10.1089/lap.2016.0066. PMID: 27182822
Mansoori B, Delaney CP, Willis JE, Paspulati RM, Ros PR, Schmid-Tannwald C, Herrmann KA
Eur Radiol 2016 Sep;26(9):2881-91. Epub 2015 Nov 23 doi: 10.1007/s00330-015-4098-0. PMID: 26597545
Cunningham SC, Gannon CJ, Napolitano LM
Am J Surg 2005 Jul;190(1):37-8. doi: 10.1016/j.amjsurg.2005.03.024. PMID: 15972168
Akhrass R, Yaffe MB, Fischer C, Ponsky J, Shuck JM
J Am Coll Surg 1997 Apr;184(4):383-8. PMID: 9100684
Montgomery RD, Haboubi NY, Mike NH, Chesner IM, Asquith P
Age Ageing 1986 Jul;15(4):235-40. doi: 10.1093/ageing/15.4.235. PMID: 3092595

Diagnosis

Lamb R, Kahlon A, Sukumar S, Layton B
Clin Radiol 2022 Apr;77(4):264-273. Epub 2022 Jan 7 doi: 10.1016/j.crad.2021.12.003. PMID: 35012738
Rangan V, Lamont JT
Curr Gastroenterol Rep 2020 Jan 15;22(1):4. doi: 10.1007/s11894-019-0741-2. PMID: 31940112
Harbi H, Kardoun N, Fendri S, Dammak N, Toumi N, Guirat A, Mzali R
Presse Med 2017 Dec;46(12 Pt 1):1139-1143. Epub 2017 Nov 11 doi: 10.1016/j.lpm.2017.08.009. PMID: 29133083
Transue DL, Hanna TN, Shekhani H, Rohatgi S, Khosa F, Johnson JO
Emerg Radiol 2017 Apr;24(2):195-205. Epub 2016 Nov 4 doi: 10.1007/s10140-016-1448-4. PMID: 27815648
Horesh N, Klang E, Gravetz A, Nevo Y, Amiel I, Amitai MM, Rosin D, Gutman M, Zmora O
J Laparoendosc Adv Surg Tech A 2016 Aug;26(8):596-9. Epub 2016 May 16 doi: 10.1089/lap.2016.0066. PMID: 27182822

Therapy

Jambulingam R, Nanayakkara G
BMJ Case Rep 2019 Jul 12;12(7) doi: 10.1136/bcr-2018-228811. PMID: 31302616Free PMC Article
Ladiwala ZFR, Sheikh R, Ahmed A, Zahid I, Memon AS
BMC Surg 2018 Aug 29;18(1):67. doi: 10.1186/s12893-018-0399-y. PMID: 30157820Free PMC Article
Corcelles R, Pavel M, Lacy A
JSLS 2014 Jan-Mar;18(1):142-5. doi: 10.4293/108680813X13654754535755. PMID: 24680159Free PMC Article
Giday SA, Pickett-Blakely OE, Buscaglia JM, Mullin GE
Gastrointest Endosc 2009 Feb;69(2):384-6. Epub 2008 Jun 18 doi: 10.1016/j.gie.2008.03.1085. PMID: 18565525
Malik A, Lukaszewski K, Caroline D, Parkman H, DeSipio J, Banson F, Bazir K, Reddy L, Srinivasan R, Fisher R, Miller L
Dig Dis Sci 2005 Apr;50(4):649-55. doi: 10.1007/s10620-005-2551-7. PMID: 15844696

Prognosis

Sotirova I, Gklavas A, Papalouka D, Gourtsoyianni S, Christodoulou D, Papaconstantinou I
Med Arch 2020 Apr;74(2):142-145. doi: 10.5455/medarh.2020.74.142-145. PMID: 32577058Free PMC Article
Harbi H, Kardoun N, Fendri S, Dammak N, Toumi N, Guirat A, Mzali R
Presse Med 2017 Dec;46(12 Pt 1):1139-1143. Epub 2017 Nov 11 doi: 10.1016/j.lpm.2017.08.009. PMID: 29133083
Horesh N, Klang E, Gravetz A, Nevo Y, Amiel I, Amitai MM, Rosin D, Gutman M, Zmora O
J Laparoendosc Adv Surg Tech A 2016 Aug;26(8):596-9. Epub 2016 May 16 doi: 10.1089/lap.2016.0066. PMID: 27182822
Cunningham SC, Gannon CJ, Napolitano LM
Am J Surg 2005 Jul;190(1):37-8. doi: 10.1016/j.amjsurg.2005.03.024. PMID: 15972168
Lempinen M, Salmela K, Kemppainen E
Scand J Gastroenterol 2004 Sep;39(9):905-9. doi: 10.1080/00365520410006288. PMID: 15513392

Clinical prediction guides

Ladiwala ZFR, Sheikh R, Ahmed A, Zahid I, Memon AS
BMC Surg 2018 Aug 29;18(1):67. doi: 10.1186/s12893-018-0399-y. PMID: 30157820Free PMC Article
Mansoori B, Delaney CP, Willis JE, Paspulati RM, Ros PR, Schmid-Tannwald C, Herrmann KA
Eur Radiol 2016 Sep;26(9):2881-91. Epub 2015 Nov 23 doi: 10.1007/s00330-015-4098-0. PMID: 26597545
Lempinen M, Salmela K, Kemppainen E
Scand J Gastroenterol 2004 Sep;39(9):905-9. doi: 10.1080/00365520410006288. PMID: 15513392
Beal SL, Walton CB, Bodai BI
Am J Gastroenterol 1987 Feb;82(2):162-4. PMID: 3101487

Supplemental Content

Table of contents

    Clinical resources

    Practice guidelines

    • PubMed
      See practice and clinical guidelines in PubMed. The search results may include broader topics and may not capture all published guidelines. See the FAQ for details.

    Consumer resources

    Recent activity

    Your browsing activity is empty.

    Activity recording is turned off.

    Turn recording back on

    See more...