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Abnormal retinal morphology on macular OCT

MedGen UID:
893077
•Concept ID:
C4073082
•
Finding
HPO: HP:0030612

Professional guidelines

PubMed

Intensive Glycemic Management Is Associated With Reduced Retinal Structure Abnormalities on Ocular Coherence Tomography in the DCCT/EDIC Study.
Blodi B, Gardner TW, Gao X, Sun JK, Lorenzi GM, Olmos de Koo LC, Das A, White NH, Gubitosi-Klug RA, Aiello LP, Bebu I; DCCT/EDIC Research Group
Diabetes Care 2024 Sep 1;47(9):1522-1529. doi: 10.2337/dc23-2408. PMID: 38551949Free PMC Article
Treatment Effects in Retinal Angiomatous Proliferation Imaged with OCT Angiography.
de Jong JH, Braaf B, Amarakoon S, Gräfe M, Yzer S, Vermeer KA, Missotten T, de Boer JF, van Velthoven MEJ
Ophthalmologica 2019;241(3):143-153. Epub 2018 Sep 18 doi: 10.1159/000491798. PMID: 30227415Free PMC Article
Current management strategy of polypoidal choroidal vasculopathy.
Ho CPS, Lai TYY
Indian J Ophthalmol 2018 Dec;66(12):1727-1735. doi: 10.4103/ijo.IJO_975_18. PMID: 30451173Free PMC Article

Recent clinical studies

Etiology

Foveal Hypoplasia in CRB1-Related Retinopathies.
Rodriguez-Martinez AC, Higgins BE, Tailor-Hamblin V, Malka S, Cheloni R, Collins AM, Bladen J, Henderson R, Moosajee M
Int J Mol Sci 2023 Sep 11;24(18) doi: 10.3390/ijms241813932. PMID: 37762234Free PMC Article
Multimodal imaging in pachychoroid spectrum.
Safi H, Ahmadieh H, Hassanpour K, Safi S
Surv Ophthalmol 2022 Mar-Apr;67(2):579-590. Epub 2021 Jul 29 doi: 10.1016/j.survophthal.2021.07.004. PMID: 34331955
Mitochondrial Retinopathy.
Birtel J, von Landenberg C, Gliem M, Gliem C, Reimann J, Kunz WS, Herrmann P, Betz C, Caswell R, Nesbitt V, Kornblum C, Charbel Issa P
Ophthalmol Retina 2022 Jan;6(1):65-79. Epub 2021 Jul 10 doi: 10.1016/j.oret.2021.02.017. PMID: 34257060
Retinal Manifestations of Idiopathic Intracranial Hypertension.
Nichani P, Micieli JA
Ophthalmol Retina 2021 May;5(5):429-437. Epub 2020 Aug 26 doi: 10.1016/j.oret.2020.08.016. PMID: 32860958
Multiple retinal anomalies in schizophrenia.
Adams SA, Nasrallah HA
Schizophr Res 2018 May;195:3-12. Epub 2017 Jul 27 doi: 10.1016/j.schres.2017.07.018. PMID: 28755877

Diagnosis

OCT angiography 2023 update: focus on diabetic retinopathy.
Crincoli E, Sacconi R, Querques L, Querques G
Acta Diabetol 2024 May;61(5):533-541. Epub 2024 Feb 20 doi: 10.1007/s00592-024-02238-9. PMID: 38376579
Case report: Grönblad-Strandberg syndrome.
Cărăuș CV, Spînu AM, Negrii AA
Rom J Ophthalmol 2022 Apr-Jun;66(2):158-163. doi: 10.22336/rjo.2022.31. PMID: 35935090Free PMC Article
Mitochondrial Retinopathy.
Birtel J, von Landenberg C, Gliem M, Gliem C, Reimann J, Kunz WS, Herrmann P, Betz C, Caswell R, Nesbitt V, Kornblum C, Charbel Issa P
Ophthalmol Retina 2022 Jan;6(1):65-79. Epub 2021 Jul 10 doi: 10.1016/j.oret.2021.02.017. PMID: 34257060
Retinal Manifestations of Idiopathic Intracranial Hypertension.
Nichani P, Micieli JA
Ophthalmol Retina 2021 May;5(5):429-437. Epub 2020 Aug 26 doi: 10.1016/j.oret.2020.08.016. PMID: 32860958
Choroidal biomarkers.
Pichi F, Aggarwal K, Neri P, Salvetti P, Lembo A, Nucci P, Gemmy Cheung CM, Gupta V
Indian J Ophthalmol 2018 Dec;66(12):1716-1726. doi: 10.4103/ijo.IJO_893_18. PMID: 30451172Free PMC Article

Therapy

Application of Artificial Intelligence in Targeting Retinal Diseases.
Sorrentino FS, Jurman G, De Nadai K, Campa C, Furlanello C, Parmeggiani F
Curr Drug Targets 2020;21(12):1208-1215. doi: 10.2174/1389450121666200708120646. PMID: 32640954
Current management strategy of polypoidal choroidal vasculopathy.
Ho CPS, Lai TYY
Indian J Ophthalmol 2018 Dec;66(12):1727-1735. doi: 10.4103/ijo.IJO_975_18. PMID: 30451173Free PMC Article
Gene therapy for inherited retinal and optic nerve degenerations.
Moore NA, Morral N, Ciulla TA, Bracha P
Expert Opin Biol Ther 2018 Jan;18(1):37-49. Epub 2017 Oct 23 doi: 10.1080/14712598.2018.1389886. PMID: 29057663
Clinical characteristics and current therapies for inherited retinal degenerations.
Sahel JA, Marazova K, Audo I
Cold Spring Harb Perspect Med 2014 Oct 16;5(2):a017111. doi: 10.1101/cshperspect.a017111. PMID: 25324231Free PMC Article
Macular morphology and visual acuity in the comparison of age-related macular degeneration treatments trials.
Jaffe GJ, Martin DF, Toth CA, Daniel E, Maguire MG, Ying GS, Grunwald JE, Huang J; Comparison of Age-related Macular Degeneration Treatments Trials Research Group
Ophthalmology 2013 Sep;120(9):1860-70. Epub 2013 May 1 doi: 10.1016/j.ophtha.2013.01.073. PMID: 23642377Free PMC Article

Prognosis

Characteristics and Spatial Distribution of Structural Features in Age-Related Macular Degeneration: A MACUSTAR Study Report.
Saßmannshausen M, Behning C, Weinz J, Goerdt L, Terheyden JH, Chang P, Schmid M, Poor SH, Zakaria N, Finger RP, Holz FG, Pfau M, Schmitz-Valckenberg S, Thiele S; MACUSTAR Consortium Members
Ophthalmol Retina 2023 May;7(5):420-430. Epub 2022 Dec 20 doi: 10.1016/j.oret.2022.12.007. PMID: 36563964
Future perspectives for treating patients with geographic atrophy.
Loewenstein A, Trivizki O
Graefes Arch Clin Exp Ophthalmol 2023 Jun;261(6):1525-1531. Epub 2022 Dec 15 doi: 10.1007/s00417-022-05931-z. PMID: 36520185Free PMC Article
Retinal Manifestations of Idiopathic Intracranial Hypertension.
Nichani P, Micieli JA
Ophthalmol Retina 2021 May;5(5):429-437. Epub 2020 Aug 26 doi: 10.1016/j.oret.2020.08.016. PMID: 32860958
Predicting Progression of Age-Related Macular Degeneration Using OCT and Fundus Photography.
Wu Z, Bogunović H, Asgari R, Schmidt-Erfurth U, Guymer RH
Ophthalmol Retina 2021 Feb;5(2):118-125. Epub 2020 Jun 26 doi: 10.1016/j.oret.2020.06.026. PMID: 32599175
Nystagmus associated with macular dysplasia.
Wang FB
Strabismus 2020 Mar;28(1):17-19. Epub 2019 Sep 30 doi: 10.1080/09273972.2019.1668028. PMID: 31566469

Clinical prediction guides

Foveal Hypoplasia in CRB1-Related Retinopathies.
Rodriguez-Martinez AC, Higgins BE, Tailor-Hamblin V, Malka S, Cheloni R, Collins AM, Bladen J, Henderson R, Moosajee M
Int J Mol Sci 2023 Sep 11;24(18) doi: 10.3390/ijms241813932. PMID: 37762234Free PMC Article
Future perspectives for treating patients with geographic atrophy.
Loewenstein A, Trivizki O
Graefes Arch Clin Exp Ophthalmol 2023 Jun;261(6):1525-1531. Epub 2022 Dec 15 doi: 10.1007/s00417-022-05931-z. PMID: 36520185Free PMC Article
Multimodal imaging in pachychoroid spectrum.
Safi H, Ahmadieh H, Hassanpour K, Safi S
Surv Ophthalmol 2022 Mar-Apr;67(2):579-590. Epub 2021 Jul 29 doi: 10.1016/j.survophthal.2021.07.004. PMID: 34331955
Retinal Manifestations of Idiopathic Intracranial Hypertension.
Nichani P, Micieli JA
Ophthalmol Retina 2021 May;5(5):429-437. Epub 2020 Aug 26 doi: 10.1016/j.oret.2020.08.016. PMID: 32860958
Stemming retinal regeneration with pluripotent stem cells.
Jin ZB, Gao ML, Deng WL, Wu KC, Sugita S, Mandai M, Takahashi M
Prog Retin Eye Res 2019 Mar;69:38-56. Epub 2018 Nov 9 doi: 10.1016/j.preteyeres.2018.11.003. PMID: 30419340

Recent systematic reviews

Retina as a potential biomarker in schizophrenia spectrum disorders: a systematic review and meta-analysis of optical coherence tomography and electroretinography.
Komatsu H, Onoguchi G, Silverstein SM, Jerotic S, Sakuma A, Kanahara N, Kakuto Y, Ono T, Yabana T, Nakazawa T, Tomita H
Mol Psychiatry 2024 Feb;29(2):464-482. Epub 2023 Dec 11 doi: 10.1038/s41380-023-02340-4. PMID: 38081943Free PMC Article
A Systematic Review of the Clinical Manifestations and Diagnostic Methods for Macular Coloboma.
Hou X, Guo Y, Liu J, Li S, Fan W, Lin M, Rokohl AC, Heindl LM
Curr Eye Res 2021 Jul;46(7):913-918. Epub 2021 Jan 22 doi: 10.1080/02713683.2020.1853779. PMID: 33478254
Surgical Options and Outcomes in the Treatment of Optic Pit Maculopathy: A Meta-analysis and Systematic Review.
Zheng A, Singh RP, Lavine JA
Ophthalmol Retina 2020 Mar;4(3):289-299. Epub 2019 Nov 21 doi: 10.1016/j.oret.2019.10.011. PMID: 31937471

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