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Gastroenteritides, Swine Transmissible

MedGen UID:
8969
•Concept ID:
C0017162
•
Disease or Syndrome
Synonyms: Gastroenteritides, Porcine Transmissible; Gastroenteritides, Transmissible Porcine; Gastroenteritis, Porcine Transmissible; Gastroenteritis, Swine Transmissible; Gastroenteritis, Transmissible Porcine; Gastroenteritis, Transmissible, of Swine; Gastroenteritis, Transmissible, Porcine; Porcine Gastroenteritides, Transmissible; Porcine Gastroenteritis, Transmissible; Porcine Transmissible Gastroenteritides; Porcine Transmissible Gastroenteritis; Swine Transmissible Gastroenteritides; Swine Transmissible Gastroenteritis; Transmissible Gastroenteritides, Porcine; Transmissible Gastroenteritides, Swine; Transmissible Gastroenteritis of Swine; Transmissible Gastroenteritis, Porcine; Transmissible Gastroenteritis, Swine; Transmissible Porcine Gastroenteritides; Transmissible Porcine Gastroenteritis

Definition

A condition of chronic gastroenteritis in adult pigs and fatal gastroenteritis in piglets caused by a CORONAVIRUS. [from MeSH]

Term Hierarchy

CClinical test,  RResearch test,  OOMIM,  GGeneReviews,  VClinVar  
  • CROGVGastroenteritides, Swine Transmissible

Professional guidelines

PubMed

Risk Assessment of the Possible Intermediate Host Role of Pigs for Coronaviruses with a Deep Learning Predictor.
Jiang S, Zhang S, Kang X, Feng Y, Li Y, Nie M, Li Y, Chen Y, Zhao S, Jiang T, Li J
Viruses 2023 Jul 15;15(7) doi: 10.3390/v15071556. PMID: 37515242Free PMC Article

Recent clinical studies

Etiology

Risk Assessment of the Possible Intermediate Host Role of Pigs for Coronaviruses with a Deep Learning Predictor.
Jiang S, Zhang S, Kang X, Feng Y, Li Y, Nie M, Li Y, Chen Y, Zhao S, Jiang T, Li J
Viruses 2023 Jul 15;15(7) doi: 10.3390/v15071556. PMID: 37515242Free PMC Article
Transmissible Gastroenteritis Virus: An Update Review and Perspective.
Chen Y, Zhang Y, Wang X, Zhou J, Ma L, Li J, Yang L, Ouyang H, Yuan H, Pang D
Viruses 2023 Jan 27;15(2) doi: 10.3390/v15020359. PMID: 36851573Free PMC Article
Naturally Occurring Animal Coronaviruses as Models for Studying Highly Pathogenic Human Coronaviral Disease.
Kenney SP, Wang Q, Vlasova A, Jung K, Saif L
Vet Pathol 2021 May;58(3):438-452. Epub 2020 Dec 28 doi: 10.1177/0300985820980842. PMID: 33357102
Viral strategies for triggering and manipulating mitophagy.
Zhang L, Qin Y, Chen M
Autophagy 2018;14(10):1665-1673. Epub 2018 Aug 16 doi: 10.1080/15548627.2018.1466014. PMID: 29895192Free PMC Article
Porcine innate and adaptative immune responses to influenza and coronavirus infections.
Charley B, Riffault S, Van Reeth K
Ann N Y Acad Sci 2006 Oct;1081(1):130-6. doi: 10.1196/annals.1373.014. PMID: 17135502Free PMC Article

Diagnosis

A novel approach to concentrate human and animal viruses from wastewater using receptors-conjugated magnetic beads.
Oh C, Kim K, Araud E, Wang L, Shisler JL, Nguyen TH
Water Res 2022 Apr 1;212:118112. Epub 2022 Jan 20 doi: 10.1016/j.watres.2022.118112. PMID: 35091223
Porcine enteric coronaviruses: an updated overview of the pathogenesis, prevalence, and diagnosis.
Liu Q, Wang HY
Vet Res Commun 2021 Sep;45(2-3):75-86. Epub 2021 Jul 12 doi: 10.1007/s11259-021-09808-0. PMID: 34251560Free PMC Article
The emerging role and significance of circular RNAs in viral infections and antiviral immune responses: possible implication as theranostic agents.
Awan FM, Yang BB, Naz A, Hanif A, Ikram A, Obaid A, Malik A, Janjua HA, Ali A, Sharif S
RNA Biol 2021 Jan;18(1):1-15. Epub 2020 Jul 13 doi: 10.1080/15476286.2020.1790198. PMID: 32615049Free PMC Article
Development of a one-step RT-PCR assay for detection of pancoronaviruses (α-, β-, γ-, and δ-coronaviruses) using newly designed degenerate primers for porcine and avian `fecal samples.
Hu H, Jung K, Wang Q, Saif LJ, Vlasova AN
J Virol Methods 2018 Jun;256:116-122. Epub 2018 Feb 27 doi: 10.1016/j.jviromet.2018.02.021. PMID: 29499225Free PMC Article
Recent developments in viral gastroenteritis.
Hamilton JR, Gall DG, Kerzner B, Butler DG, Middleton PJ
Pediatr Clin North Am 1975 Nov;22(4):747-55. doi: 10.1016/s0031-3955(16)33205-9. PMID: 1105359Free PMC Article

Therapy

Generation and Characterization of Monoclonal Antibody Against Porcine Epidemic Diarrhea Virus Nonstructural Protein 13.
Chen J, Ding T, Liang W, Li T, Wu S, Xie W, Ding N, Tang Y, Ding Z
Monoclon Antib Immunodiagn Immunother 2020 Dec;39(6):222-227. doi: 10.1089/mab.2020.0028. PMID: 33351712
Contribution of the porcine aminopeptidase N (CD13) receptor density to porcine epidemic diarrhea virus infection.
Nam E, Lee C
Vet Microbiol 2010 Jul 29;144(1-2):41-50. Epub 2009 Dec 28 doi: 10.1016/j.vetmic.2009.12.024. PMID: 20074871Free PMC Article
An antibody derivative expressed from viral vectors passively immunizes pigs against transmissible gastroenteritis virus infection when supplied orally in crude plant extracts.
Monger W, Alamillo JM, Sola I, Perrin Y, Bestagno M, Burrone OR, Sabella P, Plana-Duran J, Enjuanes L, Garcia JA, Lomonossoff GP
Plant Biotechnol J 2006 Nov;4(6):623-31. doi: 10.1111/j.1467-7652.2006.00206.x. PMID: 17309733Free PMC Article
Mucosal immunization using recombinant plant-based oral vaccines.
Streatfield SJ
Methods 2006 Feb;38(2):150-7. doi: 10.1016/j.ymeth.2005.09.013. PMID: 16431131
Comments on the pathogenesis of transmissible gastroenteritis of swine.
Hooper BE
J Am Vet Med Assoc 1972 Feb 15;160(4):540-2. PMID: 4624104

Prognosis

Risk Assessment of the Possible Intermediate Host Role of Pigs for Coronaviruses with a Deep Learning Predictor.
Jiang S, Zhang S, Kang X, Feng Y, Li Y, Nie M, Li Y, Chen Y, Zhao S, Jiang T, Li J
Viruses 2023 Jul 15;15(7) doi: 10.3390/v15071556. PMID: 37515242Free PMC Article
JIB-04 Has Broad-Spectrum Antiviral Activity and Inhibits SARS-CoV-2 Replication and Coronavirus Pathogenesis.
Son J, Huang S, Zeng Q, Bricker TL, Case JB, Zhou J, Zang R, Liu Z, Chang X, Darling TL, Xu J, Harastani HH, Chen L, Gomez Castro MF, Zhao Y, Kohio HP, Hou G, Fan B, Niu B, Guo R, Rothlauf PW, Bailey AL, Wang X, Shi PY, Martinez ED, Brody SL, Whelan SPJ, Diamond MS, Boon ACM, Li B, Ding S
mBio 2022 Feb 22;13(1):e0337721. Epub 2022 Jan 18 doi: 10.1128/mbio.03377-21. PMID: 35038906Free PMC Article
Conservation of substrate specificities among coronavirus main proteases.
Hegyi A, Ziebuhr J
J Gen Virol 2002 Mar;83(Pt 3):595-599. doi: 10.1099/0022-1317-83-3-595. PMID: 11842254
Feline aminopeptidase N serves as a receptor for feline, canine, porcine, and human coronaviruses in serogroup I.
Tresnan DB, Levis R, Holmes KV
J Virol 1996 Dec;70(12):8669-74. doi: 10.1128/JVI.70.12.8669-8674.1996. PMID: 8970993Free PMC Article
Genomic organization and expression of the 3' end of the canine and feline enteric coronaviruses.
Vennema H, Rossen JW, Wesseling J, Horzinek MC, Rottier PJ
Adv Exp Med Biol 1993;342:11-6. doi: 10.1007/978-1-4615-2996-5_2. PMID: 8209715

Clinical prediction guides

Risk Assessment of the Possible Intermediate Host Role of Pigs for Coronaviruses with a Deep Learning Predictor.
Jiang S, Zhang S, Kang X, Feng Y, Li Y, Nie M, Li Y, Chen Y, Zhao S, Jiang T, Li J
Viruses 2023 Jul 15;15(7) doi: 10.3390/v15071556. PMID: 37515242Free PMC Article
Transmissible Gastroenteritis Virus: An Update Review and Perspective.
Chen Y, Zhang Y, Wang X, Zhou J, Ma L, Li J, Yang L, Ouyang H, Yuan H, Pang D
Viruses 2023 Jan 27;15(2) doi: 10.3390/v15020359. PMID: 36851573Free PMC Article
Persistence Infection of TGEV Promotes Enterococcus faecalis Infection on IPEC-J2 Cells.
Guo Z, Zhang C, Dong J, Wang Y, Hu H, Chen L
Int J Mol Sci 2022 Dec 27;24(1) doi: 10.3390/ijms24010450. PMID: 36613893Free PMC Article
Swine coronaviruses (SCoVs) and their emerging threats to swine population, inter-species transmission, exploring the susceptibility of pigs for SARS-CoV-2 and zoonotic concerns.
Thakor JC, Dinesh M, Manikandan R, Bindu S, Sahoo M, Sahoo D, Dhawan M, Pandey MK, Tiwari R, Emran TB, Dhama K, Chaicumpa W
Vet Q 2022 Dec;42(1):125-147. doi: 10.1080/01652176.2022.2079756. PMID: 35584308Free PMC Article
Aminopeptidase N is not required for porcine epidemic diarrhea virus cell entry.
Li W, Luo R, He Q, van Kuppeveld FJM, Rottier PJM, Bosch BJ
Virus Res 2017 May 2;235:6-13. Epub 2017 Mar 28 doi: 10.1016/j.virusres.2017.03.018. PMID: 28363778Free PMC Article

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