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Third Trimester Antepartum Hemorrhage

MedGen UID:
897740
•Concept ID:
C4086902
•
Pathologic Function
Synonym: Antepartum Hemorrhage, Third Trimester

Definition

Excessive blood loss within the third trimester but prior to onset of labor. [from NCI]

Term Hierarchy

CClinical test,  RResearch test,  OOMIM,  GGeneReviews,  VClinVar  
  • CROGVThird Trimester Antepartum Hemorrhage

Professional guidelines

PubMed

Implementation of a protocol for management of antepartum iron deficiency anemia: a prospective cohort study.
Hamm RF, Wang EY, Levine LD, Speranza RJ, Srinivas SK
Am J Obstet Gynecol MFM 2022 Mar;4(2):100533. Epub 2021 Nov 20 doi: 10.1016/j.ajogmf.2021.100533. PMID: 34808403Free PMC Article
Management of parturients with Factor XI deficiency-10year case series and review of literature.
Verghese L, Tingi E, Thachil J, Hay C, Byrd L
Eur J Obstet Gynecol Reprod Biol 2017 Aug;215:85-92. Epub 2017 Jun 6 doi: 10.1016/j.ejogrb.2017.06.008. PMID: 28622635
Amnioinfusion in the management of oligohydramnios.
Gramellini D, Piantelli G, Delle Chiaie L, Rutolo S, Vadora E
J Perinat Med 1998;26(4):293-301. doi: 10.1515/jpme.1998.26.4.293. PMID: 9846304

Recent clinical studies

Therapy

The Risk of Obstetrical Hemorrhage in Placenta Praevia Associated with Coronavirus Infection Antepartum or Intrapartum.
Pacu I, Zygouropoulos N, Cristea AE, Zaharia C, Rosu GA, Matei A, Bodei LT, Neacsu A, Ionescu CA
Medicina (Kaunas) 2022 Jul 27;58(8) doi: 10.3390/medicina58081004. PMID: 36013471Free PMC Article
Considering delay of cholecystectomy in the third trimester of pregnancy.
Hong J, Yang J, Zhang X, Su J, Tumati A, Garry D, Docimo S, Bates AT, Spaniolas K, Talamini MA, Pryor AD
Surg Endosc 2021 Aug;35(8):4673-4680. Epub 2020 Sep 1 doi: 10.1007/s00464-020-07910-z. PMID: 32875420
The association between maternal cortisol and depression during pregnancy, a systematic review.
Orta OR, Gelaye B, Bain PA, Williams MA
Arch Womens Ment Health 2018 Feb;21(1):43-53. Epub 2017 Sep 24 doi: 10.1007/s00737-017-0777-y. PMID: 28942465Free PMC Article
Management of parturients with Factor XI deficiency-10year case series and review of literature.
Verghese L, Tingi E, Thachil J, Hay C, Byrd L
Eur J Obstet Gynecol Reprod Biol 2017 Aug;215:85-92. Epub 2017 Jun 6 doi: 10.1016/j.ejogrb.2017.06.008. PMID: 28622635
Cesarean scar pregnancy is a precursor of morbidly adherent placenta.
Timor-Tritsch IE, Monteagudo A, Cali G, Vintzileos A, Viscarello R, Al-Khan A, Zamudio S, Mayberry P, Cordoba MM, Dar P
Ultrasound Obstet Gynecol 2014 Sep;44(3):346-53. Epub 2014 Jul 31 doi: 10.1002/uog.13426. PMID: 24890256

Prognosis

Maternal and Perinatal Morbidity and Mortality Associated With Anemia in Pregnancy.
Smith C, Teng F, Branch E, Chu S, Joseph KS
Obstet Gynecol 2019 Dec;134(6):1234-1244. doi: 10.1097/AOG.0000000000003557. PMID: 31764734Free PMC Article
Cesarean scar pregnancy is a precursor of morbidly adherent placenta.
Timor-Tritsch IE, Monteagudo A, Cali G, Vintzileos A, Viscarello R, Al-Khan A, Zamudio S, Mayberry P, Cordoba MM, Dar P
Ultrasound Obstet Gynecol 2014 Sep;44(3):346-53. Epub 2014 Jul 31 doi: 10.1002/uog.13426. PMID: 24890256
Cervical length and risk of antepartum hemorrhage in presence of low-lying placenta.
Curti A, Potti S, Di Donato N, Simonazzi G, Rizzo N, Berghella V
J Matern Fetal Neonatal Med 2013 Apr;26(6):563-5. Epub 2012 Dec 12 doi: 10.3109/14767058.2012.743524. PMID: 23153020
Antepartum bleeding of unknown origin in the second half of pregnancy: a review.
Magann EF, Cummings JE, Niederhauser A, Rodriguez-Thompson D, McCormack R, Chauhan SP
Obstet Gynecol Surv 2005 Nov;60(11):741-5. doi: 10.1097/01.ogx.0000182881.53139.f7. PMID: 16250922
C-reactive protein in normal pregnancy.
Watts DH, Krohn MA, Wener MH, Eschenbach DA
Obstet Gynecol 1991 Feb;77(2):176-80. doi: 10.1097/00006250-199102000-00002. PMID: 1988876

Clinical prediction guides

Antepartum and postpartum changes in adipokines, endothelial dysfunction, inflammatory markers and other biochemical parameters in preeclamptic women: A prospective observational cohort study.
Talab AY, Aboali Hamza H, Mostafa TM
J Appl Biomed 2021 Mar;19(1):62-72. Epub 2021 Jan 28 doi: 10.32725/jab.2021.004. PMID: 34907717
Maternal and Perinatal Morbidity and Mortality Associated With Anemia in Pregnancy.
Smith C, Teng F, Branch E, Chu S, Joseph KS
Obstet Gynecol 2019 Dec;134(6):1234-1244. doi: 10.1097/AOG.0000000000003557. PMID: 31764734Free PMC Article
The association between maternal cortisol and depression during pregnancy, a systematic review.
Orta OR, Gelaye B, Bain PA, Williams MA
Arch Womens Ment Health 2018 Feb;21(1):43-53. Epub 2017 Sep 24 doi: 10.1007/s00737-017-0777-y. PMID: 28942465Free PMC Article
Maternal Serum Prolactin and Prediction of Postpartum β-Cell Function and Risk of Prediabetes/Diabetes.
Retnakaran R, Ye C, Kramer CK, Connelly PW, Hanley AJ, Sermer M, Zinman B
Diabetes Care 2016 Jul;39(7):1250-8. Epub 2016 Apr 26 doi: 10.2337/dc16-0043. PMID: 27208323
Antepartum bleeding of unknown origin in the second half of pregnancy: a review.
Magann EF, Cummings JE, Niederhauser A, Rodriguez-Thompson D, McCormack R, Chauhan SP
Obstet Gynecol Surv 2005 Nov;60(11):741-5. doi: 10.1097/01.ogx.0000182881.53139.f7. PMID: 16250922

Recent systematic reviews

The association between maternal cortisol and depression during pregnancy, a systematic review.
Orta OR, Gelaye B, Bain PA, Williams MA
Arch Womens Ment Health 2018 Feb;21(1):43-53. Epub 2017 Sep 24 doi: 10.1007/s00737-017-0777-y. PMID: 28942465Free PMC Article

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