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Preterm intraventricular hemorrhage

MedGen UID:
904936
•Concept ID:
C4280789
•
Pathologic Function
Synonym: Preterm intraventricular haemorrhage
 
HPO: HP:0030747

Definition

Intraventricular hemorrhage that occurs in a premature infant. [from HPO]

Professional guidelines

PubMed

Less invasive surfactant administration versus intubation-surfactant-extubation in the treatment of neonatal respiratory distress syndrome: a systematic review and meta-analyses.
Silveira RC, Panceri C, Munõz NP, Carvalho MB, Fraga AC, Procianoy RS
J Pediatr (Rio J) 2024 Jan-Feb;100(1):8-24. Epub 2023 Jun 21 doi: 10.1016/j.jped.2023.05.008. PMID: 37353207Free PMC Article
Impact of early screening echocardiography and targeted PDA treatment on neonatal outcomes in "22-23" week and "24-26" infants.
Giesinger RE, Hobson AA, Bischoff AR, Klein JM, McNamara PJ
Semin Perinatol 2023 Mar;47(2):151721. Epub 2023 Mar 5 doi: 10.1016/j.semperi.2023.151721. PMID: 36882362
Treatment of Posthemorrhagic Hydrocephalus.
Cohen S, Flibotte J
Clin Perinatol 2022 Mar;49(1):15-25. Epub 2022 Jan 21 doi: 10.1016/j.clp.2021.11.002. PMID: 35209998

Recent clinical studies

Etiology

Reducing Severe Intraventricular Hemorrhage in Preterm Infants With Improved Care Bundle Adherence.
Kolnik SE, Upadhyay K, Wood TR, Juul SE, Valentine GC
Pediatrics 2023 Sep 1;152(3) doi: 10.1542/peds.2021-056104. PMID: 37609772
Impact of Early Hemodynamic Screening on Extremely Preterm Outcomes in a High-Performance Center.
Giesinger RE, Rios DR, Chatmethakul T, Bischoff AR, Sandgren JA, Cunningham A, Beauchene M, Stanford AH, Klein JM, Ten Eyck P, McNamara PJ
Am J Respir Crit Care Med 2023 Aug 1;208(3):290-300. doi: 10.1164/rccm.202212-2291OC. PMID: 37209133Free PMC Article
Cranial ultrasound findings in preterm germinal matrix haemorrhage, sequelae and outcome.
Parodi A, Govaert P, Horsch S, Bravo MC, Ramenghi LA; eurUS.brain group
Pediatr Res 2020 Mar;87(Suppl 1):13-24. doi: 10.1038/s41390-020-0780-2. PMID: 32218535Free PMC Article
Preterm brain injury: Germinal matrix-intraventricular hemorrhage and post-hemorrhagic ventricular dilatation.
Leijser LM, de Vries LS
Handb Clin Neurol 2019;162:173-199. doi: 10.1016/B978-0-444-64029-1.00008-4. PMID: 31324310
Early versus delayed umbilical cord clamping on maternal and neonatal outcomes.
Qian Y, Ying X, Wang P, Lu Z, Hua Y
Arch Gynecol Obstet 2019 Sep;300(3):531-543. Epub 2019 Jun 15 doi: 10.1007/s00404-019-05215-8. PMID: 31203386Free PMC Article

Diagnosis

Severity of Bronchopulmonary Dysplasia Among Very Preterm Infants in the United States.
Jensen EA, Edwards EM, Greenberg LT, Soll RF, Ehret DEY, Horbar JD
Pediatrics 2021 Jul;148(1) Epub 2021 Jun 2 doi: 10.1542/peds.2020-030007. PMID: 34078747Free PMC Article
Randomized Controlled Early versus Late Ventricular Intervention Study in Posthemorrhagic Ventricular Dilatation: Outcome at 2 Years.
Cizmeci MN, Groenendaal F, Liem KD, van Haastert IC, Benavente-Fernández I, van Straaten HLM, Steggerda S, Smit BJ, Whitelaw A, Woerdeman P, Heep A, de Vries LS; ELVIS study group
J Pediatr 2020 Nov;226:28-35.e3. Epub 2020 Aug 12 doi: 10.1016/j.jpeds.2020.08.014. PMID: 32800815
Effect of timing of umbilical cord clamping and other strategies to influence placental transfusion at preterm birth on maternal and infant outcomes.
Rabe H, Gyte GM, Díaz-Rossello JL, Duley L
Cochrane Database Syst Rev 2019 Sep 17;9(9):CD003248. doi: 10.1002/14651858.CD003248.pub4. PMID: 31529790Free PMC Article
Association of Placebo, Indomethacin, Ibuprofen, and Acetaminophen With Closure of Hemodynamically Significant Patent Ductus Arteriosus in Preterm Infants: A Systematic Review and Meta-analysis.
Mitra S, Florez ID, Tamayo ME, Mbuagbaw L, Vanniyasingam T, Veroniki AA, Zea AM, Zhang Y, Sadeghirad B, Thabane L
JAMA 2018 Mar 27;319(12):1221-1238. doi: 10.1001/jama.2018.1896. PMID: 29584842Free PMC Article
Neurosonography: Assessing the Premature Infant.
Maller VV, Cohen HL
Pediatr Radiol 2017 Aug;47(9):1031-1045. Epub 2017 Aug 4 doi: 10.1007/s00247-017-3884-z. PMID: 28779189

Therapy

Effect of Enteral Lipid Supplement on Severe Retinopathy of Prematurity: A Randomized Clinical Trial.
Hellström A, Nilsson AK, Wackernagel D, Pivodic A, Vanpee M, Sjöbom U, Hellgren G, Hallberg B, Domellöf M, Klevebro S, Hellström W, Andersson M, Lund AM, Löfqvist C, Elfvin A, Sävman K, Hansen-Pupp I, Hård AL, Smith LEH, Ley D
JAMA Pediatr 2021 Apr 1;175(4):359-367. doi: 10.1001/jamapediatrics.2020.5653. PMID: 33523106Free PMC Article
Antenatal corticosteroids for accelerating fetal lung maturation for women at risk of preterm birth.
McGoldrick E, Stewart F, Parker R, Dalziel SR
Cochrane Database Syst Rev 2020 Dec 25;12(12):CD004454. doi: 10.1002/14651858.CD004454.pub4. PMID: 33368142Free PMC Article
Association of Umbilical Cord Milking vs Delayed Umbilical Cord Clamping With Death or Severe Intraventricular Hemorrhage Among Preterm Infants.
Katheria A, Reister F, Essers J, Mendler M, Hummler H, Subramaniam A, Carlo W, Tita A, Truong G, Davis-Nelson S, Schmölzer G, Chari R, Kaempf J, Tomlinson M, Yanowitz T, Beck S, Simhan H, Dempsey E, O'Donoghue K, Bhat S, Hoffman M, Faksh A, Arnell K, Rich W, Finer N, Vaucher Y, Khanna P, Meyers M, Varner M, Allman P, Szychowski J, Cutter G
JAMA 2019 Nov 19;322(19):1877-1886. doi: 10.1001/jama.2019.16004. PMID: 31742630Free PMC Article
Association of Placebo, Indomethacin, Ibuprofen, and Acetaminophen With Closure of Hemodynamically Significant Patent Ductus Arteriosus in Preterm Infants: A Systematic Review and Meta-analysis.
Mitra S, Florez ID, Tamayo ME, Mbuagbaw L, Vanniyasingam T, Veroniki AA, Zea AM, Zhang Y, Sadeghirad B, Thabane L
JAMA 2018 Mar 27;319(12):1221-1238. doi: 10.1001/jama.2018.1896. PMID: 29584842Free PMC Article
Delayed vs early umbilical cord clamping for preterm infants: a systematic review and meta-analysis.
Fogarty M, Osborn DA, Askie L, Seidler AL, Hunter K, Lui K, Simes J, Tarnow-Mordi W
Am J Obstet Gynecol 2018 Jan;218(1):1-18. Epub 2017 Oct 30 doi: 10.1016/j.ajog.2017.10.231. PMID: 29097178

Prognosis

Trends in Mortality and Morbidities for Infants Born 24 to 28 Weeks in the US: 1997-2021.
Horbar JD, Greenberg LT, Buzas JS, Ehret DEY, Soll RF, Edwards EM
Pediatrics 2024 Jan 1;153(1) doi: 10.1542/peds.2023-064153. PMID: 38053449
Intraventricular Hemorrhage in Very Preterm Children: Mortality and Neurodevelopment at Age 5.
Tréluyer L, Chevallier M, Jarreau PH, Baud O, Benhammou V, Gire C, Marchand-Martin L, Marret S, Pierrat V, Ancel PY, Torchin H
Pediatrics 2023 Apr 1;151(4) doi: 10.1542/peds.2022-059138. PMID: 36919442Free PMC Article
Severity of Bronchopulmonary Dysplasia Among Very Preterm Infants in the United States.
Jensen EA, Edwards EM, Greenberg LT, Soll RF, Ehret DEY, Horbar JD
Pediatrics 2021 Jul;148(1) Epub 2021 Jun 2 doi: 10.1542/peds.2020-030007. PMID: 34078747Free PMC Article
Cranial ultrasound findings in preterm germinal matrix haemorrhage, sequelae and outcome.
Parodi A, Govaert P, Horsch S, Bravo MC, Ramenghi LA; eurUS.brain group
Pediatr Res 2020 Mar;87(Suppl 1):13-24. doi: 10.1038/s41390-020-0780-2. PMID: 32218535Free PMC Article
Neonatal care bundles are associated with a reduction in the incidence of intraventricular haemorrhage in preterm infants: a multicentre cohort study.
de Bijl-Marcus K, Brouwer AJ, De Vries LS, Groenendaal F, Wezel-Meijler GV
Arch Dis Child Fetal Neonatal Ed 2020 Jul;105(4):419-424. Epub 2019 Nov 15 doi: 10.1136/archdischild-2018-316692. PMID: 31732682

Clinical prediction guides

Reducing Severe Intraventricular Hemorrhage in Preterm Infants With Improved Care Bundle Adherence.
Kolnik SE, Upadhyay K, Wood TR, Juul SE, Valentine GC
Pediatrics 2023 Sep 1;152(3) doi: 10.1542/peds.2021-056104. PMID: 37609772
Cranial ultrasound findings in preterm germinal matrix haemorrhage, sequelae and outcome.
Parodi A, Govaert P, Horsch S, Bravo MC, Ramenghi LA; eurUS.brain group
Pediatr Res 2020 Mar;87(Suppl 1):13-24. doi: 10.1038/s41390-020-0780-2. PMID: 32218535Free PMC Article
Neonatal care bundles are associated with a reduction in the incidence of intraventricular haemorrhage in preterm infants: a multicentre cohort study.
de Bijl-Marcus K, Brouwer AJ, De Vries LS, Groenendaal F, Wezel-Meijler GV
Arch Dis Child Fetal Neonatal Ed 2020 Jul;105(4):419-424. Epub 2019 Nov 15 doi: 10.1136/archdischild-2018-316692. PMID: 31732682
Association of Umbilical Cord Milking vs Delayed Umbilical Cord Clamping With Death or Severe Intraventricular Hemorrhage Among Preterm Infants.
Katheria A, Reister F, Essers J, Mendler M, Hummler H, Subramaniam A, Carlo W, Tita A, Truong G, Davis-Nelson S, Schmölzer G, Chari R, Kaempf J, Tomlinson M, Yanowitz T, Beck S, Simhan H, Dempsey E, O'Donoghue K, Bhat S, Hoffman M, Faksh A, Arnell K, Rich W, Finer N, Vaucher Y, Khanna P, Meyers M, Varner M, Allman P, Szychowski J, Cutter G
JAMA 2019 Nov 19;322(19):1877-1886. doi: 10.1001/jama.2019.16004. PMID: 31742630Free PMC Article
Early versus delayed umbilical cord clamping on maternal and neonatal outcomes.
Qian Y, Ying X, Wang P, Lu Z, Hua Y
Arch Gynecol Obstet 2019 Sep;300(3):531-543. Epub 2019 Jun 15 doi: 10.1007/s00404-019-05215-8. PMID: 31203386Free PMC Article

Recent systematic reviews

Interventions for patent ductus arteriosus (PDA) in preterm infants: an overview of Cochrane Systematic Reviews.
Mitra S, de Boode WP, Weisz DE, Shah PS
Cochrane Database Syst Rev 2023 Apr 11;4(4):CD013588. doi: 10.1002/14651858.CD013588.pub2. PMID: 37039501Free PMC Article
Antenatal corticosteroids for accelerating fetal lung maturation for women at risk of preterm birth.
McGoldrick E, Stewart F, Parker R, Dalziel SR
Cochrane Database Syst Rev 2020 Dec 25;12(12):CD004454. doi: 10.1002/14651858.CD004454.pub4. PMID: 33368142Free PMC Article
Association of Placebo, Indomethacin, Ibuprofen, and Acetaminophen With Closure of Hemodynamically Significant Patent Ductus Arteriosus in Preterm Infants: A Systematic Review and Meta-analysis.
Mitra S, Florez ID, Tamayo ME, Mbuagbaw L, Vanniyasingam T, Veroniki AA, Zea AM, Zhang Y, Sadeghirad B, Thabane L
JAMA 2018 Mar 27;319(12):1221-1238. doi: 10.1001/jama.2018.1896. PMID: 29584842Free PMC Article
Delayed vs early umbilical cord clamping for preterm infants: a systematic review and meta-analysis.
Fogarty M, Osborn DA, Askie L, Seidler AL, Hunter K, Lui K, Simes J, Tarnow-Mordi W
Am J Obstet Gynecol 2018 Jan;218(1):1-18. Epub 2017 Oct 30 doi: 10.1016/j.ajog.2017.10.231. PMID: 29097178
Antenatal corticosteroids for accelerating fetal lung maturation for women at risk of preterm birth.
Roberts D, Brown J, Medley N, Dalziel SR
Cochrane Database Syst Rev 2017 Mar 21;3(3):CD004454. doi: 10.1002/14651858.CD004454.pub3. PMID: 28321847Free PMC Article

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