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Grade IV preterm intraventricular hemorrhage

MedGen UID:
905239
•Concept ID:
C4280786
•
Pathologic Function
Synonym: Grade IV preterm intraventricular haemorrhage
 
HPO: HP:0030751

Definition

Intraventricular hemorrhage that occurs in a preterm infant and that shows parenchymal extension. [from HPO]

Term Hierarchy

CClinical test,  RResearch test,  OOMIM,  GGeneReviews,  VClinVar  
  • CROGVGrade IV preterm intraventricular hemorrhage

Professional guidelines

PubMed

Ventriculosubgaleal shunt and neuroendoscopic lavage: refining the treatment algorithm of neonatal post-hemorrhagic hydrocephalus.
Frassanito P, Serrao F, Gallini F, Bianchi F, Massimi L, Vento G, Tamburrini G
Childs Nerv Syst 2021 Nov;37(11):3531-3540. Epub 2021 May 20 doi: 10.1007/s00381-021-05216-6. PMID: 34014368Free PMC Article
Surgical treatment of posthemorrhagic infantile hydrocephalus.
Massimi L, Di Rocco C
Minerva Pediatr 2013 Aug;65(4):417-25. PMID: 24051975
Bronchodilators for the prevention and treatment of chronic lung disease in preterm infants.
Ng GY, da S, Ohlsson A
Cochrane Database Syst Rev 2001;(3):CD003214. doi: 10.1002/14651858.CD003214. PMID: 11687053

Recent clinical studies

Etiology

Retinopathy of prematurity screening: prevalence and risk factors of ophthalmic complications in non-treated preterm infants.
Strelnikov JI, Rao R, Majidi S, Lueder G, Lee A, Reynolds MM
Eye (Lond) 2024 Jun;38(8):1462-1470. Epub 2024 Jan 11 doi: 10.1038/s41433-023-02921-1. PMID: 38212403Free PMC Article
Reducing Severe Intraventricular Hemorrhage in Preterm Infants With Improved Care Bundle Adherence.
Kolnik SE, Upadhyay K, Wood TR, Juul SE, Valentine GC
Pediatrics 2023 Sep 1;152(3) doi: 10.1542/peds.2021-056104. PMID: 37609772
Interventions for patent ductus arteriosus (PDA) in preterm infants: an overview of Cochrane Systematic Reviews.
Mitra S, de Boode WP, Weisz DE, Shah PS
Cochrane Database Syst Rev 2023 Apr 11;4(4):CD013588. doi: 10.1002/14651858.CD013588.pub2. PMID: 37039501Free PMC Article
Fetal Urine Production Rate in Preterm Premature Rupture of Membranes Is Associated with Adverse Neonatal Outcome: A Pilot Study.
Avitan T, Drukker L, Pri-Chen H, Rabinowitz R, Algur N, Schimmel MS, Schreiber L, Bdolah-Abram T, Samueloff A, Grisaru-Granovsky S
Gynecol Obstet Invest 2018;83(1):57-64. Epub 2017 Jul 18 doi: 10.1159/000478778. PMID: 28715801
Early developmental intervention programmes provided post hospital discharge to prevent motor and cognitive impairment in preterm infants.
Spittle A, Orton J, Anderson PJ, Boyd R, Doyle LW
Cochrane Database Syst Rev 2015 Nov 24;2015(11):CD005495. doi: 10.1002/14651858.CD005495.pub4. PMID: 26597166Free PMC Article

Diagnosis

Retinopathy of prematurity screening: prevalence and risk factors of ophthalmic complications in non-treated preterm infants.
Strelnikov JI, Rao R, Majidi S, Lueder G, Lee A, Reynolds MM
Eye (Lond) 2024 Jun;38(8):1462-1470. Epub 2024 Jan 11 doi: 10.1038/s41433-023-02921-1. PMID: 38212403Free PMC Article
Low-Grade Intraventricular Hemorrhage and Neurodevelopmental Outcomes at 24-42 Months of Age.
Scott TE, Aboudi D, Kase JS
J Child Neurol 2020 Aug;35(9):578-584. Epub 2020 May 21 doi: 10.1177/0883073820922638. PMID: 32438867
Fetal Urine Production Rate in Preterm Premature Rupture of Membranes Is Associated with Adverse Neonatal Outcome: A Pilot Study.
Avitan T, Drukker L, Pri-Chen H, Rabinowitz R, Algur N, Schimmel MS, Schreiber L, Bdolah-Abram T, Samueloff A, Grisaru-Granovsky S
Gynecol Obstet Invest 2018;83(1):57-64. Epub 2017 Jul 18 doi: 10.1159/000478778. PMID: 28715801
Early developmental intervention programmes provided post hospital discharge to prevent motor and cognitive impairment in preterm infants.
Spittle A, Orton J, Anderson PJ, Boyd R, Doyle LW
Cochrane Database Syst Rev 2015 Nov 24;2015(11):CD005495. doi: 10.1002/14651858.CD005495.pub4. PMID: 26597166Free PMC Article
Intraventricular hemorrhage in the preterm infant.
Vohr B, Ment LR
Early Hum Dev 1996 Jan 5;44(1):1-16. doi: 10.1016/0378-3782(95)01692-9. PMID: 8821891

Therapy

Umbilical Cord Milking Versus Delayed Cord Clamping in Infants 28 to 32 Weeks: A Randomized Trial.
Katheria A, Szychowski J, Carlo WA, Subramaniam A, Reister F, Essers J, Vora F, Martin C, Schmölzer GM, Law B, Dempsey E, O'Donoghue K, Kaempf J, Tomlinson M, Fulford K, Folsom B, Karam S, Morris R, Yanowitz T, Beck S, Clark E, DuPont T, Biniwale M, Ramanathan R, Bhat S, Hoffman M, Chouthai N, Bany-Mohammed F, Mydam J, Narendran V, Wertheimer F, Gollin Y, Vaucher Y, Arnell K, Varner M, Cutter G, Wilson N, Rich W; RRT, Finer N
Pediatrics 2023 Dec 1;152(6) doi: 10.1542/peds.2023-063113. PMID: 37941523
Interventions for patent ductus arteriosus (PDA) in preterm infants: an overview of Cochrane Systematic Reviews.
Mitra S, de Boode WP, Weisz DE, Shah PS
Cochrane Database Syst Rev 2023 Apr 11;4(4):CD013588. doi: 10.1002/14651858.CD013588.pub2. PMID: 37039501Free PMC Article
Association of Intraventricular Hemorrhage and Death With Tocolytic Exposure in Preterm Infants.
Pinto Cardoso G, Houivet E, Marchand-Martin L, Kayem G, Sentilhes L, Ancel PY, Lorthe E, Marret S; EPIPAGE-2 Working Group
JAMA Netw Open 2018 Sep 7;1(5):e182355. doi: 10.1001/jamanetworkopen.2018.2355. PMID: 30646165Free PMC Article
Early developmental intervention programmes provided post hospital discharge to prevent motor and cognitive impairment in preterm infants.
Spittle A, Orton J, Anderson PJ, Boyd R, Doyle LW
Cochrane Database Syst Rev 2015 Nov 24;2015(11):CD005495. doi: 10.1002/14651858.CD005495.pub4. PMID: 26597166Free PMC Article
Male/female differences in indomethacin effects in preterm infants.
Ohlsson A, Roberts RS, Schmidt B, Davis P, Moddeman D, Saigal S, Solimano A, Vincer M, Wright L; Trial Of Indomethacin Prophylaxis In Preterms Tipp Investigators
J Pediatr 2005 Dec;147(6):860-2. doi: 10.1016/j.jpeds.2005.07.032. PMID: 16356449

Prognosis

Retinopathy of prematurity screening: prevalence and risk factors of ophthalmic complications in non-treated preterm infants.
Strelnikov JI, Rao R, Majidi S, Lueder G, Lee A, Reynolds MM
Eye (Lond) 2024 Jun;38(8):1462-1470. Epub 2024 Jan 11 doi: 10.1038/s41433-023-02921-1. PMID: 38212403Free PMC Article
Interventions for patent ductus arteriosus (PDA) in preterm infants: an overview of Cochrane Systematic Reviews.
Mitra S, de Boode WP, Weisz DE, Shah PS
Cochrane Database Syst Rev 2023 Apr 11;4(4):CD013588. doi: 10.1002/14651858.CD013588.pub2. PMID: 37039501Free PMC Article
Neonatal Intraventricular Hemorrhage and Hospitalization in Childhood.
Kaur A, Luu TM, Shah PS, Ayoub A, Auger N
Pediatr Neurol 2020 Feb;103:35-42. Epub 2019 Oct 19 doi: 10.1016/j.pediatrneurol.2019.09.007. PMID: 31753542
Survival and morbidity of preterm children born at 22 through 34 weeks' gestation in France in 2011: results of the EPIPAGE-2 cohort study.
Ancel PY, Goffinet F; EPIPAGE-2 Writing Group, Kuhn P, Langer B, Matis J, Hernandorena X, Chabanier P, Joly-Pedespan L, Lecomte B, Vendittelli F, Dreyfus M, Guillois B, Burguet A, Sagot P, Sizun J, Beuchée A, Rouget F, Favreau A, Saliba E, Bednarek N, Morville P, Thiriez G, Marpeau L, Marret S, Kayem G, Durrmeyer X, Granier M, Baud O, Jarreau PH, Mitanchez D, Boileau P, Boulot P, Cambonie G, Daudé H, Bédu A, Mons F, Fresson J, Vieux R, Alberge C, Arnaud C, Vayssière C, Truffert P, Pierrat V, Subtil D, D'Ercole C, Gire C, Simeoni U, Bongain A, Sentilhes L, Rozé JC, Gondry J, Leke A, Deiber M, Claris O, Picaud JC, Ego A, Debillon T, Poulichet A, Coliné E, Favre A, Fléchelles O, Samperiz S, Ramful D, Branger B, Benhammou V, Foix-L'Hélias L, Marchand-Martin L, Kaminski M
JAMA Pediatr 2015 Mar;169(3):230-8. doi: 10.1001/jamapediatrics.2014.3351. PMID: 25621457
Intraventricular hemorrhage in the preterm infant.
Vohr B, Ment LR
Early Hum Dev 1996 Jan 5;44(1):1-16. doi: 10.1016/0378-3782(95)01692-9. PMID: 8821891

Clinical prediction guides

Reducing Severe Intraventricular Hemorrhage in Preterm Infants With Improved Care Bundle Adherence.
Kolnik SE, Upadhyay K, Wood TR, Juul SE, Valentine GC
Pediatrics 2023 Sep 1;152(3) doi: 10.1542/peds.2021-056104. PMID: 37609772
A predictive clinical model for moderate to severe intraventricular hemorrhage in very low birth weight infants.
Weinstein RM, Parkinson C, Everett AD, Graham EM, Vaidya D, Northington FJ
J Perinatol 2022 Oct;42(10):1374-1379. Epub 2022 Jul 2 doi: 10.1038/s41372-022-01435-0. PMID: 35780234
Antenatal prediction models for short- and medium-term outcomes in preterm infants.
Ushida T, Moriyama Y, Nakatochi M, Kobayashi Y, Imai K, Nakano-Kobayashi T, Nakamura N, Hayakawa M, Kajiyama H, Kotani T; Neonatal Research Network of Japan
Acta Obstet Gynecol Scand 2021 Jun;100(6):1089-1096. Epub 2021 Mar 18 doi: 10.1111/aogs.14136. PMID: 33656762
Low-Grade Intraventricular Hemorrhage and Neurodevelopmental Outcomes at 24-42 Months of Age.
Scott TE, Aboudi D, Kase JS
J Child Neurol 2020 Aug;35(9):578-584. Epub 2020 May 21 doi: 10.1177/0883073820922638. PMID: 32438867
Neonatal Intraventricular Hemorrhage and Hospitalization in Childhood.
Kaur A, Luu TM, Shah PS, Ayoub A, Auger N
Pediatr Neurol 2020 Feb;103:35-42. Epub 2019 Oct 19 doi: 10.1016/j.pediatrneurol.2019.09.007. PMID: 31753542

Recent systematic reviews

Interventions for patent ductus arteriosus (PDA) in preterm infants: an overview of Cochrane Systematic Reviews.
Mitra S, de Boode WP, Weisz DE, Shah PS
Cochrane Database Syst Rev 2023 Apr 11;4(4):CD013588. doi: 10.1002/14651858.CD013588.pub2. PMID: 37039501Free PMC Article
Postnatal phenobarbital for the prevention of intraventricular haemorrhage in preterm infants.
Romantsik O, Smit E, Odd DE, Bruschettini M
Cochrane Database Syst Rev 2023 Mar 16;3(3):CD001691. doi: 10.1002/14651858.CD001691.pub4. PMID: 36924438Free PMC Article
Adjuvant 17-hydroxyprogesterone caproate in women with history-indicated cerclage: A systematic review and meta-analysis.
Eke AC, Sheffield J, Graham EM
Acta Obstet Gynecol Scand 2019 Feb;98(2):139-153. Epub 2018 Nov 18 doi: 10.1111/aogs.13488. PMID: 30339274Free PMC Article
Early developmental intervention programmes provided post hospital discharge to prevent motor and cognitive impairment in preterm infants.
Spittle A, Orton J, Anderson PJ, Boyd R, Doyle LW
Cochrane Database Syst Rev 2015 Nov 24;2015(11):CD005495. doi: 10.1002/14651858.CD005495.pub4. PMID: 26597166Free PMC Article
Antenatal exposure to indomethacin increases the risk of severe intraventricular hemorrhage, necrotizing enterocolitis, and periventricular leukomalacia: a systematic review with metaanalysis.
Hammers AL, Sanchez-Ramos L, Kaunitz AM
Am J Obstet Gynecol 2015 Apr;212(4):505.e1-13. Epub 2014 Oct 30 doi: 10.1016/j.ajog.2014.10.1091. PMID: 25448524

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