U.S. flag

An official website of the United States government

Format

Send to:

Choose Destination

Reduced euglobulin clot lysis time

MedGen UID:
908297
Concept ID:
C4280701
Finding
HPO: HP:0040247

Definition

Abnormally decreased length of time required for an in vitro clot to dissolve in the absence of the normal plasmin inhibitors. This test is a clinical assay used to measure fibrinolysis. The euglobulin fraction of plasma is precipitated and used to form clot by addition of thrombin; after clot forms the rate of clot breakdown (fibrinolysis) can be monitored. [from HPO]

Term Hierarchy

CClinical test,  RResearch test,  OOMIM,  GGeneReviews,  VClinVar  
  • CROGVReduced euglobulin clot lysis time

Professional guidelines

PubMed

Dias JD, Butwick AJ, Hartmann J, Waters JH
Anaesthesia 2022 Jun;77(6):700-711. Epub 2022 Feb 22 doi: 10.1111/anae.15662. PMID: 35194779
Hvas CL, Hvas AM
Semin Thromb Hemost 2022 Apr;48(3):356-381. Epub 2021 Jul 14 doi: 10.1055/s-0041-1730346. PMID: 34261149
Kanji R, Kubica J, Navarese EP, Gorog DA
Eur J Clin Invest 2021 Apr;51(4):e13471. Epub 2020 Dec 16 doi: 10.1111/eci.13471. PMID: 33296082

Recent clinical studies

Etiology

Kanji R, Kubica J, Navarese EP, Gorog DA
Eur J Clin Invest 2021 Apr;51(4):e13471. Epub 2020 Dec 16 doi: 10.1111/eci.13471. PMID: 33296082
Sidelmann JJ, Gram JB, Rasmussen JJ, Kistorp C
Semin Thromb Hemost 2021 Feb;47(1):11-17. Epub 2020 Oct 5 doi: 10.1055/s-0040-1714398. PMID: 33017849
Undas A
Europace 2020 Feb 1;22(2):185-194. doi: 10.1093/europace/euz271. PMID: 31625555
Longstaff C
J Thromb Haemost 2018 Apr;16(4):652-662. Epub 2018 Feb 17 doi: 10.1111/jth.13957. PMID: 29363269Free PMC Article
Karasu A, Baglin TP, Luddington R, Baglin CA, van Hylckama Vlieg A
Br J Haematol 2016 Mar;172(6):947-53. Epub 2016 Jan 15 doi: 10.1111/bjh.13911. PMID: 26773756

Diagnosis

Coupland LA, Rabbolini DJ, Schoenecker JG, Crispin PJ, Miller JJ, Ghent T, Medcalf RL, Aneman AE
Crit Care 2023 Feb 10;27(1):55. doi: 10.1186/s13054-023-04329-5. PMID: 36765421Free PMC Article
Dias JD, Butwick AJ, Hartmann J, Waters JH
Anaesthesia 2022 Jun;77(6):700-711. Epub 2022 Feb 22 doi: 10.1111/anae.15662. PMID: 35194779
Miszta A, Ahmadzia HK, Luban NLC, Li S, Guo D, Holle LA, Berger JS, James AH, Gobburu JVS, van den Anker J, de Laat B, Wolberg AS
J Thromb Haemost 2021 Jan;19(1):221-232. Epub 2020 Dec 26 doi: 10.1111/jth.15114. PMID: 33001565Free PMC Article
Undas A
Europace 2020 Feb 1;22(2):185-194. doi: 10.1093/europace/euz271. PMID: 31625555
Longstaff C
J Thromb Haemost 2018 Apr;16(4):652-662. Epub 2018 Feb 17 doi: 10.1111/jth.13957. PMID: 29363269Free PMC Article

Therapy

Piróg M, Kacalska-Janssen O, Jach R, Wyroba J, Chrostowski B, Ząbczyk M, Natorska J
Reprod Sci 2022 Dec;29(12):3521-3531. Epub 2022 Jul 12 doi: 10.1007/s43032-022-01026-6. PMID: 35821349
Chen S, Chen D, Liu Y, Xu Y, Lin H, Cheng Y, Li J, Meng C, Liang M, Yuan C, Huang M
Br J Haematol 2022 Feb;196(4):1076-1085. Epub 2021 Nov 16 doi: 10.1111/bjh.17942. PMID: 34783361
Sidelmann JJ, Gram JB, Rasmussen JJ, Kistorp C
Semin Thromb Hemost 2021 Feb;47(1):11-17. Epub 2020 Oct 5 doi: 10.1055/s-0040-1714398. PMID: 33017849
Amadio P, Porro B, Sandrini L, Fiorelli S, Bonomi A, Cavalca V, Brambilla M, Camera M, Veglia F, Tremoli E, Barbieri SS
Sci Rep 2019 Jan 23;9(1):389. doi: 10.1038/s41598-018-37117-1. PMID: 30674980Free PMC Article
Staykov D, Schwab S
Curr Opin Crit Care 2013 Apr;19(2):92-100. doi: 10.1097/MCC.0b013e32835cae5e. PMID: 23337912

Prognosis

Mitrovic M, Sabljic N, Cvetkovic Z, Pantic N, Zivkovic Dakic A, Bukumiric Z, Libek V, Savic N, Milenkovic B, Virijevic M, Vucinic V, Milosevic I, Pravdic Z, Suvajdzic N, Fareed J, Antic D
Platelets 2021 Jul 4;32(5):690-696. Epub 2021 Feb 9 doi: 10.1080/09537104.2021.1881949. PMID: 33561381
Kanji R, Kubica J, Navarese EP, Gorog DA
Eur J Clin Invest 2021 Apr;51(4):e13471. Epub 2020 Dec 16 doi: 10.1111/eci.13471. PMID: 33296082
Gitto S, Romanelli RG, Cellai AP, Lami D, Vizzutti F, Abbate R, Margheri F, Fibbi G, Del Rosso M, Laffi G
Intern Emerg Med 2021 Mar;16(2):339-347. Epub 2020 May 22 doi: 10.1007/s11739-020-02375-3. PMID: 32445164
Undas A
Europace 2020 Feb 1;22(2):185-194. doi: 10.1093/europace/euz271. PMID: 31625555
Longstaff C
J Thromb Haemost 2018 Apr;16(4):652-662. Epub 2018 Feb 17 doi: 10.1111/jth.13957. PMID: 29363269Free PMC Article

Clinical prediction guides

Kanji R, Kubica J, Navarese EP, Gorog DA
Eur J Clin Invest 2021 Apr;51(4):e13471. Epub 2020 Dec 16 doi: 10.1111/eci.13471. PMID: 33296082
Sidelmann JJ, Gram JB, Rasmussen JJ, Kistorp C
Semin Thromb Hemost 2021 Feb;47(1):11-17. Epub 2020 Oct 5 doi: 10.1055/s-0040-1714398. PMID: 33017849
Undas A
Europace 2020 Feb 1;22(2):185-194. doi: 10.1093/europace/euz271. PMID: 31625555
Longstaff C
J Thromb Haemost 2018 Apr;16(4):652-662. Epub 2018 Feb 17 doi: 10.1111/jth.13957. PMID: 29363269Free PMC Article
Karasu A, Baglin TP, Luddington R, Baglin CA, van Hylckama Vlieg A
Br J Haematol 2016 Mar;172(6):947-53. Epub 2016 Jan 15 doi: 10.1111/bjh.13911. PMID: 26773756

Recent systematic reviews

Supplemental Content

Table of contents

    Clinical resources

    Practice guidelines

    • PubMed
      See practice and clinical guidelines in PubMed. The search results may include broader topics and may not capture all published guidelines. See the FAQ for details.
    • Bookshelf
      See practice and clinical guidelines in NCBI Bookshelf. The search results may include broader topics and may not capture all published guidelines. See the FAQ for details.

    Consumer resources

    Recent activity

    Your browsing activity is empty.

    Activity recording is turned off.

    Turn recording back on

    See more...