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t(6;11)

MedGen UID:
925469
Concept ID:
C4287937
Cell or Molecular Dysfunction

Definition

A cytogenetic abnormality that involves a translocation between chromosomes 6 and 11. [from NCI]

Term Hierarchy

CClinical test,  RResearch test,  OOMIM,  GGeneReviews,  VClinVar  
  • CROGVt(6;11)

Professional guidelines

PubMed

Brunet BCFK, Shen J, Cai L, Xie J, Cui Y, Liu J, Wu W
Reprod Biomed Online 2018 Sep;37(3):375-382. Epub 2018 Jul 17 doi: 10.1016/j.rbmo.2018.07.001. PMID: 30314889
McDonnell KK, Strayer SM, Sercy E, Campbell C, Friedman DB, Cartmell KB, Eberth JM
Health Expect 2018 Aug;21(4):796-804. Epub 2018 Feb 23 doi: 10.1111/hex.12675. PMID: 29473696Free PMC Article
Delahunt B, Srigley JR, Montironi R, Egevad L
Urology 2014 May;83(5):969-74. Epub 2014 Mar 22 doi: 10.1016/j.urology.2014.02.004. PMID: 24661331

Recent clinical studies

Etiology

Wei S, Testa JR, Argani P
Histol Histopathol 2022 Apr;37(4):311-321. Epub 2022 Feb 2 doi: 10.14670/HH-18-426. PMID: 35107169
Argani P
Genes Chromosomes Cancer 2022 May;61(5):219-227. Epub 2021 Nov 3 doi: 10.1002/gcc.23007. PMID: 34704642
Pederzoli F, Bandini M, Marandino L, Ali SM, Madison R, Chung J, Ross JS, Necchi A
Nat Rev Urol 2020 Nov;17(11):613-625. Epub 2020 Oct 12 doi: 10.1038/s41585-020-00379-4. PMID: 33046892
Bill M, Mrózek K, Kohlschmidt J, Eisfeld AK, Walker CJ, Nicolet D, Papaioannou D, Blachly JS, Orwick S, Carroll AJ, Kolitz JE, Powell BL, Stone RM, de la Chapelle A, Byrd JC, Bloomfield CD
Proc Natl Acad Sci U S A 2020 Oct 20;117(42):26340-26346. Epub 2020 Oct 5 doi: 10.1073/pnas.2014732117. PMID: 33020282Free PMC Article
Grimwade D, Hills RK, Moorman AV, Walker H, Chatters S, Goldstone AH, Wheatley K, Harrison CJ, Burnett AK; National Cancer Research Institute Adult Leukaemia Working Group
Blood 2010 Jul 22;116(3):354-65. Epub 2010 Apr 12 doi: 10.1182/blood-2009-11-254441. PMID: 20385793

Diagnosis

Attarbaschi A, Möricke A, Harrison CJ, Mann G, Baruchel A, De Moerloose B, Conter V, Devidas M, Elitzur S, Escherich G, Hunger SP, Horibe K, Manabe A, Loh ML, Pieters R, Schmiegelow K, Silverman LB, Stary J, Vora A, Pui CH, Schrappe M, Zimmermann M; Ponte-di-Legno Childhood Acute Lymphoblastic Leukemia Working Group
J Clin Oncol 2023 Mar 1;41(7):1404-1422. Epub 2022 Oct 18 doi: 10.1200/JCO.22.01297. PMID: 36256911Free PMC Article
Jansi Prema KS, Devanathan KS, Kurien AA
Indian J Pathol Microbiol 2017 Oct-Dec;60(4):574-576. doi: 10.4103/IJPM.IJPM_751_16. PMID: 29323078
Kryvenko ON, Jorda M, Argani P, Epstein JI
Arch Pathol Lab Med 2014 Nov;138(11):1531-41. doi: 10.5858/arpa.2013-0653-RA. PMID: 25357116Free PMC Article
Grimwade D, Hills RK, Moorman AV, Walker H, Chatters S, Goldstone AH, Wheatley K, Harrison CJ, Burnett AK; National Cancer Research Institute Adult Leukaemia Working Group
Blood 2010 Jul 22;116(3):354-65. Epub 2010 Apr 12 doi: 10.1182/blood-2009-11-254441. PMID: 20385793
Argani P, Ladanyi M
Clin Lab Med 2005 Jun;25(2):363-78. doi: 10.1016/j.cll.2005.01.008. PMID: 15848741

Therapy

Kawashiri A, Nakagawa SI, Ishiguro C, Mochizuki K, Maeda Y, Kurokawa T
J Clin Exp Hematop 2022;62(3):175-180. doi: 10.3960/jslrt.22014. PMID: 36171097Free PMC Article
Prachi, Aiyer HM
Indian J Pathol Microbiol 2021 Jul-Sep;64(3):553-555. doi: 10.4103/IJPM.IJPM_365_20. PMID: 34341271
Murrock CJ, Graor CH
J Aging Phys Act 2014 Jul;22(3):380-5. Epub 2013 Aug 12 doi: 10.1123/japa.2013-0003. PMID: 23945631
Grimwade D, Hills RK, Moorman AV, Walker H, Chatters S, Goldstone AH, Wheatley K, Harrison CJ, Burnett AK; National Cancer Research Institute Adult Leukaemia Working Group
Blood 2010 Jul 22;116(3):354-65. Epub 2010 Apr 12 doi: 10.1182/blood-2009-11-254441. PMID: 20385793
Zhang L, Rothman N, Li G, Guo W, Yang W, Hubbard AE, Hayes RB, Yin S, Lu W, Smith MT
Environ Mol Mutagen 2007 Jul;48(6):467-74. doi: 10.1002/em.20306. PMID: 17584886

Prognosis

Attarbaschi A, Möricke A, Harrison CJ, Mann G, Baruchel A, De Moerloose B, Conter V, Devidas M, Elitzur S, Escherich G, Hunger SP, Horibe K, Manabe A, Loh ML, Pieters R, Schmiegelow K, Silverman LB, Stary J, Vora A, Pui CH, Schrappe M, Zimmermann M; Ponte-di-Legno Childhood Acute Lymphoblastic Leukemia Working Group
J Clin Oncol 2023 Mar 1;41(7):1404-1422. Epub 2022 Oct 18 doi: 10.1200/JCO.22.01297. PMID: 36256911Free PMC Article
Bill M, Mrózek K, Kohlschmidt J, Eisfeld AK, Walker CJ, Nicolet D, Papaioannou D, Blachly JS, Orwick S, Carroll AJ, Kolitz JE, Powell BL, Stone RM, de la Chapelle A, Byrd JC, Bloomfield CD
Proc Natl Acad Sci U S A 2020 Oct 20;117(42):26340-26346. Epub 2020 Oct 5 doi: 10.1073/pnas.2014732117. PMID: 33020282Free PMC Article
Gandhi JS, Malik F, Amin MB, Argani P, Bahrami A
Histol Histopathol 2020 Feb;35(2):125-136. Epub 2019 Sep 6 doi: 10.14670/HH-18-159. PMID: 31489603
Delahunt B, Srigley JR, Montironi R, Egevad L
Urology 2014 May;83(5):969-74. Epub 2014 Mar 22 doi: 10.1016/j.urology.2014.02.004. PMID: 24661331
Grimwade D, Hills RK, Moorman AV, Walker H, Chatters S, Goldstone AH, Wheatley K, Harrison CJ, Burnett AK; National Cancer Research Institute Adult Leukaemia Working Group
Blood 2010 Jul 22;116(3):354-65. Epub 2010 Apr 12 doi: 10.1182/blood-2009-11-254441. PMID: 20385793

Clinical prediction guides

Zhang Y, Zhan P, Wang Y, Tian W, Yang X, Wang X
Medicine (Baltimore) 2023 Jul 7;102(27):e34318. doi: 10.1097/MD.0000000000034318. PMID: 37417617Free PMC Article
Attarbaschi A, Möricke A, Harrison CJ, Mann G, Baruchel A, De Moerloose B, Conter V, Devidas M, Elitzur S, Escherich G, Hunger SP, Horibe K, Manabe A, Loh ML, Pieters R, Schmiegelow K, Silverman LB, Stary J, Vora A, Pui CH, Schrappe M, Zimmermann M; Ponte-di-Legno Childhood Acute Lymphoblastic Leukemia Working Group
J Clin Oncol 2023 Mar 1;41(7):1404-1422. Epub 2022 Oct 18 doi: 10.1200/JCO.22.01297. PMID: 36256911Free PMC Article
Kuroda N, Yorita K, Sasaki N, Ishihara A, Matsuura K, Daa T, Mori S, Sasaki A, Mikami S, Shigematsu K, Nagashima Y
Pol J Pathol 2017;68(1):66-72. doi: 10.5114/pjp.2017.67617. PMID: 28547982
Kuroda N, Tanaka A, Sasaki N, Ishihara A, Matsuura K, Moriyama M, Nagashima Y, Inoue K, Petersson F, Martignoni G, Michal M, Hes O
Histol Histopathol 2013 Jun;28(6):685-90. Epub 2013 Feb 21 doi: 10.14670/HH-28.685. PMID: 23426439
Grimwade D, Hills RK, Moorman AV, Walker H, Chatters S, Goldstone AH, Wheatley K, Harrison CJ, Burnett AK; National Cancer Research Institute Adult Leukaemia Working Group
Blood 2010 Jul 22;116(3):354-65. Epub 2010 Apr 12 doi: 10.1182/blood-2009-11-254441. PMID: 20385793

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