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t(14;18)

MedGen UID:
925479
Concept ID:
C4287947
Cell or Molecular Dysfunction

Definition

A cytogenetic abnormality that involves a translocation between chromosomes 14 and 18. [from NCI]

Term Hierarchy

CClinical test,  RResearch test,  OOMIM,  GGeneReviews,  VClinVar  
  • CROGVt(14;18)

Professional guidelines

PubMed

Jacobsen E
Am J Hematol 2022 Dec;97(12):1638-1651. Epub 2022 Oct 18 doi: 10.1002/ajh.26737. PMID: 36255040
Mozas P, Sorigué M, López-Guillermo A
Med Clin (Barc) 2021 Nov 12;157(9):440-448. Epub 2021 Jun 29 doi: 10.1016/j.medcli.2021.03.041. PMID: 34210513
Freedman A, Jacobsen E
Am J Hematol 2020 Mar;95(3):316-327. Epub 2019 Dec 22 doi: 10.1002/ajh.25696. PMID: 31814159

Recent clinical studies

Etiology

Salaverria I, Weigert O, Quintanilla-Martinez L
Blood Adv 2023 Sep 26;7(18):5258-5271. doi: 10.1182/bloodadvances.2022009456. PMID: 37561599Free PMC Article
Jacobsen E
Am J Hematol 2022 Dec;97(12):1638-1651. Epub 2022 Oct 18 doi: 10.1002/ajh.26737. PMID: 36255040
Freedman A, Jacobsen E
Am J Hematol 2020 Mar;95(3):316-327. Epub 2019 Dec 22 doi: 10.1002/ajh.25696. PMID: 31814159
Carbone A, Roulland S, Gloghini A, Younes A, von Keudell G, López-Guillermo A, Fitzgibbon J
Nat Rev Dis Primers 2019 Dec 12;5(1):83. doi: 10.1038/s41572-019-0132-x. PMID: 31831752
Vitolo U, Ferreri AJ, Montoto S
Crit Rev Oncol Hematol 2008 Jun;66(3):248-61. Epub 2008 Mar 21 doi: 10.1016/j.critrevonc.2008.01.014. PMID: 18359244

Diagnosis

Laurent C, Cook JR, Yoshino T, Quintanilla-Martinez L, Jaffe ES
Virchows Arch 2023 Jan;482(1):149-162. Epub 2022 Nov 17 doi: 10.1007/s00428-022-03432-2. PMID: 36394631Free PMC Article
Jacobsen E
Am J Hematol 2022 Dec;97(12):1638-1651. Epub 2022 Oct 18 doi: 10.1002/ajh.26737. PMID: 36255040
Mozas P, Sorigué M, López-Guillermo A
Med Clin (Barc) 2021 Nov 12;157(9):440-448. Epub 2021 Jun 29 doi: 10.1016/j.medcli.2021.03.041. PMID: 34210513
Freedman A, Jacobsen E
Am J Hematol 2020 Mar;95(3):316-327. Epub 2019 Dec 22 doi: 10.1002/ajh.25696. PMID: 31814159
Carbone A, Roulland S, Gloghini A, Younes A, von Keudell G, López-Guillermo A, Fitzgibbon J
Nat Rev Dis Primers 2019 Dec 12;5(1):83. doi: 10.1038/s41572-019-0132-x. PMID: 31831752

Therapy

Gordon MJ, Smith MR, Nastoupil LJ
Blood Rev 2023 Jan;57:100992. Epub 2022 Jul 23 doi: 10.1016/j.blre.2022.100992. PMID: 35908982
Jacobsen E
Am J Hematol 2022 Dec;97(12):1638-1651. Epub 2022 Oct 18 doi: 10.1002/ajh.26737. PMID: 36255040
Hryhorczuk D, Dardynskaia I, Hirt C, Dardynskiy O, Turner W, Ruestow P, Bartell S, Steenland K, Zvinchuk O, Baccarelli AA
J Occup Environ Med 2022 Apr 1;64(4):331-339. Epub 2021 Nov 3 doi: 10.1097/JOM.0000000000002427. PMID: 34740219
Freedman A, Jacobsen E
Am J Hematol 2020 Mar;95(3):316-327. Epub 2019 Dec 22 doi: 10.1002/ajh.25696. PMID: 31814159
Carbone A, Roulland S, Gloghini A, Younes A, von Keudell G, López-Guillermo A, Fitzgibbon J
Nat Rev Dis Primers 2019 Dec 12;5(1):83. doi: 10.1038/s41572-019-0132-x. PMID: 31831752

Prognosis

Jacobsen E
Am J Hematol 2022 Dec;97(12):1638-1651. Epub 2022 Oct 18 doi: 10.1002/ajh.26737. PMID: 36255040
Mozas P, Sorigué M, López-Guillermo A
Med Clin (Barc) 2021 Nov 12;157(9):440-448. Epub 2021 Jun 29 doi: 10.1016/j.medcli.2021.03.041. PMID: 34210513
Nann D, Ramis-Zaldivar JE, Müller I, Gonzalez-Farre B, Schmidt J, Egan C, Salmeron-Villalobos J, Clot G, Mattern S, Otto F, Mankel B, Colomer D, Balagué O, Szablewski V, Lome-Maldonado C, Leoncini L, Dojcinov S, Chott A, Copie-Bergman C, Bonzheim I, Fend F, Jaffe ES, Campo E, Salaverria I, Quintanilla-Martinez L
Blood Adv 2020 Nov 24;4(22):5652-5665. doi: 10.1182/bloodadvances.2020002944. PMID: 33211828Free PMC Article
Freedman A, Jacobsen E
Am J Hematol 2020 Mar;95(3):316-327. Epub 2019 Dec 22 doi: 10.1002/ajh.25696. PMID: 31814159
Lackraj T, Goswami R, Kridel R
Best Pract Res Clin Haematol 2018 Mar;31(1):2-14. Epub 2017 Nov 1 doi: 10.1016/j.beha.2017.10.006. PMID: 29452662

Clinical prediction guides

Panjan M, Boltezar L, Novakovic S, Kokovic I, Jezersek Novakovic B
Radiol Oncol 2023 Dec 1;57(4):487-492. Epub 2023 Jul 13 doi: 10.2478/raon-2023-0030. PMID: 37439703Free PMC Article
Jacobsen E
Am J Hematol 2022 Dec;97(12):1638-1651. Epub 2022 Oct 18 doi: 10.1002/ajh.26737. PMID: 36255040
Freedman A, Jacobsen E
Am J Hematol 2020 Mar;95(3):316-327. Epub 2019 Dec 22 doi: 10.1002/ajh.25696. PMID: 31814159
Aukema SM, Siebert R, Schuuring E, van Imhoff GW, Kluin-Nelemans HC, Boerma EJ, Kluin PM
Blood 2011 Feb 24;117(8):2319-31. Epub 2010 Nov 30 doi: 10.1182/blood-2010-09-297879. PMID: 21119107
Vitolo U, Ferreri AJ, Montoto S
Crit Rev Oncol Hematol 2008 Jun;66(3):248-61. Epub 2008 Mar 21 doi: 10.1016/j.critrevonc.2008.01.014. PMID: 18359244

Recent systematic reviews

Enemark MH, Hemmingsen JK, Jensen ML, Kridel R, Ludvigsen M
Int J Mol Sci 2024 Oct 17;25(20) doi: 10.3390/ijms252011179. PMID: 39456961Free PMC Article
Zedan HT, Ali FH, Zayed H
Chromosoma 2022 Sep;131(3):127-146. Epub 2022 Jul 30 doi: 10.1007/s00412-022-00775-2. PMID: 35907041Free PMC Article

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