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Membranous Nephropathy - Secondary

MedGen UID:
926295
•Concept ID:
C4288763
•
Disease or Syndrome
Synonym: Secondary Membranous Glomerulopathy

Definition

Membranous nephropathy due to another medical condition. [from NCI]

Term Hierarchy

CClinical test,  RResearch test,  OOMIM,  GGeneReviews,  VClinVar  
  • CROGVMembranous Nephropathy - Secondary

Professional guidelines

PubMed

The value of PLA2R antigen and IgG subclass staining relative to anti-PLA2R seropositivity in the differential diagnosis of membranous nephropathy.
Bajcsi D, Bitó L, Turkevi-Nagy S, Nyári T, Kemény É, Légrády P, Ábrahám G, Iványi B
BMC Nephrol 2023 Aug 7;24(1):230. doi: 10.1186/s12882-023-03273-4. PMID: 37550626Free PMC Article
Can use of the serum anti-PLA2R antibody negate the need for a renal biopsy in primary membranous nephropathy?
Ragy O, Rautemaa V, Smith A, Brenchley P, Kanigicherla D, Hamilton P
PLoS One 2023;18(2):e0281726. Epub 2023 Feb 24 doi: 10.1371/journal.pone.0281726. PMID: 36827283Free PMC Article
Role of light and immunofluorescence microscopy to differentiate primary and secondary membranous nephropathy.
Basu K, Sengupta M, Mukherjee S, Karmakar S, Roychowdhury A, Bandopadhyay M
Indian J Pathol Microbiol 2022 Oct-Dec;65(4):821-827. doi: 10.4103/ijpm.ijpm_22_21. PMID: 36308187

Recent clinical studies

Etiology

How to Choose the Right Treatment for Membranous Nephropathy.
Peritore L, Labbozzetta V, Maressa V, Casuscelli C, Conti G, Gembillo G, Santoro D
Medicina (Kaunas) 2023 Nov 14;59(11) doi: 10.3390/medicina59111997. PMID: 38004046Free PMC Article
EditorialAssignment.
Xu Y, Yang Q, Fu C, Han E, Gao Y
BMJ Open 2023 Jan 18;13(1):e064220. doi: 10.1136/bmjopen-2022-064220. PMID: 36657752Free PMC Article
Primary membranous nephropathy: an endless story.
Claudio P
J Nephrol 2023 Mar;36(2):563-574. Epub 2022 Oct 17 doi: 10.1007/s40620-022-01461-3. PMID: 36251213
Exostosin 1/Exostosin 2-Associated Membranous Nephropathy.
Sethi S, Madden BJ, Debiec H, Charlesworth MC, Gross L, Ravindran A, Hummel AM, Specks U, Fervenza FC, Ronco P
J Am Soc Nephrol 2019 Jun;30(6):1123-1136. Epub 2019 May 6 doi: 10.1681/ASN.2018080852. PMID: 31061139Free PMC Article
Primary Membranous Nephropathy.
Couser WG
Clin J Am Soc Nephrol 2017 Jun 7;12(6):983-997. Epub 2017 May 26 doi: 10.2215/CJN.11761116. PMID: 28550082Free PMC Article

Diagnosis

Membranous Nephropathy: Core Curriculum 2021.
Alsharhan L, Beck LH Jr
Am J Kidney Dis 2021 Mar;77(3):440-453. Epub 2021 Jan 21 doi: 10.1053/j.ajkd.2020.10.009. PMID: 33487481
New 'Antigens' in Membranous Nephropathy.
Sethi S
J Am Soc Nephrol 2021 Feb;32(2):268-278. Epub 2020 Dec 30 doi: 10.1681/ASN.2020071082. PMID: 33380523Free PMC Article
Primary Membranous Nephropathy.
Couser WG
Clin J Am Soc Nephrol 2017 Jun 7;12(6):983-997. Epub 2017 May 26 doi: 10.2215/CJN.11761116. PMID: 28550082Free PMC Article
Diagnosis and Management of Nephrotic Syndrome in Adults.
Kodner C
Am Fam Physician 2016 Mar 15;93(6):479-85. PMID: 26977832
Nephrotic syndrome in adults: diagnosis and management.
Kodner C
Am Fam Physician 2009 Nov 15;80(10):1129-34. PMID: 19904897

Therapy

EditorialAssignment.
Xu Y, Yang Q, Fu C, Han E, Gao Y
BMJ Open 2023 Jan 18;13(1):e064220. doi: 10.1136/bmjopen-2022-064220. PMID: 36657752Free PMC Article
Membranous Nephropathy: Core Curriculum 2021.
Alsharhan L, Beck LH Jr
Am J Kidney Dis 2021 Mar;77(3):440-453. Epub 2021 Jan 21 doi: 10.1053/j.ajkd.2020.10.009. PMID: 33487481
Primary Membranous Nephropathy.
Couser WG
Clin J Am Soc Nephrol 2017 Jun 7;12(6):983-997. Epub 2017 May 26 doi: 10.2215/CJN.11761116. PMID: 28550082Free PMC Article
Diagnosis and Management of Nephrotic Syndrome in Adults.
Kodner C
Am Fam Physician 2016 Mar 15;93(6):479-85. PMID: 26977832
Nephrotic syndrome in childhood.
Eddy AA, Symons JM
Lancet 2003 Aug 23;362(9384):629-39. doi: 10.1016/S0140-6736(03)14184-0. PMID: 12944064

Prognosis

Membranous Nephropathy: Core Curriculum 2021.
Alsharhan L, Beck LH Jr
Am J Kidney Dis 2021 Mar;77(3):440-453. Epub 2021 Jan 21 doi: 10.1053/j.ajkd.2020.10.009. PMID: 33487481
Glomerulonephritis Histopathological Pattern Change.
AlYousef A, AlSahow A, AlHelal B, Alqallaf A, Abdallah E, Abdellatif M, Nawar H, Elmahalawy R
BMC Nephrol 2020 May 18;21(1):186. doi: 10.1186/s12882-020-01836-3. PMID: 32423387Free PMC Article
Exostosin 1/Exostosin 2-Associated Membranous Nephropathy.
Sethi S, Madden BJ, Debiec H, Charlesworth MC, Gross L, Ravindran A, Hummel AM, Specks U, Fervenza FC, Ronco P
J Am Soc Nephrol 2019 Jun;30(6):1123-1136. Epub 2019 May 6 doi: 10.1681/ASN.2018080852. PMID: 31061139Free PMC Article
Diagnosis and Management of Nephrotic Syndrome in Adults.
Kodner C
Am Fam Physician 2016 Mar 15;93(6):479-85. PMID: 26977832
Nephrotic syndrome in childhood.
Eddy AA, Symons JM
Lancet 2003 Aug 23;362(9384):629-39. doi: 10.1016/S0140-6736(03)14184-0. PMID: 12944064

Clinical prediction guides

Clinical covariates influencing clinical outcomes in primary membranous nephropathy.
Westermann L, Rottmann FA, Hug MJ, Staudacher DL, Wobser R, Arnold F, Welte T
BMC Nephrol 2023 Aug 10;24(1):235. doi: 10.1186/s12882-023-03288-x. PMID: 37563703Free PMC Article
Autoantibodies in the Diagnosis, Monitoring, and Treatment of Membranous Nephropathy.
Tesar V, Hruskova Z
Front Immunol 2021;12:593288. Epub 2021 Mar 22 doi: 10.3389/fimmu.2021.593288. PMID: 33828546Free PMC Article
Membranous Nephropathy: Core Curriculum 2021.
Alsharhan L, Beck LH Jr
Am J Kidney Dis 2021 Mar;77(3):440-453. Epub 2021 Jan 21 doi: 10.1053/j.ajkd.2020.10.009. PMID: 33487481
Glomerulonephritis Histopathological Pattern Change.
AlYousef A, AlSahow A, AlHelal B, Alqallaf A, Abdallah E, Abdellatif M, Nawar H, Elmahalawy R
BMC Nephrol 2020 May 18;21(1):186. doi: 10.1186/s12882-020-01836-3. PMID: 32423387Free PMC Article
Membranous nephropathy: not just a disease for adults.
Ayalon R, Beck LH Jr
Pediatr Nephrol 2015 Jan;30(1):31-9. Epub 2013 Dec 29 doi: 10.1007/s00467-013-2717-z. PMID: 24375012Free PMC Article

Recent systematic reviews

Prevalence and distribution of primary glomerular diseases in Africa: a systematic review and meta-analysis of observational studies.
Ekrikpo UE, Obiagwu PN, Udo AI, Chukwuonye II, Noubiap JJ, Okpechi-Samuel US, Udoudo UN, Tannor EK, Ngoka SC, Mbah IO, Bello AK, Okpechi IG
Pan Afr Med J 2023;45:153. Epub 2023 Aug 9 doi: 10.11604/pamj.2023.45.153.40741. PMID: 37869232Free PMC Article
Cyclophosphamide induced early remission and was superior to rituximab in idiopathic membranous nephropathy patients with high anti-PLA2R antibody levels.
Xue C, Wang J, Pan J, Liang C, Zhou C, Wu J, Song S, Cui L, Zhang L, Liu Y, Dai B
BMC Nephrol 2023 Sep 22;24(1):280. doi: 10.1186/s12882-023-03307-x. PMID: 37740193Free PMC Article
Immunosuppression therapy for idiopathic membranous nephropathy: systematic review with network meta-analysis.
Bose B, Chung EYM, Hong R, Strippoli GFM, Johnson DW, Yang WL, Badve SV, Palmer SC
J Nephrol 2022 May;35(4):1159-1170. Epub 2022 Feb 23 doi: 10.1007/s40620-022-01268-2. PMID: 35199314Free PMC Article
Induction therapy for membranous lupus nephritis: a systematic review and network meta-analysis.
Tang KT, Tseng CH, Hsieh TY, Chen DY
Int J Rheum Dis 2018 Jun;21(6):1163-1172. doi: 10.1111/1756-185X.13321. PMID: 29879319
Rituximab therapy for membranous nephropathy: a systematic review.
Bomback AS, Derebail VK, McGregor JG, Kshirsagar AV, Falk RJ, Nachman PH
Clin J Am Soc Nephrol 2009 Apr;4(4):734-44. Epub 2009 Mar 11 doi: 10.2215/CJN.05231008. PMID: 19279120Free PMC Article

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