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Nasopharyngeal carcinoma, susceptibility to

MedGen UID:
937826
•Concept ID:
C4313859
•
Finding

Term Hierarchy

CClinical test,  RResearch test,  OOMIM,  GGeneReviews,  VClinVar  
  • CROGVNasopharyngeal carcinoma, susceptibility to

Professional guidelines

PubMed

Contribution of Matrix Metallopeptidase-1 Genotypes, Smoking, Alcohol Drinking and Areca Chewing to Nasopharyngeal Carcinoma Susceptibility.
Tsai CW, Chang WS, Gong CL, Shih LC, Chen LY, Lin EY, Li HT, Yen ST, Wu CN, Bau DT
Anticancer Res 2016 Jul;36(7):3335-40. PMID: 27354591

Recent clinical studies

Etiology

Whole-Exome Sequencing Study of Familial Nasopharyngeal Carcinoma and Its Implication for Identifying High-Risk Individuals.
Wang TM, He YQ, Xue WQ, Zhang JB, Xia YF, Deng CM, Zhang WL, Xiao RW, Liao Y, Yang DW, Zhou T, Li DH, Luo LT, Tong XT, Wu YX, Chen XY, Li XZ, Zhang PF, Zheng XH, Zhang SD, Hu YZ, Wang F, Wu ZY, Zheng MQ, Huang JW, Jia YJ, Yuan LL, You R, Zhou GQ, Lu LX, Liu YY, Chen MY, Feng L, Dai W, Ren ZF, Mai HQ, Sun Y, Ma J, Zheng W, Lung ML, Jia WH
J Natl Cancer Inst 2022 Dec 8;114(12):1689-1697. doi: 10.1093/jnci/djac177. PMID: 36066420
A Phase II Randomized Clinical Trial and Mechanistic Studies Using Improved Probiotics to Prevent Oral Mucositis Induced by Concurrent Radiotherapy and Chemotherapy in Nasopharyngeal Carcinoma.
Xia C, Jiang C, Li W, Wei J, Hong H, Li J, Feng L, Wei H, Xin H, Chen T
Front Immunol 2021;12:618150. Epub 2021 Mar 24 doi: 10.3389/fimmu.2021.618150. PMID: 33841399Free PMC Article
Genome-Wide Meta-Analysis Identifies Three Novel Susceptibility Loci and Reveals Ethnic Heterogeneity of Genetic Susceptibility for IgA Nephropathy.
Li M, Wang L, Shi DC, Foo JN, Zhong Z, Khor CC, Lanzani C, Citterio L, Salvi E, Yin PR, Bei JX, Wang L, Liao YH, Chen J, Chen QK, Xu G, Jiang GR, Wan JX, Chen MH, Chen N, Zhang H, Zeng YX, Liu ZH, Liu JJ, Yu XQ
J Am Soc Nephrol 2020 Dec;31(12):2949-2963. Epub 2020 Sep 10 doi: 10.1681/ASN.2019080799. PMID: 32912934Free PMC Article
The HLA-DRB1 allele polymorphisms and nasopharyngeal carcinoma.
Yang H, Yu K, Zhang R, Li J, Wei X, Zhang Y, Zhang C, Xiao F, Zhao D, Lin X, Wu H, Yang X
Tumour Biol 2016 Jun;37(6):7119-28. Epub 2016 Apr 8 doi: 10.1007/s13277-016-5051-9. PMID: 27059731
Nasopharyngeal Cancer: Molecular Landscape.
Bruce JP, Yip K, Bratman SV, Ito E, Liu FF
J Clin Oncol 2015 Oct 10;33(29):3346-55. Epub 2015 Sep 8 doi: 10.1200/JCO.2015.60.7846. PMID: 26351340

Diagnosis

A Phase II Randomized Clinical Trial and Mechanistic Studies Using Improved Probiotics to Prevent Oral Mucositis Induced by Concurrent Radiotherapy and Chemotherapy in Nasopharyngeal Carcinoma.
Xia C, Jiang C, Li W, Wei J, Hong H, Li J, Feng L, Wei H, Xin H, Chen T
Front Immunol 2021;12:618150. Epub 2021 Mar 24 doi: 10.3389/fimmu.2021.618150. PMID: 33841399Free PMC Article
PP2A and tumor radiotherapy.
Lei X, Ma N, Du L, Liang Y, Zhang P, Han Y, Qu B
Hereditas 2020 Aug 26;157(1):36. doi: 10.1186/s41065-020-00149-7. PMID: 32847617Free PMC Article
Radio-Susceptibility of Nasopharyngeal Carcinoma: Focus on Epstein- Barr Virus, MicroRNAs, Long Non-Coding RNAs and Circular RNAs.
Lei F, Lei T, Huang Y, Yang M, Liao M, Huang W
Curr Mol Pharmacol 2020;13(3):192-205. doi: 10.2174/1874467213666191227104646. PMID: 31880267
Nasopharyngeal Cancer: Molecular Landscape.
Bruce JP, Yip K, Bratman SV, Ito E, Liu FF
J Clin Oncol 2015 Oct 10;33(29):3346-55. Epub 2015 Sep 8 doi: 10.1200/JCO.2015.60.7846. PMID: 26351340
Nasopharyngeal carcinoma.
Brennan B
Orphanet J Rare Dis 2006 Jun 26;1:23. doi: 10.1186/1750-1172-1-23. PMID: 16800883Free PMC Article

Therapy

A Phase II Randomized Clinical Trial and Mechanistic Studies Using Improved Probiotics to Prevent Oral Mucositis Induced by Concurrent Radiotherapy and Chemotherapy in Nasopharyngeal Carcinoma.
Xia C, Jiang C, Li W, Wei J, Hong H, Li J, Feng L, Wei H, Xin H, Chen T
Front Immunol 2021;12:618150. Epub 2021 Mar 24 doi: 10.3389/fimmu.2021.618150. PMID: 33841399Free PMC Article
Microbial etiology, susceptibility profile of postradiation nasopharyngeal necrosis patients with nasopharyngeal carcinoma.
Wang L, Yang J, Peng SY, Li GQ, Tu ZW
Cancer Radiother 2020 Apr;24(2):93-98. Epub 2020 Feb 11 doi: 10.1016/j.canrad.2019.09.008. PMID: 32057645
Nasopharyngeal carcinoma: understanding its molecular biology at a fine scale.
Paul P, Deka H, Malakar AK, Halder B, Chakraborty S
Eur J Cancer Prev 2018 Jan;27(1):33-41. doi: 10.1097/CEJ.0000000000000314. PMID: 27748661
Quantitative assessment of the association between interleukin-10 promoter gene polymorphisms and nasopharyngeal carcinoma susceptibility.
Huang H, Wu Y, Liao D, Zhang H
Minerva Med 2016 Apr;107(2):92-100. Epub 2016 Feb 3 PMID: 26842763
Nasopharyngeal carcinoma.
Brennan B
Orphanet J Rare Dis 2006 Jun 26;1:23. doi: 10.1186/1750-1172-1-23. PMID: 16800883Free PMC Article

Prognosis

Correlation between COX-2 gene polymorphism and susceptibility to nasopharyngeal carcinoma.
Sun N, Wang XQ
Eur Rev Med Pharmacol Sci 2019 Jul;23(13):5770-5778. doi: 10.26355/eurrev_201907_18315. PMID: 31298328
A pooled analysis of the IL-10-1082 A/G polymorphism and the nasopharyngeal carcinoma susceptibility.
Ma L, Li S, Lu Y, Zhang X, Zhao J, Qin X
Eur Arch Otorhinolaryngol 2016 Apr;273(4):819-25. Epub 2014 Dec 31 doi: 10.1007/s00405-014-3465-9. PMID: 25547230
Nasopharyngeal Cancer: Molecular Landscape.
Bruce JP, Yip K, Bratman SV, Ito E, Liu FF
J Clin Oncol 2015 Oct 10;33(29):3346-55. Epub 2015 Sep 8 doi: 10.1200/JCO.2015.60.7846. PMID: 26351340
Unlocking the Rosetta Stone enigma for nasopharyngeal carcinoma: genetics, viral infection, and epidemiological factors.
Lung ML
Semin Cancer Biol 2012 Apr;22(2):77-8. Epub 2012 Jan 14 doi: 10.1016/j.semcancer.2012.01.006. PMID: 22266061
Nasopharyngeal carcinoma.
Brennan B
Orphanet J Rare Dis 2006 Jun 26;1:23. doi: 10.1186/1750-1172-1-23. PMID: 16800883Free PMC Article

Clinical prediction guides

Whole-Exome Sequencing Study of Familial Nasopharyngeal Carcinoma and Its Implication for Identifying High-Risk Individuals.
Wang TM, He YQ, Xue WQ, Zhang JB, Xia YF, Deng CM, Zhang WL, Xiao RW, Liao Y, Yang DW, Zhou T, Li DH, Luo LT, Tong XT, Wu YX, Chen XY, Li XZ, Zhang PF, Zheng XH, Zhang SD, Hu YZ, Wang F, Wu ZY, Zheng MQ, Huang JW, Jia YJ, Yuan LL, You R, Zhou GQ, Lu LX, Liu YY, Chen MY, Feng L, Dai W, Ren ZF, Mai HQ, Sun Y, Ma J, Zheng W, Lung ML, Jia WH
J Natl Cancer Inst 2022 Dec 8;114(12):1689-1697. doi: 10.1093/jnci/djac177. PMID: 36066420
Genetic variants in NKG2D axis and susceptibility to Epstein-Barr virus-induced nasopharyngeal carcinoma.
Viet NH, Trung NQ, Dong LT, Trung LQ, Espinoza JL
J Cancer Res Clin Oncol 2021 Mar;147(3):713-723. Epub 2021 Jan 3 doi: 10.1007/s00432-020-03475-5. PMID: 33392659
Genetic Association between NFKBIA and NFKB1 Gene Polymorphisms and the Susceptibility to Head and Neck Cancer: A Meta-Analysis.
Li L, Zhang ZT
Dis Markers 2019;2019:6523837. Epub 2019 Sep 12 doi: 10.1155/2019/6523837. PMID: 31612070Free PMC Article
Correlation between COX-2 gene polymorphism and susceptibility to nasopharyngeal carcinoma.
Sun N, Wang XQ
Eur Rev Med Pharmacol Sci 2019 Jul;23(13):5770-5778. doi: 10.26355/eurrev_201907_18315. PMID: 31298328
Epstein-Barr virus-associated malignancies.
Richtsmeier WJ, Wittels EG, Mazur EM
Crit Rev Clin Lab Sci 1987;25(2):105-36. doi: 10.3109/10408368709105879. PMID: 3038469

Recent systematic reviews

The Epstein-Barr virus latent membrane protein-1 (LMP1) 30-bp deletion and XhoI-polymorphism in nasopharyngeal carcinoma: a meta-analysis of observational studies.
da Costa VG, Marques-Silva AC, Moreli ML
Syst Rev 2015 Apr 13;4:46. doi: 10.1186/s13643-015-0037-z. PMID: 25927427Free PMC Article
Non-viral environmental risk factors for nasopharyngeal carcinoma: a systematic review.
Jia WH, Qin HD
Semin Cancer Biol 2012 Apr;22(2):117-26. Epub 2012 Jan 30 doi: 10.1016/j.semcancer.2012.01.009. PMID: 22311401

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