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Iatrogenic disease

MedGen UID:
9393
•Concept ID:
C0020732
•
Disease or Syndrome
Synonyms: Condition, Hospital-Acquired; Conditions, Hospital-Acquired; Disease, Iatrogenic; Diseases, Iatrogenic; Hospital Acquired Condition; Hospital-Acquired Condition; Hospital-Acquired Conditions; Iatrogenic Disease; Iatrogenic Diseases
SNOMED CT: Iatrogenic disorder (12456005)
 
Monarch Initiative: MONDO:0043543

Definition

A disorder which is not a natural consequence or progression of any pre-existing disorder, resulting from a diagnostic procedure or any form of therapy that is not an intended or expected outcome of its use. [from SNOMEDCT_US]

Term Hierarchy

CClinical test,  RResearch test,  OOMIM,  GGeneReviews,  VClinVar  
  • CROGVIatrogenic disease

Professional guidelines

PubMed

Diagnosis and management of duodenal perforations: a narrative review.
Ansari D, Torén W, Lindberg S, Pyrhönen HS, Andersson R
Scand J Gastroenterol 2019 Aug;54(8):939-944. Epub 2019 Jul 27 doi: 10.1080/00365521.2019.1647456. PMID: 31353983
Mechanisms underlying metabolic disturbances associated with psychosis and antipsychotic drug treatment.
Reynolds GP, McGowan OO
J Psychopharmacol 2017 Nov;31(11):1430-1436. Epub 2017 Sep 11 doi: 10.1177/0269881117722987. PMID: 28892404
Iatrogenic Opioid Withdrawal in Critically Ill Patients: A Review of Assessment Tools and Management.
Chiu AW, Contreras S, Mehta S, Korman J, Perreault MM, Williamson DR, Burry LD
Ann Pharmacother 2017 Dec;51(12):1099-1111. Epub 2017 Aug 9 doi: 10.1177/1060028017724538. PMID: 28793780

Recent clinical studies

Etiology

Avoid Iatrogenic Injuries.
Li JJ, Zhang H, Peng X, Yang SM, Bai JY, Fan CQ
Am J Gastroenterol 2023 Feb 1;118(2):202-203. Epub 2022 Sep 30 doi: 10.14309/ajg.0000000000002039. PMID: 36191272
A quality improvement programme to reduce hospital-acquired pressure injuries.
Gupta P, Shiju S, Chacko G, Thomas M, Abas A, Savarimuthu I, Omari E, Al-Balushi S, Jessymol P, Mathew S, Quinto M, McDonald I, Andrews W
BMJ Open Qual 2020 Jul;9(3) doi: 10.1136/bmjoq-2019-000905. PMID: 32727869Free PMC Article
Managing hyponatremia.
Boyle R
JAAPA 2019 Oct;32(10):48-50. doi: 10.1097/01.JAA.0000578796.15417.09. PMID: 31567743
Dysphagia in the intensive care unit: epidemiology, mechanisms, and clinical management.
Zuercher P, Moret CS, Dziewas R, Schefold JC
Crit Care 2019 Mar 28;23(1):103. doi: 10.1186/s13054-019-2400-2. PMID: 30922363Free PMC Article
Endoscope drying and its pitfalls.
Kovaleva J
J Hosp Infect 2017 Dec;97(4):319-328. Epub 2017 Jul 17 doi: 10.1016/j.jhin.2017.07.012. PMID: 28729139

Diagnosis

Iatrogenic cataracts in ROP eyes.
Vanathi M
Indian J Ophthalmol 2023 Nov;71(11):3427-3428. doi: 10.4103/IJO.IJO_2744_23. PMID: 37869997Free PMC Article
Surgery of iatrogenic bile duct injuries.
Oliverius M, Gürlich R
Rozhl Chir 2022 Fall;101(9):421-427. doi: 10.33699/PIS.2022.101.9.421-427. PMID: 36257800
Pneumonia.
Franquet E
Semin Roentgenol 2017 Jan;52(1):27-34. Epub 2016 Dec 27 doi: 10.1053/j.ro.2016.12.001. PMID: 28434501
Iatrogenic tracheobronchial rupture.
Paraschiv M
J Med Life 2014 Sep 15;7(3):343-8. Epub 2014 Sep 25 PMID: 25408752Free PMC Article
Coronary embolism.
Cheng TO
Int J Cardiol 2009 Jul 24;136(1):1-3. Epub 2009 Jan 31 doi: 10.1016/j.ijcard.2009.01.005. PMID: 19181402

Therapy

Efficacy and safety of isotonic versus hypotonic intravenous maintenance fluids in hospitalized children: an updated systematic review and meta-analysis of randomized controlled trials.
Amer BE, Abdelwahab OA, Abdelaziz A, Soliman Y, Amin AM, Mohamed MA, Albakri K, Zedan EM, Hamouda N
Pediatr Nephrol 2024 Jan;39(1):57-84. Epub 2023 Jun 26 doi: 10.1007/s00467-023-06032-7. PMID: 37365423Free PMC Article
Fatal iatrogenic cerebral β-amyloid-related arteritis in a woman treated with lecanemab for Alzheimer's disease.
Solopova E, Romero-Fernandez W, Harmsen H, Ventura-Antunes L, Wang E, Shostak A, Maldonado J, Donahue MJ, Schultz D, Coyne TM, Charidimou A, Schrag M
Nat Commun 2023 Dec 12;14(1):8220. doi: 10.1038/s41467-023-43933-5. PMID: 38086820Free PMC Article
An Iatrogenic Tattoo.
Serrano Serra JP, Ruiz Martínez J, Gil Liñán A
Actas Dermosifiliogr 2023 Oct;114(9):829. Epub 2023 Feb 4 doi: 10.1016/j.ad.2022.05.040. PMID: 36740180
Mortality and morbidity in acutely ill adults treated with liberal versus conservative oxygen therapy (IOTA): a systematic review and meta-analysis.
Chu DK, Kim LH, Young PJ, Zamiri N, Almenawer SA, Jaeschke R, Szczeklik W, Schünemann HJ, Neary JD, Alhazzani W
Lancet 2018 Apr 28;391(10131):1693-1705. Epub 2018 Apr 26 doi: 10.1016/S0140-6736(18)30479-3. PMID: 29726345
Insertion-related pain with intramedullary nailing.
Jang Y, Kempton LB, Mckinley TO, Sorkin AT
Injury 2017 Jun;48 Suppl 1:S18-S21. Epub 2017 May 5 doi: 10.1016/j.injury.2017.04.029. PMID: 28483357

Prognosis

Iatrogenic Decompensated Heart Failure.
Tran P, Banerjee P
Curr Heart Fail Rep 2020 Apr;17(2):21-27. doi: 10.1007/s11897-020-00452-4. PMID: 32086714Free PMC Article
Creutzfeldt-Jakob disease: a systematic review of global incidence, prevalence, infectivity, and incubation.
Uttley L, Carroll C, Wong R, Hilton DA, Stevenson M
Lancet Infect Dis 2020 Jan;20(1):e2-e10. doi: 10.1016/S1473-3099(19)30615-2. PMID: 31876504
Epidemiology and Clinical Correlates of AKI in Chinese Hospitalized Adults.
Xu X, Nie S, Liu Z, Chen C, Xu G, Zha Y, Qian J, Liu B, Han S, Xu A, Xu X, Hou FF
Clin J Am Soc Nephrol 2015 Sep 4;10(9):1510-8. Epub 2015 Jul 31 doi: 10.2215/CJN.02140215. PMID: 26231194Free PMC Article
Esophageal perforation.
Nirula R
Surg Clin North Am 2014 Feb;94(1):35-41. Epub 2013 Nov 5 doi: 10.1016/j.suc.2013.10.003. PMID: 24267495
Paresis acquired in the intensive care unit: a prospective multicenter study.
De Jonghe B, Sharshar T, Lefaucheur JP, Authier FJ, Durand-Zaleski I, Boussarsar M, Cerf C, Renaud E, Mesrati F, Carlet J, Raphaël JC, Outin H, Bastuji-Garin S; Groupe de Réflexion et d'Etude des Neuromyopathies en Réanimation
JAMA 2002 Dec 11;288(22):2859-67. doi: 10.1001/jama.288.22.2859. PMID: 12472328

Clinical prediction guides

Assessment and treatment of the withdrawal syndrome in paediatric intensive care units: Systematic review.
Ávila-Alzate JA, Gómez-Salgado J, Romero-Martín M, Martínez-Isasi S, Navarro-Abal Y, Fernández-García D
Medicine (Baltimore) 2020 Jan;99(5):e18502. doi: 10.1097/MD.0000000000018502. PMID: 32000360Free PMC Article
Creutzfeldt-Jakob disease: a systematic review of global incidence, prevalence, infectivity, and incubation.
Uttley L, Carroll C, Wong R, Hilton DA, Stevenson M
Lancet Infect Dis 2020 Jan;20(1):e2-e10. doi: 10.1016/S1473-3099(19)30615-2. PMID: 31876504
Dysphagia in the intensive care unit: epidemiology, mechanisms, and clinical management.
Zuercher P, Moret CS, Dziewas R, Schefold JC
Crit Care 2019 Mar 28;23(1):103. doi: 10.1186/s13054-019-2400-2. PMID: 30922363Free PMC Article
A prediction tool for hospital-acquired pressure ulcers among surgical patients: Surgical pressure ulcer risk score.
Aloweni F, Ang SY, Fook-Chong S, Agus N, Yong P, Goh MM, Tucker-Kellogg L, Soh RC
Int Wound J 2019 Feb;16(1):164-175. Epub 2018 Oct 5 doi: 10.1111/iwj.13007. PMID: 30289624Free PMC Article
Predicting Pressure Injury in Critical Care Patients: A Machine-Learning Model.
Alderden J, Pepper GA, Wilson A, Whitney JD, Richardson S, Butcher R, Jo Y, Cummins MR
Am J Crit Care 2018 Nov;27(6):461-468. doi: 10.4037/ajcc2018525. PMID: 30385537Free PMC Article

Recent systematic reviews

Natural and iatrogenic ocular manifestations of rheumatoid arthritis: a systematic review.
Dammacco R, Guerriero S, Alessio G, Dammacco F
Int Ophthalmol 2022 Feb;42(2):689-711. Epub 2021 Nov 21 doi: 10.1007/s10792-021-02058-8. PMID: 34802085Free PMC Article
Physical Therapy for Iatrogenic Facial Paralysis: A Systematic Review.
Wamkpah NS, Jeanpierre L, Lieu JEC, Del Toro D, Simon LE, Chi JJ
JAMA Otolaryngol Head Neck Surg 2020 Nov 1;146(11):1065-1072. doi: 10.1001/jamaoto.2020.3049. PMID: 32970128Free PMC Article
Creutzfeldt-Jakob disease: a systematic review of global incidence, prevalence, infectivity, and incubation.
Uttley L, Carroll C, Wong R, Hilton DA, Stevenson M
Lancet Infect Dis 2020 Jan;20(1):e2-e10. doi: 10.1016/S1473-3099(19)30615-2. PMID: 31876504
Mortality and morbidity in acutely ill adults treated with liberal versus conservative oxygen therapy (IOTA): a systematic review and meta-analysis.
Chu DK, Kim LH, Young PJ, Zamiri N, Almenawer SA, Jaeschke R, Szczeklik W, Schünemann HJ, Neary JD, Alhazzani W
Lancet 2018 Apr 28;391(10131):1693-1705. Epub 2018 Apr 26 doi: 10.1016/S0140-6736(18)30479-3. PMID: 29726345
Estimating per-act HIV transmission risk: a systematic review.
Patel P, Borkowf CB, Brooks JT, Lasry A, Lansky A, Mermin J
AIDS 2014 Jun 19;28(10):1509-19. doi: 10.1097/QAD.0000000000000298. PMID: 24809629Free PMC Article

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