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Delayed AND/OR secondary postpartum hemorrhage

MedGen UID:
96876
•Concept ID:
C0473508
•
Pathologic Function
Synonyms: Delayed Postpartum Hemorrhage; Hemorrhage, Delayed Postpartum; Postpartum Hemorrhage, Delayed
SNOMED CT: Delayed postpartum hemorrhage (23171006); Delayed AND/OR secondary postpartum hemorrhage (23171006); Hemorrhage after first 24 hours following delivery of placenta (23171006); Postpartum hemorrhage specified as delayed or secondary (23171006); Postpartum hemorrhage, delayed AND/OR secondary (23171006)

Definition

Excessive blood loss between 24 hours after delivery through four weeks that requires intervention. [from NCI]

Term Hierarchy

CClinical test,  RResearch test,  OOMIM,  GGeneReviews,  VClinVar  
  • CROGVDelayed AND/OR secondary postpartum hemorrhage

Professional guidelines

PubMed

The World Federation of ADHD International Consensus Statement: 208 Evidence-based conclusions about the disorder.
Faraone SV, Banaschewski T, Coghill D, Zheng Y, Biederman J, Bellgrove MA, Newcorn JH, Gignac M, Al Saud NM, Manor I, Rohde LA, Yang L, Cortese S, Almagor D, Stein MA, Albatti TH, Aljoudi HF, Alqahtani MMJ, Asherson P, Atwoli L, Bölte S, Buitelaar JK, Crunelle CL, Daley D, Dalsgaard S, Döpfner M, Espinet S, Fitzgerald M, Franke B, Gerlach M, Haavik J, Hartman CA, Hartung CM, Hinshaw SP, Hoekstra PJ, Hollis C, Kollins SH, Sandra Kooij JJ, Kuntsi J, Larsson H, Li T, Liu J, Merzon E, Mattingly G, Mattos P, McCarthy S, Mikami AY, Molina BSG, Nigg JT, Purper-Ouakil D, Omigbodun OO, Polanczyk GV, Pollak Y, Poulton AS, Rajkumar RP, Reding A, Reif A, Rubia K, Rucklidge J, Romanos M, Ramos-Quiroga JA, Schellekens A, Scheres A, Schoeman R, Schweitzer JB, Shah H, Solanto MV, Sonuga-Barke E, Soutullo C, Steinhausen HC, Swanson JM, Thapar A, Tripp G, van de Glind G, van den Brink W, Van der Oord S, Venter A, Vitiello B, Walitza S, Wang Y
Neurosci Biobehav Rev 2021 Sep;128:789-818. Epub 2021 Feb 4 doi: 10.1016/j.neubiorev.2021.01.022. PMID: 33549739Free PMC Article
Diagnosis, treatment and prevention of ankle sprains: update of an evidence-based clinical guideline.
Vuurberg G, Hoorntje A, Wink LM, van der Doelen BFW, van den Bekerom MP, Dekker R, van Dijk CN, Krips R, Loogman MCM, Ridderikhof ML, Smithuis FF, Stufkens SAS, Verhagen EALM, de Bie RA, Kerkhoffs GMMJ
Br J Sports Med 2018 Aug;52(15):956. Epub 2018 Mar 7 doi: 10.1136/bjsports-2017-098106. PMID: 29514819
Clinical guideline: management of gastroparesis.
Camilleri M, Parkman HP, Shafi MA, Abell TL, Gerson L; American College of Gastroenterology
Am J Gastroenterol 2013 Jan;108(1):18-37; quiz 38. Epub 2012 Nov 13 doi: 10.1038/ajg.2012.373. PMID: 23147521Free PMC Article

Recent clinical studies

Etiology

Prenatal anemia and postpartum hemorrhage risk: A systematic review and meta-analysis.
Omotayo MO, Abioye AI, Kuyebi M, Eke AC
J Obstet Gynaecol Res 2021 Aug;47(8):2565-2576. Epub 2021 May 17 doi: 10.1111/jog.14834. PMID: 34002432Free PMC Article
Postpartum Hemorrhage.
Bienstock JL, Eke AC, Hueppchen NA
N Engl J Med 2021 Apr 29;384(17):1635-1645. doi: 10.1056/NEJMra1513247. PMID: 33913640Free PMC Article
Prevention of postpartum hemorrhage.
Gonzalez-Brown V, Schneider P
Semin Fetal Neonatal Med 2020 Oct;25(5):101129. Epub 2020 Jul 15 doi: 10.1016/j.siny.2020.101129. PMID: 32782215
Postpartum hemorrhage: early identification challenges.
Andrikopoulou M, D'Alton ME
Semin Perinatol 2019 Feb;43(1):11-17. Epub 2018 Nov 14 doi: 10.1053/j.semperi.2018.11.003. PMID: 30503400
Postpartum Hemorrhage: Prevention and Treatment.
Evensen A, Anderson JM, Fontaine P
Am Fam Physician 2017 Apr 1;95(7):442-449. PMID: 28409600

Diagnosis

Latest advances in postpartum hemorrhage management.
Kumaraswami S, Butwick A
Best Pract Res Clin Anaesthesiol 2022 May;36(1):123-134. Epub 2022 Feb 24 doi: 10.1016/j.bpa.2022.02.004. PMID: 35659949
Epidemiology, prevention and management of early postpartum hemorrhage - a systematic review.
Feduniw S, Warzecha D, Szymusik I, Wielgos M
Ginekol Pol 2020;91(1):38-44. doi: 10.5603/GP.2020.0009. PMID: 32039467
Postpartum hemorrhage revisited: new challenges and solutions.
Higgins N, Patel SK, Toledo P
Curr Opin Anaesthesiol 2019 Jun;32(3):278-284. doi: 10.1097/ACO.0000000000000717. PMID: 31045634
Postpartum hemorrhage: early identification challenges.
Andrikopoulou M, D'Alton ME
Semin Perinatol 2019 Feb;43(1):11-17. Epub 2018 Nov 14 doi: 10.1053/j.semperi.2018.11.003. PMID: 30503400
Postpartum Hemorrhage: Prevention and Treatment.
Evensen A, Anderson JM, Fontaine P
Am Fam Physician 2017 Apr 1;95(7):442-449. PMID: 28409600

Therapy

Prenatal anemia and postpartum hemorrhage risk: A systematic review and meta-analysis.
Omotayo MO, Abioye AI, Kuyebi M, Eke AC
J Obstet Gynaecol Res 2021 Aug;47(8):2565-2576. Epub 2021 May 17 doi: 10.1111/jog.14834. PMID: 34002432Free PMC Article
Postpartum Hemorrhage.
Bienstock JL, Eke AC, Hueppchen NA
N Engl J Med 2021 Apr 29;384(17):1635-1645. doi: 10.1056/NEJMra1513247. PMID: 33913640Free PMC Article
Transfusion Management of Obstetric Hemorrhage.
O'Brien KL, Shainker SA, Lockhart EL
Transfus Med Rev 2018 Oct;32(4):249-255. Epub 2018 May 31 doi: 10.1016/j.tmrv.2018.05.003. PMID: 29934136
Postpartum Hemorrhage.
Newsome J, Martin JG, Bercu Z, Shah J, Shekhani H, Peters G
Tech Vasc Interv Radiol 2017 Dec;20(4):266-273. Epub 2017 Oct 10 doi: 10.1053/j.tvir.2017.10.007. PMID: 29224660
Postpartum Hemorrhage: Prevention and Treatment.
Evensen A, Anderson JM, Fontaine P
Am Fam Physician 2017 Apr 1;95(7):442-449. PMID: 28409600

Prognosis

Prenatal anemia and postpartum hemorrhage risk: A systematic review and meta-analysis.
Omotayo MO, Abioye AI, Kuyebi M, Eke AC
J Obstet Gynaecol Res 2021 Aug;47(8):2565-2576. Epub 2021 May 17 doi: 10.1111/jog.14834. PMID: 34002432Free PMC Article
Prevention of postpartum hemorrhage.
Gonzalez-Brown V, Schneider P
Semin Fetal Neonatal Med 2020 Oct;25(5):101129. Epub 2020 Jul 15 doi: 10.1016/j.siny.2020.101129. PMID: 32782215
Epidemiology, prevention and management of early postpartum hemorrhage - a systematic review.
Feduniw S, Warzecha D, Szymusik I, Wielgos M
Ginekol Pol 2020;91(1):38-44. doi: 10.5603/GP.2020.0009. PMID: 32039467
Postpartum hemorrhage revisited: new challenges and solutions.
Higgins N, Patel SK, Toledo P
Curr Opin Anaesthesiol 2019 Jun;32(3):278-284. doi: 10.1097/ACO.0000000000000717. PMID: 31045634
Postpartum hemorrhage: epidemiology, risk factors, and causes.
Oyelese Y, Ananth CV
Clin Obstet Gynecol 2010 Mar;53(1):147-56. doi: 10.1097/GRF.0b013e3181cc406d. PMID: 20142652

Clinical prediction guides

Uterine atony.
Miller HE, Ansari JR
Curr Opin Obstet Gynecol 2022 Apr 1;34(2):82-89. doi: 10.1097/GCO.0000000000000776. PMID: 35102109
Prenatal anemia and postpartum hemorrhage risk: A systematic review and meta-analysis.
Omotayo MO, Abioye AI, Kuyebi M, Eke AC
J Obstet Gynaecol Res 2021 Aug;47(8):2565-2576. Epub 2021 May 17 doi: 10.1111/jog.14834. PMID: 34002432Free PMC Article
Epidemiology, prevention and management of early postpartum hemorrhage - a systematic review.
Feduniw S, Warzecha D, Szymusik I, Wielgos M
Ginekol Pol 2020;91(1):38-44. doi: 10.5603/GP.2020.0009. PMID: 32039467
Practice Bulletin No. 183: Postpartum Hemorrhage.
Committee on Practice Bulletins-Obstetrics
Obstet Gynecol 2017 Oct;130(4):e168-e186. doi: 10.1097/AOG.0000000000002351. PMID: 28937571
Postpartum haemorrhage: prevention and treatment.
Sentilhes L, Merlot B, Madar H, Sztark F, Brun S, Deneux-Tharaux C
Expert Rev Hematol 2016 Nov;9(11):1043-1061. Epub 2016 Oct 20 doi: 10.1080/17474086.2016.1245135. PMID: 27701915

Recent systematic reviews

Prenatal anemia and postpartum hemorrhage risk: A systematic review and meta-analysis.
Omotayo MO, Abioye AI, Kuyebi M, Eke AC
J Obstet Gynaecol Res 2021 Aug;47(8):2565-2576. Epub 2021 May 17 doi: 10.1111/jog.14834. PMID: 34002432Free PMC Article
Risk Factors for Atonic Postpartum Hemorrhage: A Systematic Review and Meta-analysis.
Ende HB, Lozada MJ, Chestnut DH, Osmundson SS, Walden RL, Shotwell MS, Bauchat JR
Obstet Gynecol 2021 Feb 1;137(2):305-323. doi: 10.1097/AOG.0000000000004228. PMID: 33417319Free PMC Article
Oxytocin and postpartum depression: A systematic review.
Thul TA, Corwin EJ, Carlson NS, Brennan PA, Young LJ
Psychoneuroendocrinology 2020 Oct;120:104793. Epub 2020 Jul 6 doi: 10.1016/j.psyneuen.2020.104793. PMID: 32683141Free PMC Article
Epidemiology, prevention and management of early postpartum hemorrhage - a systematic review.
Feduniw S, Warzecha D, Szymusik I, Wielgos M
Ginekol Pol 2020;91(1):38-44. doi: 10.5603/GP.2020.0009. PMID: 32039467
Maternal and neonatal complications of fetal macrosomia: systematic review and meta-analysis.
Beta J, Khan N, Khalil A, Fiolna M, Ramadan G, Akolekar R
Ultrasound Obstet Gynecol 2019 Sep;54(3):308-318. Epub 2019 Aug 2 doi: 10.1002/uog.20279. PMID: 30938004

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