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Ovarian papillary tumor

MedGen UID:
99195
•Concept ID:
C0476121
•
Neoplastic Process
Synonyms: Ovarian Papillary Neoplasm; ovarian papillary neoplasm; Ovarian Papillary Tumor; ovarian papillary tumor; ovarian papillary tumor (morphologic abnormality); ovarian papillary tumour (morphologic abnormality); Papillary Neoplasm of Ovary; papillary neoplasm of ovary; Papillary Neoplasm of the Ovary; papillary neoplasm of the ovary; Papillary Tumor of Ovary; papillary tumor of ovary; Papillary Tumor of the Ovary; papillary tumor of the ovary; papillary tumour of ovary; papillary tumour of the ovary
 
Monarch Initiative: MONDO:0003813

Definition

A benign, borderline, or malignant epithelial tumor that arises from the ovary and is characterized by the presence of papillary proliferations. Representative examples include surface papilloma, borderline serous surface papillary tumor, and serous surface papillary adenocarcinoma. [from NCI]

Professional guidelines

PubMed

A Revised Classification System and Recommendations From the Baltimore Consensus Meeting for Neoplastic Precursor Lesions in the Pancreas.
Basturk O, Hong SM, Wood LD, Adsay NV, Albores-Saavedra J, Biankin AV, Brosens LA, Fukushima N, Goggins M, Hruban RH, Kato Y, Klimstra DS, Klöppel G, Krasinskas A, Longnecker DS, Matthaei H, Offerhaus GJ, Shimizu M, Takaori K, Terris B, Yachida S, Esposito I, Furukawa T; Baltimore Consensus Meeting
Am J Surg Pathol 2015 Dec;39(12):1730-41. doi: 10.1097/PAS.0000000000000533. PMID: 26559377Free PMC Article
International consensus guidelines for management of intraductal papillary mucinous neoplasms and mucinous cystic neoplasms of the pancreas.
Tanaka M, Chari S, Adsay V, Fernandez-del Castillo C, Falconi M, Shimizu M, Yamaguchi K, Yamao K, Matsuno S; International Association of Pancreatology
Pancreatology 2006;6(1-2):17-32. doi: 10.1159/000090023. PMID: 16327281
Treatment of micropapillary serous ovarian carcinoma (the aggressive variant of serous borderline tumors).
Seidman JD, Kurman RJ
Cancer 2002 Aug 15;95(4):675-6. doi: 10.1002/cncr.10777. PMID: 12209708

Recent clinical studies

Etiology

It Does Exist! Diagnosis and Management of Thyroid Carcinomas Originating in Struma Ovarii.
Smith LP, Brubaker LW, Wolsky RJ
Surg Pathol Clin 2023 Mar;16(1):75-86. Epub 2022 Dec 13 doi: 10.1016/j.path.2022.09.008. PMID: 36739168
What is the success of ultrasonography of benign adnexal masses?
Bayoğlu Tekin Y, Dede FS
J Obstet Gynaecol Res 2014 Feb;40(2):473-8. Epub 2013 Oct 22 doi: 10.1111/jog.12208. PMID: 24147915
Precursors to pancreatic cancer.
Hruban RH, Maitra A, Kern SE, Goggins M
Gastroenterol Clin North Am 2007 Dec;36(4):831-49, vi. doi: 10.1016/j.gtc.2007.08.012. PMID: 17996793Free PMC Article
Use of morphology to characterize and manage common adnexal masses.
Valentin L
Best Pract Res Clin Obstet Gynaecol 2004 Feb;18(1):71-89. doi: 10.1016/j.bpobgyn.2003.10.002. PMID: 15123059
Serous carcinoma in endometrial polyps.
Silva EG, Jenkins R
Mod Pathol 1990 Mar;3(2):120-8. PMID: 2326248

Diagnosis

Neoplasms in Struma Ovarii: A Review.
Tondi Resta I, Sande CM, LiVolsi VA
Endocr Pathol 2023 Dec;34(4):455-460. Epub 2023 Oct 21 doi: 10.1007/s12022-023-09789-7. PMID: 37864665
Papillary thyroid carcinoma in Struma Ovarii.
Khatchapuridze K, Kekelidze N, Tsitsishvili Z, Mchedlishvili M, Kordzaia D
Gynecol Endocrinol 2020 Aug;36(8):749-752. Epub 2020 Feb 11 doi: 10.1080/09513590.2020.1725966. PMID: 32041443
Unusual cutaneous metastatic carcinoma.
Ruiz SJ, Al Salihi S, Prieto VG, Nagarajan P, Tetzlaff MT, Curry JL, Ivan D, Torres-Cabala CA, Aung PP
Ann Diagn Pathol 2019 Dec;43:151399. Epub 2019 Aug 12 doi: 10.1016/j.anndiagpath.2019.08.003. PMID: 31675677
Thyroid-type carcinoma of struma ovarii.
Zhang X, Axiotis C
Arch Pathol Lab Med 2010 May;134(5):786-91. doi: 10.5858/134.5.786. PMID: 20441513
High-grade serous carcinoma of the ovary.
Westfall D, Roma AA, Silva EG
Ann Diagn Pathol 2009 Aug;13(4):285-90. Epub 2009 May 21 doi: 10.1016/j.anndiagpath.2009.03.005. PMID: 19608089

Therapy

Low-Dose Radiotherapy Reverses Tumor Immune Desertification and Resistance to Immunotherapy.
Herrera FG, Ronet C, Ochoa de Olza M, Barras D, Crespo I, Andreatta M, Corria-Osorio J, Spill A, Benedetti F, Genolet R, Orcurto A, Imbimbo M, Ghisoni E, Navarro Rodrigo B, Berthold DR, Sarivalasis A, Zaman K, Duran R, Dromain C, Prior J, Schaefer N, Bourhis J, Dimopoulou G, Tsourti Z, Messemaker M, Smith T, Warren SE, Foukas P, Rusakiewicz S, Pittet MJ, Zimmermann S, Sempoux C, Dafni U, Harari A, Kandalaft LE, Carmona SJ, Dangaj Laniti D, Irving M, Coukos G
Cancer Discov 2022 Jan;12(1):108-133. Epub 2021 Sep 3 doi: 10.1158/2159-8290.CD-21-0003. PMID: 34479871Free PMC Article
Sincronous malignant struma ovarii and papillary thyroid carcinoma.
Fernández Catalina P, Rego Iraeta A, Lorenzo Solar M, Sánchez Sobrino P
Endocrinol Nutr 2016 Aug-Sep;63(7):366-7. Epub 2016 Jun 11 doi: 10.1016/j.endonu.2016.05.002. PMID: 27297016
Effects of I-131 therapy on gonads and pregnancy outcome in patients with thyroid cancer.
Sioka C, Fotopoulos A
Fertil Steril 2011 Apr;95(5):1552-9. doi: 10.1016/j.fertnstert.2011.01.017. PMID: 21300333
Peritoneal papillary carcinoma.
Lele SB, Piver MS, Matharu J, Tsukada Y
Gynecol Oncol 1988 Oct;31(2):315-20. doi: 10.1016/s0090-8258(88)80010-6. PMID: 2458994
Endocrine surgery in children.
Schwartz DL, Gann DS, Haller JA Jr
Surg Clin North Am 1974 Apr;54(2):363-85. doi: 10.1016/s0039-6109(16)40285-9. PMID: 4361606

Prognosis

Unusual cutaneous metastatic carcinoma.
Ruiz SJ, Al Salihi S, Prieto VG, Nagarajan P, Tetzlaff MT, Curry JL, Ivan D, Torres-Cabala CA, Aung PP
Ann Diagn Pathol 2019 Dec;43:151399. Epub 2019 Aug 12 doi: 10.1016/j.anndiagpath.2019.08.003. PMID: 31675677
Use of synthetic stomata in abdominal carcinomatosis. Case report and literature review.
Mendoza-Sánchez F, Ángeles-Bueno WG, Montes-López GA, Mendoza-Medina DF, Díaz-Sifuentes JM, Pérez-Landeros JE
Cir Cir 2019;87(S1):28-32. doi: 10.24875/CIRU.19000605. PMID: 31501620
Imaging findings for mucinous tumors of the abdomen and pelvis.
Raposo Rodríguez L, Fernández García N, Tovar Salazar DJ, Gómez Illán R, Díaz Sánchez TB
Radiologia (Engl Ed) 2019 Sep-Oct;61(5):370-387. Epub 2019 May 9 doi: 10.1016/j.rx.2019.03.003. PMID: 31078302
Well-differentiated serous neoplasms of the ovary.
Longacre TA, Kempson RL, Hendrickson MR
Pathology (Phila) 1993;1(2):255-306. PMID: 9420921
Borderline ovarian tumors: a review of treatment.
Chambers JT
Yale J Biol Med 1989 Jul-Aug;62(4):351-65. PMID: 2556863Free PMC Article

Clinical prediction guides

Nuclear expression of NHERF1/EBP50 in Clear Cell Renal Cell Carcinoma.
Lema BE, Patricio GM, Kreimann EL
Acta Histochem 2021 Jul;123(5):151717. Epub 2021 May 6 doi: 10.1016/j.acthis.2021.151717. PMID: 33965858
Uterine cancer in Jewish Israeli BRCA1/2 mutation carriers.
Laitman Y, Michaelson-Cohen R, Levi E, Chen-Shtoyerman R, Reish O, Josefsberg Ben-Yehoshua S, Bernstein-Molho R, Keinan-Boker L, Rosengarten O, Silverman BG, Perri T, Korach J, Mor P, Ephrat Ben-Baruch N, Levy Lahad E, Friedman E; Israeli Consortium of Hereditary Breast Cancer
Cancer 2019 Mar 1;125(5):698-703. Epub 2018 Nov 29 doi: 10.1002/cncr.31842. PMID: 30489631
In vivo tumor growth of high-grade serous ovarian cancer cell lines.
Mitra AK, Davis DA, Tomar S, Roy L, Gurler H, Xie J, Lantvit DD, Cardenas H, Fang F, Liu Y, Loughran E, Yang J, Sharon Stack M, Emerson RE, Cowden Dahl KD, V Barbolina M, Nephew KP, Matei D, Burdette JE
Gynecol Oncol 2015 Aug;138(2):372-7. Epub 2015 Jun 5 doi: 10.1016/j.ygyno.2015.05.040. PMID: 26050922Free PMC Article
The histological diagnosis of metastases to the breast from extramammary malignancies.
Lee AH
J Clin Pathol 2007 Dec;60(12):1333-41. doi: 10.1136/jcp.2006.046078. PMID: 18042689Free PMC Article
Use of morphology to characterize and manage common adnexal masses.
Valentin L
Best Pract Res Clin Obstet Gynaecol 2004 Feb;18(1):71-89. doi: 10.1016/j.bpobgyn.2003.10.002. PMID: 15123059

Recent systematic reviews

Malignant struma ovarii: From case to analysis.
Ayhan S, Kilic F, Ersak B, Aytekin O, Akar S, Turkmen O, Akgul G, Toyran A, Turan T, Kimyon Comert G
J Obstet Gynaecol Res 2021 Sep;47(9):3339-3351. Epub 2021 Jul 4 doi: 10.1111/jog.14902. PMID: 34219334
Endometrial Cancer in Germline BRCA Mutation Carriers: A Systematic Review and Meta-analysis.
Matanes E, Volodarsky-Perel A, Eisenberg N, Rottenstreich M, Yasmeen A, Mitric C, Lau S, Salvador S, Gotlieb WH, Kogan L
J Minim Invasive Gynecol 2021 May;28(5):947-956. Epub 2020 Nov 27 doi: 10.1016/j.jmig.2020.11.023. PMID: 33249269
The involvement of retroperitoneal lymph nodes in primary serous-papillary peritoneal carcinoma. a systematic review of the literature.
Steinhagen PR, Sehouli J
Anticancer Res 2011 Apr;31(4):1387-94. PMID: 21508390
Pelvic mass-like florid cystic endosalpingiosis of the uterus: a case report and a review of literature.
Rosenberg P, Nappi L, Santoro A, Bufo P, Greco P
Arch Gynecol Obstet 2011 Mar;283(3):519-23. Epub 2010 Oct 8 doi: 10.1007/s00404-010-1700-1. PMID: 20931212
Serous papillary peritoneal carcinoma: unknown primary tumour, ovarian cancer counterpart or a distinct entity? A systematic review.
Pentheroudakis G, Pavlidis N
Crit Rev Oncol Hematol 2010 Jul;75(1):27-42. Epub 2009 Nov 7 doi: 10.1016/j.critrevonc.2009.10.003. PMID: 19897383

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