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Pervasive developmental disorder

MedGen UID:
99336
Concept ID:
C0524528
Mental or Behavioral Dysfunction
Synonym: Rare pervasive developmental disorder
SNOMED CT: Autism spectrum disorder (35919005); Autism (35919005); Pervasive developmental disorder (35919005)
 
Monarch Initiative: MONDO:0000594
Orphanet: ORPHA168778

Definition

A category of developmental disorders characterized by impaired communication and socialization skills. The impairments are incongruent with the individual''s developmental level or mental age. These disorders can be associated with general medical or genetic conditions. [from NCI]

Professional guidelines

PubMed

Rodrigues R, Lai MC, Beswick A, Gorman DA, Anagnostou E, Szatmari P, Anderson KK, Ameis SH
J Child Psychol Psychiatry 2021 Jun;62(6):680-700. Epub 2020 Aug 26 doi: 10.1111/jcpp.13305. PMID: 32845025
Mukherjee SB
Indian J Pediatr 2017 Apr;84(4):307-314. Epub 2017 Jan 19 doi: 10.1007/s12098-016-2272-2. PMID: 28101829
Sanchack KE, Thomas CA
Am Fam Physician 2016 Dec 15;94(12):972-979. PMID: 28075089

Recent clinical studies

Etiology

Sharma SR, Gonda X, Tarazi FI
Pharmacol Ther 2018 Oct;190:91-104. Epub 2018 May 12 doi: 10.1016/j.pharmthera.2018.05.007. PMID: 29763648
Baio J, Wiggins L, Christensen DL, Maenner MJ, Daniels J, Warren Z, Kurzius-Spencer M, Zahorodny W, Robinson Rosenberg C, White T, Durkin MS, Imm P, Nikolaou L, Yeargin-Allsopp M, Lee LC, Harrington R, Lopez M, Fitzgerald RT, Hewitt A, Pettygrove S, Constantino JN, Vehorn A, Shenouda J, Hall-Lande J, Van Naarden Braun K, Dowling NF
MMWR Surveill Summ 2018 Apr 27;67(6):1-23. doi: 10.15585/mmwr.ss6706a1. PMID: 29701730Free PMC Article
Roberts JR, Karr CJ; Council On Environmental Health
Pediatrics 2012 Dec;130(6):e1765-88. Epub 2012 Nov 26 doi: 10.1542/peds.2012-2758. PMID: 23184105Free PMC Article
McPartland J, Volkmar FR
Handb Clin Neurol 2012;106:407-18. doi: 10.1016/B978-0-444-52002-9.00023-1. PMID: 22608634Free PMC Article
Wakefield AJ, Murch SH, Anthony A, Linnell J, Casson DM, Malik M, Berelowitz M, Dhillon AP, Thomson MA, Harvey P, Valentine A, Davies SE, Walker-Smith JA
Lancet 1998 Feb 28;351(9103):637-41. doi: 10.1016/s0140-6736(97)11096-0. PMID: 9500320

Diagnosis

Joon P, Kumar A, Parle M
Pharmacol Rep 2021 Oct;73(5):1255-1264. Epub 2021 Mar 10 doi: 10.1007/s43440-021-00244-0. PMID: 33694100
Sharma SR, Gonda X, Tarazi FI
Pharmacol Ther 2018 Oct;190:91-104. Epub 2018 May 12 doi: 10.1016/j.pharmthera.2018.05.007. PMID: 29763648
Mukherjee SB
Indian J Pediatr 2017 Apr;84(4):307-314. Epub 2017 Jan 19 doi: 10.1007/s12098-016-2272-2. PMID: 28101829
Richa S, Fahed M, Khoury E, Mishara B
Arch Suicide Res 2014;18(4):327-39. doi: 10.1080/13811118.2013.824834. PMID: 24713024
McPartland J, Volkmar FR
Handb Clin Neurol 2012;106:407-18. doi: 10.1016/B978-0-444-52002-9.00023-1. PMID: 22608634Free PMC Article

Therapy

Sharma SR, Gonda X, Tarazi FI
Pharmacol Ther 2018 Oct;190:91-104. Epub 2018 May 12 doi: 10.1016/j.pharmthera.2018.05.007. PMID: 29763648
Mukherjee SB
Indian J Pediatr 2017 Apr;84(4):307-314. Epub 2017 Jan 19 doi: 10.1007/s12098-016-2272-2. PMID: 28101829
Sanchack KE, Thomas CA
Am Fam Physician 2016 Dec 15;94(12):972-979. PMID: 28075089
Roberts JR, Karr CJ; Council On Environmental Health
Pediatrics 2012 Dec;130(6):e1765-88. Epub 2012 Nov 26 doi: 10.1542/peds.2012-2758. PMID: 23184105Free PMC Article
Wakefield AJ, Murch SH, Anthony A, Linnell J, Casson DM, Malik M, Berelowitz M, Dhillon AP, Thomson MA, Harvey P, Valentine A, Davies SE, Walker-Smith JA
Lancet 1998 Feb 28;351(9103):637-41. doi: 10.1016/s0140-6736(97)11096-0. PMID: 9500320

Prognosis

Mukherjee SB
Indian J Pediatr 2017 Apr;84(4):307-314. Epub 2017 Jan 19 doi: 10.1007/s12098-016-2272-2. PMID: 28101829
Sanchack KE, Thomas CA
Am Fam Physician 2016 Dec 15;94(12):972-979. PMID: 28075089
Anitha A, Thanseem I
Adv Exp Med Biol 2015;888:71-83. doi: 10.1007/978-3-319-22671-2_5. PMID: 26663179
Quattrocki E, Friston K
Neurosci Biobehav Rev 2014 Nov;47:410-30. Epub 2014 Sep 30 doi: 10.1016/j.neubiorev.2014.09.012. PMID: 25277283Free PMC Article
Dawson G, Rogers S, Munson J, Smith M, Winter J, Greenson J, Donaldson A, Varley J
Pediatrics 2010 Jan;125(1):e17-23. Epub 2009 Nov 30 doi: 10.1542/peds.2009-0958. PMID: 19948568Free PMC Article

Clinical prediction guides

Joon P, Kumar A, Parle M
Pharmacol Rep 2021 Oct;73(5):1255-1264. Epub 2021 Mar 10 doi: 10.1007/s43440-021-00244-0. PMID: 33694100
Sharma SR, Gonda X, Tarazi FI
Pharmacol Ther 2018 Oct;190:91-104. Epub 2018 May 12 doi: 10.1016/j.pharmthera.2018.05.007. PMID: 29763648
Baio J, Wiggins L, Christensen DL, Maenner MJ, Daniels J, Warren Z, Kurzius-Spencer M, Zahorodny W, Robinson Rosenberg C, White T, Durkin MS, Imm P, Nikolaou L, Yeargin-Allsopp M, Lee LC, Harrington R, Lopez M, Fitzgerald RT, Hewitt A, Pettygrove S, Constantino JN, Vehorn A, Shenouda J, Hall-Lande J, Van Naarden Braun K, Dowling NF
MMWR Surveill Summ 2018 Apr 27;67(6):1-23. doi: 10.15585/mmwr.ss6706a1. PMID: 29701730Free PMC Article
Mukherjee SB
Indian J Pediatr 2017 Apr;84(4):307-314. Epub 2017 Jan 19 doi: 10.1007/s12098-016-2272-2. PMID: 28101829
Roberts JR, Karr CJ; Council On Environmental Health
Pediatrics 2012 Dec;130(6):e1765-88. Epub 2012 Nov 26 doi: 10.1542/peds.2012-2758. PMID: 23184105Free PMC Article

Recent systematic reviews

Rodrigues R, Lai MC, Beswick A, Gorman DA, Anagnostou E, Szatmari P, Anderson KK, Ameis SH
J Child Psychol Psychiatry 2021 Jun;62(6):680-700. Epub 2020 Aug 26 doi: 10.1111/jcpp.13305. PMID: 32845025
Cruz ACP, Ferrasa A, Muotri AR, Herai RH
Mitochondrion 2019 May;46:345-360. Epub 2018 Sep 13 doi: 10.1016/j.mito.2018.09.005. PMID: 30218715
Hirsch LE, Pringsheim T
Cochrane Database Syst Rev 2016 Jun 26;2016(6):CD009043. doi: 10.1002/14651858.CD009043.pub3. PMID: 27344135Free PMC Article
Ching H, Pringsheim T
Cochrane Database Syst Rev 2012 May 16;(5):CD009043. doi: 10.1002/14651858.CD009043.pub2. PMID: 22592735
Huband N, Ferriter M, Nathan R, Jones H
Cochrane Database Syst Rev 2010 Feb 17;2010(2):CD003499. doi: 10.1002/14651858.CD003499.pub3. PMID: 20166067Free PMC Article

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