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Increased circulating pyruvate concentration

MedGen UID:
376596
Concept ID:
C1849488
Finding
Synonym: Increased serum pyruvate
 
HPO: HP:0003542

Definition

The concentration of pyruvate in the blood circulation is above the upper limit of normal. [from HPO]

Conditions with this feature

Professional guidelines

PubMed

Schwartz RM, Boyes S, Aynsley-Green A
Dev Med Child Neurol 1989 Apr;31(2):152-60. doi: 10.1111/j.1469-8749.1989.tb03973.x. PMID: 2661288
Heaton A, Johnston DG, Haigh JW, Ward MK, Alberti KG, Kerr DN
Clin Sci (Lond) 1985 Oct;69(4):449-57. doi: 10.1042/cs0690449. PMID: 4042546

Recent clinical studies

Etiology

Baptista LC, Wilson L, Barnes S, Anton SD, Buford TW
Exp Gerontol 2024 Sep;194:112479. Epub 2024 Jun 19 doi: 10.1016/j.exger.2024.112479. PMID: 38871236
Salminen A, Määttä AM, Mäntylä P, Leskelä J, Pietiäinen M, Buhlin K, Suominen AL, Paju S, Sattler W, Sinisalo J, Pussinen PJ
J Dent Res 2024 Jan;103(1):13-21. Epub 2023 Nov 15 doi: 10.1177/00220345231203562. PMID: 37968796Free PMC Article
Guasch-Ferré M, Santos JL, Martínez-González MA, Clish CB, Razquin C, Wang D, Liang L, Li J, Dennis C, Corella D, Muñoz-Bravo C, Romaguera D, Estruch R, Santos-Lozano JM, Castañer O, Alonso-Gómez A, Serra-Majem L, Ros E, Canudas S, Asensio EM, Fitó M, Pierce K, Martínez JA, Salas-Salvadó J, Toledo E, Hu FB, Ruiz-Canela M
Am J Clin Nutr 2020 Apr 1;111(4):835-844. doi: 10.1093/ajcn/nqaa016. PMID: 32060497Free PMC Article
Consolini AE, Ragone MI, Bonazzola P, Colareda GA
Adv Exp Med Biol 2017;982:141-167. doi: 10.1007/978-3-319-55330-6_8. PMID: 28551786
Bray GA
Proc Nutr Soc 2000 Aug;59(3):373-84. doi: 10.1017/s0029665100000422. PMID: 10997653

Diagnosis

Niezen S, Connelly MA, Hirsch C, Kizer JR, Benitez ME, Minchenberg S, Perez-Matos MC, Jiang ZG, Mukamal KJ
J Am Heart Assoc 2023 Sep 5;12(17):e029960. Epub 2023 Aug 23 doi: 10.1161/JAHA.123.029960. PMID: 37609928Free PMC Article
Ferguson D, Eichler SJ, Yiew NKH, Colca JR, Cho K, Patti GJ, Shew TM, Lutkewitte AJ, Mukherjee S, McCommis KS, Niemi NM, Finck BN
Mol Metab 2023 Apr;70:101694. Epub 2023 Feb 18 doi: 10.1016/j.molmet.2023.101694. PMID: 36801448Free PMC Article
Consolini AE, Ragone MI, Bonazzola P, Colareda GA
Adv Exp Med Biol 2017;982:141-167. doi: 10.1007/978-3-319-55330-6_8. PMID: 28551786
Manco M, Calvani M, Mingrone G
Diabetes Obes Metab 2004 Nov;6(6):402-13. doi: 10.1111/j.1462-8902.2004.00356.x. PMID: 15479216
Gerich JE
Baillieres Clin Endocrinol Metab 1993 Jul;7(3):551-86. doi: 10.1016/s0950-351x(05)80207-1. PMID: 8379904

Therapy

Baptista LC, Wilson L, Barnes S, Anton SD, Buford TW
Exp Gerontol 2024 Sep;194:112479. Epub 2024 Jun 19 doi: 10.1016/j.exger.2024.112479. PMID: 38871236
Ferguson D, Eichler SJ, Yiew NKH, Colca JR, Cho K, Patti GJ, Shew TM, Lutkewitte AJ, Mukherjee S, McCommis KS, Niemi NM, Finck BN
Mol Metab 2023 Apr;70:101694. Epub 2023 Feb 18 doi: 10.1016/j.molmet.2023.101694. PMID: 36801448Free PMC Article
Guasch-Ferré M, Santos JL, Martínez-González MA, Clish CB, Razquin C, Wang D, Liang L, Li J, Dennis C, Corella D, Muñoz-Bravo C, Romaguera D, Estruch R, Santos-Lozano JM, Castañer O, Alonso-Gómez A, Serra-Majem L, Ros E, Canudas S, Asensio EM, Fitó M, Pierce K, Martínez JA, Salas-Salvadó J, Toledo E, Hu FB, Ruiz-Canela M
Am J Clin Nutr 2020 Apr 1;111(4):835-844. doi: 10.1093/ajcn/nqaa016. PMID: 32060497Free PMC Article
Consolini AE, Ragone MI, Bonazzola P, Colareda GA
Adv Exp Med Biol 2017;982:141-167. doi: 10.1007/978-3-319-55330-6_8. PMID: 28551786
Stacpoole PW, Greene YJ
Diabetes Care 1992 Jun;15(6):785-91. doi: 10.2337/diacare.15.6.785. PMID: 1600837

Prognosis

Salminen A, Määttä AM, Mäntylä P, Leskelä J, Pietiäinen M, Buhlin K, Suominen AL, Paju S, Sattler W, Sinisalo J, Pussinen PJ
J Dent Res 2024 Jan;103(1):13-21. Epub 2023 Nov 15 doi: 10.1177/00220345231203562. PMID: 37968796Free PMC Article
Niezen S, Connelly MA, Hirsch C, Kizer JR, Benitez ME, Minchenberg S, Perez-Matos MC, Jiang ZG, Mukamal KJ
J Am Heart Assoc 2023 Sep 5;12(17):e029960. Epub 2023 Aug 23 doi: 10.1161/JAHA.123.029960. PMID: 37609928Free PMC Article
Ferguson D, Eichler SJ, Yiew NKH, Colca JR, Cho K, Patti GJ, Shew TM, Lutkewitte AJ, Mukherjee S, McCommis KS, Niemi NM, Finck BN
Mol Metab 2023 Apr;70:101694. Epub 2023 Feb 18 doi: 10.1016/j.molmet.2023.101694. PMID: 36801448Free PMC Article
Ferrannini E, Baldi S, Scozzaro T, Tsimihodimos V, Tesfaye F, Shaw W, Rosenthal N, Figtree GA, Neal B, Mahaffey KW, Perkovic V, Hansen MK
Diabetes Care 2022 Aug 1;45(8):1893-1899. doi: 10.2337/dc21-2398. PMID: 35724306
Preiss D, Rankin N, Welsh P, Holman RR, Kangas AJ, Soininen P, Würtz P, Ala-Korpela M, Sattar N
Diabet Med 2016 Nov;33(11):1569-1574. Epub 2016 Mar 3 doi: 10.1111/dme.13097. PMID: 26887663

Clinical prediction guides

Baptista LC, Wilson L, Barnes S, Anton SD, Buford TW
Exp Gerontol 2024 Sep;194:112479. Epub 2024 Jun 19 doi: 10.1016/j.exger.2024.112479. PMID: 38871236
Salminen A, Määttä AM, Mäntylä P, Leskelä J, Pietiäinen M, Buhlin K, Suominen AL, Paju S, Sattler W, Sinisalo J, Pussinen PJ
J Dent Res 2024 Jan;103(1):13-21. Epub 2023 Nov 15 doi: 10.1177/00220345231203562. PMID: 37968796Free PMC Article
Ferguson D, Eichler SJ, Yiew NKH, Colca JR, Cho K, Patti GJ, Shew TM, Lutkewitte AJ, Mukherjee S, McCommis KS, Niemi NM, Finck BN
Mol Metab 2023 Apr;70:101694. Epub 2023 Feb 18 doi: 10.1016/j.molmet.2023.101694. PMID: 36801448Free PMC Article
Guasch-Ferré M, Santos JL, Martínez-González MA, Clish CB, Razquin C, Wang D, Liang L, Li J, Dennis C, Corella D, Muñoz-Bravo C, Romaguera D, Estruch R, Santos-Lozano JM, Castañer O, Alonso-Gómez A, Serra-Majem L, Ros E, Canudas S, Asensio EM, Fitó M, Pierce K, Martínez JA, Salas-Salvadó J, Toledo E, Hu FB, Ruiz-Canela M
Am J Clin Nutr 2020 Apr 1;111(4):835-844. doi: 10.1093/ajcn/nqaa016. PMID: 32060497Free PMC Article
Grynberg A, Demaison L
J Cardiovasc Pharmacol 1996;28 Suppl 1:S11-7. doi: 10.1097/00005344-199600003-00003. PMID: 8891866

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