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Lower-limb joint contracture

MedGen UID:
395285
Concept ID:
C1859523
Anatomical Abnormality; Finding
Synonyms: Contractures of the lower limbs; Contractures, lower limbs
 
HPO: HP:0005750

Definition

A limitation in the passive range of motion of a joint of the lower limb resulting from loss of elasticity in the periarticular tissues owing to structural changes of non-bony tissues, such as muscles, tendons, ligaments, joint capsules or skin. [from HPO]

Conditions with this feature

Congenital fascial dystrophy
MedGen UID:
226997
Concept ID:
C1302740
Congenital Abnormality
Progressive demyelinating neuropathy with bilateral striatal necrosis
MedGen UID:
462323
Concept ID:
C3150973
Disease or Syndrome
Thiamine metabolism dysfunction syndrome-4 (THMD4) is an autosomal recessive metabolic disorder characterized by childhood onset of episodic encephalopathy, often associated with a febrile illness, and causing transient neurologic dysfunction. Most patients recover fully, but some may have mild residual weakness. Affected individuals also develop a slowly progressive axonal polyneuropathy beginning in childhood. Brain imaging during the acute episodes shows lesions consistent with bilateral striatal degeneration or necrosis (summary by Spiegel et al., 2009). For a discussion of genetic heterogeneity of disorders due to thiamine metabolism dysfunction, see THMD1 (249270).

Professional guidelines

PubMed

Fellas A, Hawke F, Santos D, Coda A
J Paediatr Child Health 2017 Sep;53(9):836-840. Epub 2017 Aug 2 doi: 10.1111/jpc.13646. PMID: 28767173
Cartotto R, Cicuto BJ, Kiwanuka HN, Bueno EM, Pomahac B
Surg Clin North Am 2014 Aug;94(4):817-37. Epub 2014 Jun 16 doi: 10.1016/j.suc.2014.05.006. PMID: 25085090
Dragoo JL, Johnson C, McConnell J
Sports Med 2012 Jan 1;42(1):51-67. doi: 10.2165/11595680-000000000-00000. PMID: 22149697

Recent clinical studies

Etiology

Yang YY, Yuan P, Li M, Jiang L, Hong SQ
Zhongguo Dang Dai Er Ke Za Zhi 2021 Oct 15;23(10):1038-1043. doi: 10.7499/j.issn.1008-8830.2106025. PMID: 34719420Free PMC Article
Kihara K, Kawasaki Y, Yagi M, Takada S
Brain Dev 2015 Oct;37(9):853-7. Epub 2015 Mar 11 doi: 10.1016/j.braindev.2015.01.007. PMID: 25769408

Diagnosis

Yang YY, Yuan P, Li M, Jiang L, Hong SQ
Zhongguo Dang Dai Er Ke Za Zhi 2021 Oct 15;23(10):1038-1043. doi: 10.7499/j.issn.1008-8830.2106025. PMID: 34719420Free PMC Article
Kihara K, Kawasaki Y, Yagi M, Takada S
Brain Dev 2015 Oct;37(9):853-7. Epub 2015 Mar 11 doi: 10.1016/j.braindev.2015.01.007. PMID: 25769408

Clinical prediction guides

Yang YY, Yuan P, Li M, Jiang L, Hong SQ
Zhongguo Dang Dai Er Ke Za Zhi 2021 Oct 15;23(10):1038-1043. doi: 10.7499/j.issn.1008-8830.2106025. PMID: 34719420Free PMC Article

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