From HPO
Punctate palmoplantar hyperkeratosis- MedGen UID:
- 870406
- •Concept ID:
- C4024851
- •
- Disease or Syndrome
A palmoplantar keratosis characterized by keratoses with a "raindrop" pattern on the palmoplantar surface, skin lesions which may involve the whole of the palmoplantar surface, or may be more restricted in their distribution.
Cheilitis- MedGen UID:
- 3349
- •Concept ID:
- C0007971
- •
- Disease or Syndrome
Inflammation of the lip.
Oral mucosa leukoplakia- MedGen UID:
- 9738
- •Concept ID:
- C0023532
- •
- Neoplastic Process
A thickened white patch on the oral mucosa that cannot be rubbed off.
Angular cheilitis- MedGen UID:
- 526202
- •Concept ID:
- C0221237
- •
- Disease or Syndrome
A type of inflammation of the lips involving one or both of the corners of the mouth.
Acantholysis- MedGen UID:
- 1687
- •Concept ID:
- C0000887
- •
- Pathologic Function
The loss of intercellular connections, such as desmosomes, resulting in loss of cohesion between keratinocytes.
Pruritus- MedGen UID:
- 19534
- •Concept ID:
- C0033774
- •
- Sign or Symptom
Pruritus is an itch or a sensation that makes a person want to scratch. This term refers to an abnormally increased disposition to experience pruritus.
Onycholysis- MedGen UID:
- 39324
- •Concept ID:
- C0085661
- •
- Disease or Syndrome
Detachment of the nail from the nail bed.
Dry skin- MedGen UID:
- 56250
- •Concept ID:
- C0151908
- •
- Sign or Symptom
Skin characterized by the lack of natural or normal moisture.
Epidermal acanthosis- MedGen UID:
- 65136
- •Concept ID:
- C0221270
- •
- Finding
Diffuse hypertrophy or thickening of the stratum spinosum of the epidermis (prickle cell layer of the skin).
Scaling skin- MedGen UID:
- 472970
- •Concept ID:
- C0237849
- •
- Finding
Refers to the loss of the outer layer of the epidermis in large, scale-like flakes.
Leukonychia- MedGen UID:
- 68698
- •Concept ID:
- C0240182
- •
- Finding
White discoloration of the nails.
Fragile skin- MedGen UID:
- 66826
- •Concept ID:
- C0241181
- •
- Finding
Skin that splits easily with minimal injury.
Knuckle pads- MedGen UID:
- 78103
- •Concept ID:
- C0264000
- •
- Disease or Syndrome
Skoog (1948) defined knuckle pads as 'subcutaneous nodules on the dorsal aspect of the proximal interphalangeal joints.'
Phrynoderma- MedGen UID:
- 83101
- •Concept ID:
- C0334013
- •
- Disease or Syndrome
A skin condition characterized by excessive development of keratin in hair follicles, resulting in rough, cone-shaped, elevated papules resulting from closure of hair follicles with a white plug of sebum.
Hyperkeratosis- MedGen UID:
- 209030
- •Concept ID:
- C0870082
- •
- Disease or Syndrome
Hyperkeratosis is thickening of the outer layer of the skin, the stratum corneum, which is composed of large, polyhedral, plate-like envelopes filled with keratin which are the dead cells that have migrated up from the stratum granulosum.
Abnormal blistering of the skin- MedGen UID:
- 412159
- •Concept ID:
- C2132198
- •
- Finding
The presence of one or more bullae on the skin, defined as fluid-filled blisters more than 5 mm in diameter with thin walls.
Telangiectases of the cheeks- MedGen UID:
- 767501
- •Concept ID:
- C3554587
- •
- Finding
Telangiectases (small dilated blood vessels) located near the surface of the skin of the cheeks.
- Abnormality of head or neck
- Abnormality of limbs
- Abnormality of the integument