From HPO
Burkitt lymphoma- MedGen UID:
- 2377
- •Concept ID:
- C0006413
- •
- Neoplastic Process
Burkitt lymphoma is a rare, aggressive B-cell lymphoma that accounts for 30 to 50% of lymphomas in children but only 1 to 2% of lymphomas in adults (Harris and Horning, 2006). It results from chromosomal translocations that involve the MYC gene (190080) and either the lambda or the kappa light chain immunoglobulin genes (147220, 147200). Burkitt lymphoma is causally related to the Epstein-Barr virus (EBV), although the pathogenetic mechanisms are not clear.
Disseminated cutaneous warts- MedGen UID:
- 1708110
- •Concept ID:
- C5139200
- •
- Neoplastic Process
Multiple skin warts located in multiple parts of the body, e.g., neck, trunks, and extremities.
Emphysema- MedGen UID:
- 18764
- •Concept ID:
- C0034067
- •
- Disease or Syndrome
A subcategory of chronic obstructive pulmonary disease (COPD). It occurs in people who smoke and suffer from chronic bronchitis. It is characterized by inflation of the alveoli, alveolar wall damage, and reduction in the number of alveoli, resulting in difficulty breathing.
Stomatitis- MedGen UID:
- 52511
- •Concept ID:
- C0038362
- •
- Disease or Syndrome
Stomatitis is an inflammation of the mucous membranes of any of the structures in the mouth.
Increased proportion of exhausted T cells- MedGen UID:
- 1620482
- •Concept ID:
- C4531071
- •
- Finding
An abnormally elevated proportion of exhausted T cells (Tex) among circulating T cells. T cell exhaustion is a distinct differentiation state that can be distinguished from naive, effector, and memory T cells. Compared to effector (TE) and memory (TMEM) T cells, exhausted T cells (TEX) display impaired effector functions (e.g., rapid production of effector cytokines, cytotoxicity). TEX have limited proliferative potential, especially compared to some subsets of TMEM and naive T cells.
Facial erythema- MedGen UID:
- 65986
- •Concept ID:
- C0239488
- •
- Finding
Redness of the skin of the face, caused by hyperemia of the capillaries in the lower layers of the skin.
- Abnormality of the immune system
- Abnormality of the integument
- Abnormality of the respiratory system
- Neoplasm