MedGen

This term applies to a family member in whom the diagnosis that is the primary focus of investigation is excluded. [from HPO]

Asthma-related traits include clinical symptoms of asthma, such as coughing, wheezing, and dyspnea; bronchial hyperresponsiveness (BHR) as assessed by methacholine challenge test; serum IgE levels; atopy; and atopic dermatitis (Laitinen et al., 2001; Illig and Wjst, 2002; Pillai et al., 2006). For a general phenotypic description and a discussion of genetic heterogeneity of asthma, see 600807. [from OMIM]

Bacterial toxic shock syndrome (TSS) is a potentially fatal, acute disease characterized by a sudden onset of high fever along with nausea, myalgia, vomiting and multisystem organ involvement, potentially leading to shock and death. TSS is mediated by superantigenic toxins, usually caused by an infection with <i>Staphylococcus aureus</i> in staphylococcal TSS (see this term) or <i>Streptococcus pyogenes</i> in streptococcal TSS (see this term). [from ORDO]