Pyrin Domain

A protein interaction domain of the death domain superfamily. It is characterized by a 6-helix bundle similar to those that occur in DEATH DOMAIN RECEPTORS. Pyrin domains are present in a variety of proteins, especially those that function in INFLAMMASOMES; AUTOPHAGY; and APOPTOSIS. They form homodimers or heterodimers with death domain proteins to facilitate the assembly of signaling complexes.

Year introduced: 2017

PubMed search builder options

Subheadings:

Restrict to MeSH Major Topic.

Do not include MeSH terms found below this term in the MeSH hierarchy.

Tree Number(s): G02.111.570.820.709.275.750.500.395.875

MeSH Unique ID: D000071196

Entry Terms:

• Pyrin Domains
• PYD Domain
• PYD Domains
• PADD Domain
• PADD Domains
• PAAD-DAPIN-PYRIN Domain
• PAAD DAPIN PYRIN Domain
• PAAD-DAPIN-PYRIN Domains
• DAPIN Domain
• DAPIN Domains

Previous Indexing:

• Cytoskeletal Proteins (2001-2016)
• Protein Structure, Tertiary (2001-2016)

See Also:

• Pyrin

All MeSH Categories
Phenomena and Processes Category
Chemical Phenomena
Biochemical Phenomena
Molecular Structure
Molecular Conformation
Protein Conformation
Protein Structural Elements
Protein Domains
Protein Interaction Domains and Motifs
Death Domain Superfamily
Pyrin Domain