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mTOR Associated Protein, LST8 Homolog

An adaptor protein, consisting of seven WD REPEATS along its length, that functions as a component of the MECHANISTIC TARGET OF RAPAMYCIN COMPLEX 1 and mTORC2 COMPLEX. It interacts directly with mTOR to enhance its kinase activity and stabilizes the mTOR-RPTOR PROTEIN interaction in nutrient-poor conditions, favoring RPTOR inhibition of mTOR activity.

Year introduced: 2018

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Subheadings:

Tree Number(s): D05.500.337.250, D08.811.913.696.620.682.700.931.500.250, D12.644.360.024.310, D12.776.157.057.073, D12.776.476.024.389, D12.776.476.563.931.500.250

MeSH Unique ID: D000076242

Entry Terms:

  • GBetaL Protein
  • mLST8 Protein
  • G protein beta Subunit-like Polypeptide
  • G protein beta Subunit like Polypeptide

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