Genes, Immunoglobulin

Genes encoding the different subunits of the IMMUNOGLOBULINS, for example the IMMUNOGLOBULIN LIGHT CHAIN GENES and the IMMUNOGLOBULIN HEAVY CHAIN GENES. The heavy and light immunoglobulin genes are present as gene segments in the germline cells. The completed genes are created when the segments are shuffled and assembled (B-LYMPHOCYTE GENE REARRANGEMENT) during B-LYMPHOCYTE maturation. The gene segments of the human light and heavy chain germline genes are symbolized V (variable), J (joining) and C (constant). The heavy chain germline genes have an additional segment D (diversity).

Year introduced: 1988

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Tree Number(s): G05.360.340.024.340.335, G12.500.299

MeSH Unique ID: D005803

Entry Terms:

• Genes, Ig
• Gene, Ig
• Ig Gene
• Ig Genes
• Immunoglobulin Genes
• Gene, Immunoglobulin
• Immunoglobulin Gene

Previous Indexing:

• Genes, Structural (1972-1987)
• Immunoglobulins (1972-1987)
• specific immunoglobulin chain or region (1975-1987)

See Also:

• Immunogenetics
• Immunoglobulin Allotypes
• Immunoglobulins
• Immunoglobulin Subunits

All MeSH Categories
Phenomena and Processes Category
Genetic Phenomena
Genetic Structures
Genome
Genome Components
Genes
Genes, Immunoglobulin
Genes, Immunoglobulin Heavy Chain
Hinge Exons
Immunoglobulin Switch Region
Genes, Immunoglobulin Light Chain
VDJ Exons

All MeSH Categories
Phenomena and Processes Category
Immune System Phenomena
Immunogenetic Phenomena
Genes, Immunoglobulin