Immunoglobulin Switch Region

A site located in the INTRONS at the 5' end of each constant region segment of a immunoglobulin heavy-chain gene where recombination (or rearrangement) occur during IMMUNOGLOBULIN CLASS SWITCHING. Ig switch regions are found on genes encoding all five classes (IMMUNOGLOBULIN ISOTYPES) of IMMUNOGLOBULIN HEAVY CHAINS.

Year introduced: 1988

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Do not include MeSH terms found below this term in the MeSH hierarchy.

Tree Number(s): G05.360.340.024.340.137.430, G05.360.340.024.340.335.300.500

MeSH Unique ID: D007134

Entry Terms:

• Immunoglobulin Switch Regions
• Region, Immunoglobulin Switch
• Regions, Immunoglobulin Switch
• Switch Regions, Immunoglobulin
• Ig Switch Region
• Ig Switch Regions
• Region, Ig Switch
• Regions, Ig Switch
• Switch Region, Ig
• Switch Regions, Ig
• Ig Switch Sequences
• Ig Switch Sequence
• Sequence, Ig Switch
• Sequences, Ig Switch
• Switch Sequence, Ig
• Switch Sequences, Ig
• Switch Region, Immunoglobulin
• Heavy-Chain Mu Switch Region

Previous Indexing:

• Genes, Structural (1977-1987)
• Immunoglobulin Constant Region (1979-1987)
• Immunoglobulin Variable Region (1977-1987)

See Also:

• Immunoglobulin Class Switching

All MeSH Categories
Phenomena and Processes Category
Genetic Phenomena
Genetic Structures
Genome
Genome Components
Genes
Gene Components
Immunoglobulin Switch Region

All MeSH Categories
Phenomena and Processes Category
Genetic Phenomena
Genetic Structures
Genome
Genome Components
Genes
Genes, Immunoglobulin
Genes, Immunoglobulin Heavy Chain
Immunoglobulin Switch Region