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Nucleic Acid Heteroduplexes

Double-stranded nucleic acid molecules (DNA-DNA or DNA-RNA) which contain regions of nucleotide mismatches (non-complementary). In vivo, these heteroduplexes can result from mutation or genetic recombination; in vitro, they are formed by nucleic acid hybridization. Electron microscopic analysis of the resulting heteroduplexes facilitates the mapping of regions of base sequence homology of nucleic acids.

Year introduced: 1980

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Tree Number(s): D13.444.500

MeSH Unique ID: D009692

Entry Terms:

  • Heteroduplexes, Nucleic Acid
  • Acid Heteroduplexes, Nucleic
  • Heteroduplex DNA
  • DNA, Heteroduplex

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