Spleen Focus-Forming Viruses

Strains of MURINE LEUKEMIA VIRUS that are replication-defective and rapidly transforming. The envelope gene plays an essential role in initiating erythroleukemia (LEUKEMIA, ERYTHROBLASTIC, ACUTE), manifested by splenic foci, SPLENOMEGALY, and POLYCYTHEMIA. Spleen focus-forming viruses are generated by recombination with endogenous retroviral sequences.

Year introduced: 1991(1986)

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Tree Number(s): B04.613.807.375.525.850, B04.820.650.375.525.850

MeSH Unique ID: D013155

Registry Number: txid11819

Entry Terms:

• Focus-Forming Viruses, Spleen
• Focus-Forming Virus, Spleen
• Spleen Focus-Forming Virus
• Spleen Focus Forming Viruses
• SFFV
• Friend spleen focus-forming virus
• Friend spleen focus forming virus
• Rauscher Spleen Focus-Forming Virus

Previous Indexing:

• Friend Virus (1966-1985)
• Leukemia, Experimental (1966-1985)
• Mouse Leukemia Viruses (1966-1985)

All MeSH Categories
Organisms Category
Viruses
Oncogenic Viruses
Retroviridae
Gammaretrovirus
Leukemia Virus, Murine
Spleen Focus-Forming Viruses

All MeSH Categories
Organisms Category
Viruses
RNA Viruses
Retroviridae
Gammaretrovirus
Leukemia Virus, Murine
Spleen Focus-Forming Viruses