Cytochrome P-450 CYP2B1
A major cytochrome P-450 enzyme which is inducible by PHENOBARBITAL in both the LIVER and SMALL INTESTINE. It is active in the metabolism of compounds like pentoxyresorufin, TESTOSTERONE, and ANDROSTENEDIONE. This enzyme, encoded by CYP2B1 gene, also mediates the activation of CYCLOPHOSPHAMIDE and IFOSFAMIDE to MUTAGENS.
Year introduced: 1997
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Subheadings:
Tree Number(s): D08.244.453.005.550, D08.244.453.491.313, D08.811.682.690.708.170.010.550, D08.811.682.690.708.170.450.313, D12.776.422.220.453.010.550, D12.776.422.220.453.491.313
MeSH Unique ID: D019362
Registry Number: EC 1.14.14.1
Entry Terms:
- Cytochrome P 450 CYP2B1
- 7-Benzyloxyresorufin O-Dealkylase
- 7 Benzyloxyresorufin O Dealkylase
- PROD
- CYP 2B1
- Cytochrome P450 2B1
- 7-Pentylresorufin O-Depentylase
- 7 Pentylresorufin O Depentylase
- Benzyloxyresorufin O-Dealkylase
- Benzyloxyresorufin O Dealkylase
- CYP2B1
- Pentoxyresorufin O-Dealkylase
- O-Dealkylase, Pentoxyresorufin
- Pentoxyresorufin O Dealkylase
- BROD
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