Ribosomal Protein S6 Kinases, 70-kDa

A family of ribosomal protein S6 kinases that are considered the major physiological kinases for RIBOSOMAL PROTEIN S6. Unlike RIBOSOMAL PROTEIN S6 KINASES, 90KDa the proteins in this family are sensitive to the inhibitory effects of RAPAMYCIN and contain a single kinase domain. They are referred to as 70kDa proteins, however ALTERNATIVE SPLICING of mRNAs for proteins in this class also results in 85kDa variants being formed.

Year introduced: 2005(2003)

PubMed search builder options

Subheadings:

Restrict to MeSH Major Topic.

Do not include MeSH terms found below this term in the MeSH hierarchy.

Tree Number(s): D08.811.913.696.620.682.700.862.249, D12.776.476.563.862.249

MeSH Unique ID: D038762

Registry Number: EC 2.7.11.1

Entry Terms:

• Ribosomal Protein S6 Kinases, 70 kDa
• p70 S6 Kinase
• S6 Kinase, p70
• p70s6k

Previous Indexing:

• Ribosomal Protein S6 Kinases (1990-2002)

All MeSH Categories
Chemicals and Drugs Category
Enzymes and Coenzymes
Enzymes
Transferases
Phosphotransferases
Phosphotransferases (Alcohol Group Acceptor)
Protein Kinases
Protein Serine-Threonine Kinases
Ribosomal Protein S6 Kinases
Ribosomal Protein S6 Kinases, 70-kDa

All MeSH Categories
Chemicals and Drugs Category
Amino Acids, Peptides, and Proteins
Proteins
Intracellular Signaling Peptides and Proteins
Protein Serine-Threonine Kinases
Ribosomal Protein S6 Kinases
Ribosomal Protein S6 Kinases, 70-kDa