Suppressor of Cytokine Signaling Proteins

A family of structurally related proteins that are induced by CYTOKINES and negatively regulate cytokine-mediated SIGNAL TRANSDUCTION PATHWAYS. SOCS proteins contain a central SH2 DOMAIN and a C-terminal region of homology known as the SOCS box.

Year introduced: 2006

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Tree Number(s): D12.644.360.024.374, D12.776.157.057.249, D12.776.476.024.437

MeSH Unique ID: D050826

Entry Terms:

• SOCS Proteins
• Suppressors of Cytokine Signaling Proteins

All MeSH Categories
Chemicals and Drugs Category
Amino Acids, Peptides, and Proteins
Peptides
Intracellular Signaling Peptides and Proteins
Adaptor Proteins, Signal Transducing
Suppressor of Cytokine Signaling Proteins
Suppressor of Cytokine Signaling 1 Protein
Suppressor of Cytokine Signaling 3 Protein

All MeSH Categories
Chemicals and Drugs Category
Amino Acids, Peptides, and Proteins
Proteins
Carrier Proteins
Adaptor Proteins, Signal Transducing
Suppressor of Cytokine Signaling Proteins
Suppressor of Cytokine Signaling 1 Protein
Suppressor of Cytokine Signaling 3 Protein

All MeSH Categories
Chemicals and Drugs Category
Amino Acids, Peptides, and Proteins
Proteins
Intracellular Signaling Peptides and Proteins
Adaptor Proteins, Signal Transducing
Suppressor of Cytokine Signaling Proteins
Suppressor of Cytokine Signaling 1 Protein
Suppressor of Cytokine Signaling 3 Protein