Interferon Regulatory Factors
A family of transcription factors that share an N-terminal HELIX-TURN-HELIX MOTIF and bind INTERFERON-inducible promoters to control GENE expression. IRF proteins bind specific DNA sequences such as interferon-stimulated response elements, interferon regulatory elements, and the interferon consensus sequence.
Year introduced: 2006
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Subheadings:
Tree Number(s): D12.644.360.024.302, D12.776.157.057.050, D12.776.260.504, D12.776.476.024.385, D12.776.930.332
MeSH Unique ID: D050835
Entry Terms:
- Interferon Regulatory Factor
- Factor, Interferon Regulatory
- Regulatory Factor, Interferon
- IRF Transcription Factors
- Transcription Factors, IRF