Interferon Regulatory Factor-3

An interferon regulatory factor that is expressed constitutively and undergoes POST-TRANSLATIONAL MODIFICATION following viral infection. PHOSPHORYLATION of IRF-3 causes the protein to be translocated from the CYTOPLASM to CELL NUCLEUS where it binds DNA, and activates transcription.

Year introduced: 2006(1996)

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Tree Number(s): D12.644.360.024.302.374, D12.776.157.057.050.374, D12.776.260.504.374, D12.776.476.024.385.374, D12.776.744.562, D12.776.930.332.374

MeSH Unique ID: D050838

Entry Terms:

• Interferon Regulatory Factor 3
• IRF-3 Transcription Factor
• IRF 3 Transcription Factor
• Transcription Factor, IRF-3
• IFN-Regulatory Factor 3
• IFN Regulatory Factor 3

All MeSH Categories
Chemicals and Drugs Category
Amino Acids, Peptides, and Proteins
Peptides
Intracellular Signaling Peptides and Proteins
Adaptor Proteins, Signal Transducing
Interferon Regulatory Factors
Interferon Regulatory Factor-3

All MeSH Categories
Chemicals and Drugs Category
Amino Acids, Peptides, and Proteins
Proteins
Carrier Proteins
Adaptor Proteins, Signal Transducing
Interferon Regulatory Factors
Interferon Regulatory Factor-3

All MeSH Categories
Chemicals and Drugs Category
Amino Acids, Peptides, and Proteins
Proteins
DNA-Binding Proteins
Interferon Regulatory Factors
Interferon Regulatory Factor-3

All MeSH Categories
Chemicals and Drugs Category
Amino Acids, Peptides, and Proteins
Proteins
Intracellular Signaling Peptides and Proteins
Adaptor Proteins, Signal Transducing
Interferon Regulatory Factors
Interferon Regulatory Factor-3

All MeSH Categories
Chemicals and Drugs Category
Amino Acids, Peptides, and Proteins
Proteins
Phosphoproteins
Interferon Regulatory Factor-3

All MeSH Categories
Chemicals and Drugs Category
Amino Acids, Peptides, and Proteins
Proteins
Transcription Factors
Interferon Regulatory Factors
Interferon Regulatory Factor-3