X-Linked Inhibitor of Apoptosis Protein

An inhibitor of apoptosis protein that is translated by a rare cap-independent mechanism. It blocks caspase-mediated cellular destruction by inhibiting CASPASE 3; CASPASE 7; and CASPASE 9.

Year introduced: 2006(1996)

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Tree Number(s): D08.811.464.938.750.210.750, D12.644.360.075.437.750, D12.776.476.075.437.750

MeSH Unique ID: D051636

Entry Terms:

• X Linked Inhibitor of Apoptosis Protein
• XIAP Protein
• X-Linked IAP Protein
• IAP Protein, X-Linked
• X Linked IAP Protein

Pharmacologic Action:

• Caspase Inhibitors

All MeSH Categories
Chemicals and Drugs Category
Enzymes and Coenzymes
Enzymes
Ligases
Ubiquitin-Protein Ligase Complexes
Ubiquitin-Protein Ligases
Inhibitor of Apoptosis Proteins
X-Linked Inhibitor of Apoptosis Protein

All MeSH Categories
Chemicals and Drugs Category
Amino Acids, Peptides, and Proteins
Peptides
Intracellular Signaling Peptides and Proteins
Apoptosis Regulatory Proteins
Inhibitor of Apoptosis Proteins
X-Linked Inhibitor of Apoptosis Protein

All MeSH Categories
Chemicals and Drugs Category
Amino Acids, Peptides, and Proteins
Proteins
Intracellular Signaling Peptides and Proteins
Apoptosis Regulatory Proteins
Inhibitor of Apoptosis Proteins
X-Linked Inhibitor of Apoptosis Protein