Fanconi Anemia Complementation Group L Protein
An E3 UBIQUITIN LIGASE that plays a key role in the DNA damage response pathway of FANCONI ANEMIA PROTEINS. It is associated with mono-ubiquitination of FANCD2 PROTEIN and the redistribution of FANCD2 to nuclear foci containing BRCA1 PROTEIN.
Year introduced: 2006 (2003)
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Subheadings:
Tree Number(s): D08.811.464.938.750.186, D12.776.313.937
MeSH Unique ID: D052240
Registry Number: EC 2.3.2.27
Entry Terms:
- Fanconi Anemia Group L Protein
- Fanconi Anemia Group L Complementing Protein
- FANCL Protein
- PHD Finger Protein 9
- Ubiquitin Ligase Protein PHF9