Caspase 10
A long pro-domain caspase that contains a death effector domain in its pro-domain region. Activation of this enzyme can occur via the interaction of its N-terminal death effector domain with DEATH DOMAIN RECEPTOR SIGNALING ADAPTOR PROTEINS. Caspase 10 plays a role in APOPTOSIS by cleaving and activating EFFECTOR CASPASES. Several isoforms of this protein exist due to multiple alternative splicing of its MESSENGER RNA.
Year introduced: 2007(1998)
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Subheadings:
Tree Number(s): D08.811.277.656.262.500.126.550.910, D08.811.277.656.300.200.126.550.910, D12.776.476.075.405.550.910
MeSH Unique ID: D053455
Registry Number: EC 3.4.22.-
Entry Terms:
- Caspase-10
- Caspase 10a
- Caspase 10-a
- Caspase 10 a
- Mch4 Protease
- Protease, Mch4
- Caspase 10c
- Caspase 10-c
- Caspase 10 c
- Caspase 10d
- Caspase 10-d
- Caspase 10 d
See Also: