RecName: Full=UDP-N-acetylhexosamine pyrophosphorylase; AltName: Full= - Protein

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A missense mutation in a patient with developmental delay affects the activity and structure of the hexosamine biosynthetic pathway enzyme AGX1. [FEBS Lett. 2021]
A missense mutation in a patient with developmental delay affects the activity and structure of the hexosamine biosynthetic pathway enzyme AGX1.
Chen X, Raimi OG, Ferenbach AT, van Aalten DMF. FEBS Lett. 2021 Jan; 595(1):110-122. Epub 2020 Nov 18.
Quantitative Proteomics of Urinary Bladder Cancer Cell Lines Identify UAP1 as a Potential Therapeutic Target. [Genes (Basel). 2020]
Quantitative Proteomics of Urinary Bladder Cancer Cell Lines Identify UAP1 as a Potential Therapeutic Target.
Puttamallesh VN, Deb B, Gondkar K, Jain A, Nair B, Pandey A, Chatterjee A, Gowda H, Kumar P. Genes (Basel). 2020 Jul 8; 11(7). Epub 2020 Jul 8.
UAP1 is overexpressed in prostate cancer and is protective against inhibitors of N-linked glycosylation. [Oncogene. 2015]
UAP1 is overexpressed in prostate cancer and is protective against inhibitors of N-linked glycosylation.
Itkonen HM, Engedal N, Babaie E, Luhr M, Guldvik IJ, Minner S, Hohloch J, Tsourlakis MC, Schlomm T, Mills IG. Oncogene. 2015 Jul; 34(28):3744-50. Epub 2014 Sep 22.

RefSeq protein isoforms
See 20 reference sequence protein isoforms for the UAP1 gene.

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Q16222 [Domain Mapping of Disease Mut...]
Q16222
Domain Mapping of Disease Mutations
Transcript/Protein Information [PANTHER Classification System]
Transcript/Protein Information
PANTHER Classification System
Reactome [Reactome]
Reactome
reagents [ExactAntigen/Labome]
reagents
ExactAntigen/Labome
reagent reviews [ExactAntigen/Labome]
reagent reviews
ExactAntigen/Labome
Evolutionary Trace of Functional Site [Evolutionary Trace of Functio...]
Evolutionary Trace of Functional Site

RecName: Full=UDP-N-acetylhexosamine pyrophosphorylase; AltName: Full=Antigen X;...
RecName: Full=UDP-N-acetylhexosamine pyrophosphorylase; AltName: Full=Antigen X; Short=AGX; AltName: Full=Protein-pyrophosphorylation enzyme; AltName: Full=Sperm-associated antigen 2; AltName: Full=UDP-N-acetylgalactosamine pyrophosphorylase; AltName: Full=UDP-N-acetylglucosamine pyrophosphorylase
gi|68846235|sp|Q16222.3|UAP1_HUMAN

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