RecName: Full=Ceramide kinase; Short=hCERK; AltName: Full=Acylsphingos - Protein

Run BLAST
Find regions of similarity between this sequence and other sequences using BLAST.
Identify Conserved Domains
View conserved domains detected in this protein sequence using CD-search.
Highlight Sequence Features
Opens the Highlight Feature Bar and highlights feature annotations from the FEATURES table of the record. The Highlight Feature Bar can be used to navigate to and highlight other features and provides links to display the highlighted region separately. Links in the FEATURES table will also highlight the corresponding region of the sequence. More...
Find in this Sequence
Finds sub-sequences or patterns in the sequence and highlights the matching regions. The tool works with standard single letter nucleotide or protein codes including ambiguities and can match Prosite patterns in protein sequences. More...

Ceramide kinase confers tamoxifen resistance in estrogen receptor-positive breast cancer by altering sphingolipid metabolism. [Pharmacol Res. 2023]
Ceramide kinase confers tamoxifen resistance in estrogen receptor-positive breast cancer by altering sphingolipid metabolism.
Huang C, Su L, Chen Y, Wu S, Sun R, Xu Q, Qiu X, Yang C, Kong X, Qin H, et al. Pharmacol Res. 2023 Jan; 187:106558. Epub 2022 Nov 21.
Ceramide kinase regulates TNF-α-induced immune responses in human monocytic cells. [Sci Rep. 2021]
Ceramide kinase regulates TNF-α-induced immune responses in human monocytic cells.
Al-Rashed F, Ahmad Z, Snider AJ, Thomas R, Kochumon S, Melhem M, Sindhu S, Obeid LM, Al-Mulla F, Hannun YA, et al. Sci Rep. 2021 Apr 15; 11(1):8259. Epub 2021 Apr 15.
Ceramide Kinase Is Upregulated in Metastatic Breast Cancer Cells and Contributes to Migration and Invasion by Activation of PI 3-Kinase and Akt. [Int J Mol Sci. 2020]
Ceramide Kinase Is Upregulated in Metastatic Breast Cancer Cells and Contributes to Migration and Invasion by Activation of PI 3-Kinase and Akt.
Schwalm S, Erhardt M, Römer I, Pfeilschifter J, Zangemeister-Wittke U, Huwiler A. Int J Mol Sci. 2020 Feb 19; 21(4). Epub 2020 Feb 19.

PubMed
PubMed articles cited by protein sequence record
Taxonomy
Taxonomy sequences associated with protein record
BioSystems
BioSystems
CDD Search Results
Display conserved domains within a protein
Conserved Domains (Concise)
Link to a concise list of conserved domains in a protein
Conserved Domains (Full)
Link to conserved domains within a protein
Domain Relatives
Display proteins with similar conserved domain architecture
Full text in PMC
Free full text articles in PMC
Gene
Link to related Genes
OMIM
OMIM records associated with protein sequence
Protein (RefSeq)
Protein gi (UniProtKB) to protein gi (refseq)
PubMed (Weighted)
Links to pubmed

Transcript/Protein Information [PANTHER Classification System]
Transcript/Protein Information
PANTHER Classification System
Reactome [Reactome]
Reactome
reagents [ExactAntigen/Labome]
reagents
ExactAntigen/Labome

RecName: Full=Ceramide kinase; Short=hCERK; AltName: Full=Acylsphingosine kinase...
RecName: Full=Ceramide kinase; Short=hCERK; AltName: Full=Acylsphingosine kinase; AltName: Full=Lipid kinase 4; Short=LK4
gi|30172885|sp|Q8TCT0.1|CERK1_HUMAN

Protein
601509802F1 NIH_MGC_71 Homo sapiens cDNA clone IMAGE:3911352 5', mRNA sequence
601509802F1 NIH_MGC_71 Homo sapiens cDNA clone IMAGE:3911352 5', mRNA sequence
gi|10340123|gnl|dbEST|6169813|gb|BE 5.1|

Nucleotide

Your browsing activity is empty.

Activity recording is turned off.

Protein